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Machine learning can increase effectiveness of drug repurposing for psychiatric disorders

Artificial intelligence can increase the effectiveness of drug repositioning or repurposing research, according to a study published in Translational Psychiatry.

4 Aug 2020

New light-based, cost-effective method to synthesize multisubstituted chemicals

A team of researchers from Japan has demonstrated a light-based reaction that yields high numbers of the base chemical component required to produce bioactive compounds used in common industry products.

4 Aug 2020

Newly discovered biomarkers predict response to immunotherapy in Type 1 diabetes

Scientists at UCL have discovered new biomarkers, which may identify those people with Type 1 diabetes who would benefit from the immunotherapy drug Abatacept, a finding which could eventually help thousands manage the disease more effectively.

From University College London 4 Aug 2020

Identifying a new genetic cause of inherited neuropathy

Inherited mutations in a gene that keeps nerve cells intact were shown, for the first time, to be a driver of neuropathy known as Charcot-Marie-Tooth disease.

4 Aug 2020

How sweet-taste perception changes with age

Compared with adults, children are less sensitive to the sweet taste and need 40% more sucrose for them to detect the taste of sugar, a new study found.

4 Aug 2020

Blind spots of soil biodiversity

Soils harbor a substantial part of biodiversity, yet data on the patterns and processes taking place below ground does not represent all relevant ecosystems.

4 Aug 2020

Cannabinoids may affect activity of other pharmaceuticals

Cannabinoid-containing products may alter the effects of some prescription drugs, according to Penn State College of Medicine researchers.

4 Aug 2020

Old part of immune system may influence severity of COVID-19

One of the immune system's oldest branches may be influencing the severity of COVID disease, according to a new study from researchers.

4 Aug 2020

Detecting rare circulating tumor cells

Metastasis - the development of tumor growth at a secondary site - is responsible for the majority of cancer-related deaths.

4 Aug 2020

Researchers develop CAR-T cell therapy based on TCR signal transduction

The T cell receptor (TCR) is a key receptor that is responsible for detecting tumor antigens in T cells.

4 Aug 2020

New study can help develop longevity-promoting drugs

Scientists have successfully dialed up and down the lifespan of creatures by changing the activity of proteins present in roundworm cells.

4 Aug 2020

The sustainability of the Indian sugar industry

Generations of political support for sugar cultivation have helped India become the second-largest producer of sugar worldwide.

3 Aug 2020

Hudsonalpha researchers help elucidate functional elements of the genome

Although the Human Genome Project sequenced a nearly-complete human genome almost 20 years ago, only about two percent of the genes in the human genome have been extensively studied and identified as protein-coding genes. Proteins form the basis of living tissues and play a central role in biological processes.

3 Aug 2020

EcoBuilder game aims to crowdsource solutions for unsolved ecological puzzles

EcoBuilder, which is downloadable now on smartphones and tablets, teaches players how ecosystems work and aims to crowdsource solutions to unsolved ecological puzzles.

3 Aug 2020

Biocrusts critical for supporting the world's shrinking water supplies

A global meta-analysis led by UNSW scientists shows tiny organisms that cover desert soils - so-called biocrusts - are critically important for supporting the world's shrinking water supplies.

From The University of New South Wales (UNSW) 3 Aug 2020

Chemical analysis provides new explanation for dramatic period of global cooling

Scientists have long known the earth cooled dramatically about 13,000 years ago, dropping temperatures by about 3 degrees Centigrade.

3 Aug 2020

Extreme temperatures adversely impact coral reef fish biodiversity and productivity

As global warming continues to escalate, there are lasting implications to consider, including the changes to biological communities in vital habitats such as coral reefs.

3 Aug 2020

Scientists develop a novel approach to synthesize three-dimensional nanocarbons

A team of scientists led by Kenichiro Itami, Professor and Director of the Institute of Transformative Bio-Molecules (WPI-ITbM), has developed a new method for the synthesis of three-dimensional nanocarbons with the potential to advance materials science.

3 Aug 2020

Konstanz biologists win Ursula M. Händel Animal Welfare Prize

Marcel Leist, Professor of In-Vitro Toxicology and Biomedicine at the University of Konstanz, and Thomas Hartung, Professor of Environmental Health Sciences at the University of Konstanz and Doerenkamp-Zbinden Chair of Evidence-Based Toxicology at Johns Hopkins Bloomberg School of Public Health in Baltimore, have been awarded the Ursula M. Händel Animal Welfare Prize 2020 of the German Research Foundation.

3 Aug 2020

'Little brain' contains almost 80% of the cerebral cortex’s surface area

When we say someone has a quick mind, it may be in part thanks to our expanded cerebellum that distinguishes human brains from those of macaque monkeys, for example.

3 Aug 2020