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Virtual clinical trials could transform the development of new drugs

New cutting-edge research undertaken at the University of Leicester could revolutionize the way new drugs are developed and the way patients are cared for, through a pioneering new approach using virtual clinical trials.

8 Mar 2021

SARS-CoV-2 can make itself unrecognizable to immune response by T-killer cells through mutations

The body's immune response plays a crucial role in the course of a SARS-CoV-2 infection. In addition to antibodies, the so-called T-killer cells, are also responsible for detecting viruses in the body and eliminating them.

5 Mar 2021

Study reveals process behind key cellular change in amyotrophic lateral sclerosis

A research team has discovered the trigger of a crucial cellular change in amyotrophic lateral sclerosis (ALS)—a form of motor neuron disease.

5 Mar 2021

Genomics study examines the impact of COVID-19 on care homes

Care homes are at high risk of experiencing outbreaks of COVID-19, the disease caused by SARS-CoV-2. Older people and those affected by heart disease, respiratory disease and type 2 diabetes - all of which increase with age - are at greatest risk of severe disease and even death, making the care home population especially vulnerable.

4 Mar 2021

New software tool enables swift analysis of datasets generated from single-cell sequencing

A new software tool allows researchers to quickly query datasets generated from single-cell sequencing. Users can identify which cell types any combination of genes are active in.

4 Mar 2021

Researchers find effective combination of therapies for managing mitochondrial disease

Researchers have demonstrated how one combination of therapies may be beneficial for patients with mitochondrial respiratory chain disorders.

3 Mar 2021

Automated next generation sequencing platform can accurately screen thousands for COVID-19

A robotics platform designed by researchers to screen many COVID-19 samples at once has the potential to revolutionize how labs track the spread of viruses.

From University of Toronto 3 Mar 2021

New technique reveals the tricks that cancer cells use to avoid immunotherapies

By harnessing the immune system against cancer, immunotherapies have revolutionized the way some types of cancer are treated. But most patients--across cancer types--do not respond, and in most cases, scientists are at a loss as to why.

2 Mar 2021

UChicago-based team shares new details about Genomic Data Commons

The National Cancer Institute's Genomic Data Commons (GDC), launched in 2016 by then-Vice President Joseph Biden and hosted at the University of Chicago, has become one of the largest and most widely used resources in cancer genomics, with more than 3.3 petabytes of data from more than 65 projects and over 84,000 anonymized patient cases, serving more than 50,000 unique users each month.

1 Mar 2021

Researchers identify gene variant associated with childhood asthma

Researchers at Henry Ford Health System, as part of a national asthma collaborative, have identified a gene variant associated with childhood asthma that underscores the importance of including diverse patient populations in research studies.

1 Mar 2021

Increased levels of OAS1 protein may reduce the severity of COVID-19

Researchers at the Lady Davis Institute (LDI) at the Jewish General Hospital have discovered that increased levels of the protein OAS1 are associated with reduced mortality and less severe disease requiring ventilation among patients with COVID-19.

1 Mar 2021

Scientists map previously unknown metabolic pathways to produce memory T cell

Immunologists have plotted a previously unfamiliar biological pathway through which the immune system produces T cells that destroy viruses.

26 Feb 2021

Complexity of melodies in healthy infants increases across first six months

In the process of developing language, the melody patterns that emerge in infants' vocalisations are a very important first step.

25 Feb 2021

Genes inherited from parents are responsible for severe COVID-19

For the first time, scientists have discovered the genetic predisposition of severe COVID-19 disease.

24 Feb 2021

Machine learning algorithm helps differentiate benign and premalignant colorectal polyps

A machine learning algorithm helps accurately differentiate benign and premalignant colorectal polyps on CT colonography scans, according to a study published in the journal Radiology.

24 Feb 2021

Study provides new information on occurrence of DVL2 gene defect in dogs

A recent genetic study at the University of Helsinki provides new information on the occurrence of a DVL2 gene defect associated with a screw tail and its relevance to canine constitution and health.

24 Feb 2021

How is climate change affecting the allergy season?

AZoLifeSciences speaks to Professor William Anderegg about his latest research into climate change and how it is affecting the allergy season.

From The University of Utah 23 Feb 2021

Regular caffeine intake can change gray matter of the brain

Coffee, cola, or an energy drink: caffeine is the world's most widely consumed psychoactive substance. Researchers from the University of Basel have now shown in a study that regular caffeine intake can change the gray matter of the brain. However, the effect appears to be temporary.

17 Feb 2021

Innovative system allows complete study of SARS-CoV-2 mutant spectrum by ultrasequencing

Researchers have designed a program that allows the complete study of the SARS-CoV-2 mutant spectrum by ultrasequencing.

15 Feb 2021

Electrochemical sensor for rapid detection of multiple sepsis biomarkers in whole blood

Many life-threatening medical conditions, such as sepsis, which is triggered by blood-borne pathogens, cannot be detected accurately and quickly enough to initiate the right course of treatment.

15 Feb 2021

Hospital News and Research

Virtual clinical trials could transform the development of new drugs

SARS-CoV-2 can make itself unrecognizable to immune response by T-killer cells through mutations

Study reveals process behind key cellular change in amyotrophic lateral sclerosis

Genomics study examines the impact of COVID-19 on care homes

New software tool enables swift analysis of datasets generated from single-cell sequencing

Researchers find effective combination of therapies for managing mitochondrial disease

Automated next generation sequencing platform can accurately screen thousands for COVID-19

New technique reveals the tricks that cancer cells use to avoid immunotherapies

UChicago-based team shares new details about Genomic Data Commons

Researchers identify gene variant associated with childhood asthma

Increased levels of OAS1 protein may reduce the severity of COVID-19

Scientists map previously unknown metabolic pathways to produce memory T cell

Complexity of melodies in healthy infants increases across first six months

Genes inherited from parents are responsible for severe COVID-19

Machine learning algorithm helps differentiate benign and premalignant colorectal polyps

Study provides new information on occurrence of DVL2 gene defect in dogs

How is climate change affecting the allergy season?

Regular caffeine intake can change gray matter of the brain

Innovative system allows complete study of SARS-CoV-2 mutant spectrum by ultrasequencing

Electrochemical sensor for rapid detection of multiple sepsis biomarkers in whole blood

Driving Support for Pharmaceutical Testing Through Continuous Innovation

From Memory to Metaplasticity: Unraveling the Brain's Secrets

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

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