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Lipe Gene Plays Pivotal Role in Retinal Health, Study Finds

UT Southwestern Medical Center researchers have identified a gene called Lipe that appears to be pivotal to retinal health, with mutations spurring immune activation and retinal degeneration.

12 Jul 2023

New Insights Into How Genes Are Activated

Genetic information contained within DNA has to be read by specific proteins that enable the process of gene activation to begin – but in many cases, these proteins can't access their targets because DNA strands are bundled up to control what genes are used in the wide range of different cell types.

12 Jul 2023

Whole Genome Sequencing More Effective Than Targeted Gene Sequencing in Detecting Genetic Disorders

A new national study, led by researchers at Tufts Medical Center in Boston, has found whole genome sequencing (WGS) to be nearly twice as effective as a targeted gene sequencing test at identifying abnormalities responsible for genetic disorders in newborns and infants.

12 Jul 2023

AMP Releases CYP3A4 and CYP3A5 Genotyping Assay Recommendations

The Association for Molecular Pathology (AMP), the world’s leading professional society for molecular diagnostics, released consensus recommendations today to aid in the design and validation of clinical CYP3A4 and CYP3A5 genotyping assays, encourage standardization of testing across labs, and better patient care.

11 Jul 2023

T cells are Sensitive to Genetic Disturbances Within Mitochondrial Power Plants

All cells have their own power plants, called mitochondria. There are often more than 100 mitochondria per cell and each possesses their own genome, which in turn contains genes responsible for energy production.

7 Jul 2023

USDA Funds Texas A&M AgriLife Research to Develop “Holy Grail” of Tomatoes

The U.S. Department of Agriculture has funded a new Texas A&M AgriLife Research project expected to bring researchers even closer to developing the "holy grail" of tomatoes.

7 Jul 2023

Synthetically Constructed Minimal Cell Shows That Life Finds a Way

"Listen, if there's one thing the history of evolution has taught us is that life will not be contained. Life breaks free.

6 Jul 2023

Study Uncovers Candidate Genes That may Drive Inflammatory Bowel Disease

A study of the genetic variation that makes mice more susceptible to bowel inflammation after a high-fat diet has identified candidate genes which may drive inflammatory bowel disease (IBD) in humans.

6 Jul 2023

Negative Modulation of Arabidopsis Salinity Tolerance by CONSTANS Protein

Arabidopsis (Arabidopsis thaliana)’s photoperiodically controlled flowering and circadian pathways are primarily regulated by CONSTANS (CO), a well-known B-box family member.

5 Jul 2023

6mA Modification Genomic Distribution and Evolutionary Patterns in Plants

One of the epigenetic alterations is the amino acid N6-methyladenine (6mA). Although 6mA and 5-methylcytosine (5mC) were both found at the same time, eukaryotes have only lately begun to pay attention to it, primarily because of the limits of detection technologies.

5 Jul 2023

Gut Microbes Could Be Harnessed to Block Mercury Absorption

New research by a team at Pennsylvania State University suggests that microbes in the human gut could be harnessed to block absorption of toxic metals like mercury and help the body absorb useful nutritional ones, like iron.

5 Jul 2023

Host Genetics Affects Composition of Switchgrass Root Microbiome

Plants provide a home for a wide diversity of microbes, especially in their roots. In turn, these communities can provide important benefits for the host.

5 Jul 2023

Deep Learning Model Accurately Predicts RNA-Targeting CRISPR Activity

According to new research published in Nature Biotechnology, artificial intelligence can predict on- and off-target behavior of CRISPR tools that target RNA rather than DNA.

5 Jul 2023

Camena Bioscience Closes $10m Series A Financing as Demand for DNA Synthesis Technology Increases

Camena Bioscience, a synthetic biology company providing genes to the pharmaceutical and biotechnology industries, today announced it has closed a $10m Series A financing round, led by Mercia.

4 Jul 2023

Trim24 Limits the Ability of p53 to Function as a Tumor Suppressor

The tumor suppressor protein p53 has been nicknamed the “guardian of the genome” because it safeguards the DNA from long-term damage or stress by controlling the expression of numerous genes involved in DNA repair, cell division, and cell death.

3 Jul 2023

New AI Tool Tracks Complex Fruit Fly Behavior

What is the easiest way to know if a fruit fly is hungry? Ask a computer.

3 Jul 2023

Tiny Sea Creature Offers Insights into Healing and Aging

National Institutes of Health researchers and their collaborators revealed fresh insights into healing and aging by studying how a small marine creature regenerates a completely new body from only its mouth.

3 Jul 2023

Ancient Virus-Like Transposons Found to Mediate Horizontal Gene Transfer in Worms

Scientists have known for decades that genes can be transferred from one species to another, both in animals and plants.

30 Jun 2023

Identifying the Genetic Variant That Increases Disease Severity in MS

Research of over 22,000 patients with multiple sclerosis (MS) has for the first time discovered a genetic variant linked with speedier progression of the disease, a buildup of disability that can deprive patients of their mobility and independence over time.

29 Jun 2023

The First Programmable RNA-Guided System in Eukaryotes Uncovered

Feng Zhang of the Broad Institute at MIT and Harvard and the McGovern Institute for Brain Research at MIT headed a team of researchers who discovered the first programmable RNA-guided mechanism in eukaryotes, which include fungi, plants, and animals.

29 Jun 2023