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Study Unveils Dual Role of 7-DHC in Ferroptosis and Cancer Cell Survival

Cell death is fundamental to life and, thus, healthy aging. In the realm of cellular biology, ferroptosis (a form of programmed cell death) has emerged not only as a focal point of research for its potential in eliminating cancer cells, but also its role in a plethora of other diseases, including neurodegenerative diseases such as Alzheimer's disease, eye diseases such as Retinitis pigmentosa and age-related macular degeneration, as well as ischemia, cardiovascular disease, liver disease, acute kidney injury and inflammation.

2 Feb 2024

Breaking Barriers in Life Sciences: eLabNext and Promega’s New Alliance for Smarter Digital Lab Management

eLabNext (an Eppendorf Group Company), the provider of a Digital Lab Platform with lab inventory management system (LIMS), electronic lab notebook (ELN), and artificial intelligence (AI)/machine learning (ML) solutions for life science laboratories, and Promega Corporation (Promega), a global leader in innovative technologies, tools, and technologies for the life science industry, announced a collaboration today to make Promega’s standard operating procedures (SOPs) readily accessible through the eLabNext’s eLabMarketplace.

1 Feb 2024

New Research Finds Placenta Cells May Lower Blood Pressure

Scientists from La Trobe University and the Hudson Institute have demonstrated that cells from placentas could have therapeutic benefits for patients suffering from high blood pressure.

1 Feb 2024

Enhanc3D Genomics Appoints Dr Daniel Turner as Chief Scientific Officer

Enhanc3D Genomics, a company developing disruptive technologies to unlock the 3D spatial genome for target and biomarker discovery, today announced the appointment of Dr Daniel Turner as Chief Scientific Officer (CSO). Dan’s deep expertise in genomics technology development and commercialisation will be key to achieving the next phase of Enhanc3D Genomics’ growth.

1 Feb 2024

Promising Drug Offers Hope for Overcoming Resistance to Protein Degraders

Protein degraders, a novel approach in drug discovery, show promise to tackle diseases previously thought to be untreatable.

31 Jan 2024

Scientists Create "Immunologically Silent" DNA Vaccine for Potent Virus Defense

Using a virus-like delivery particle made from DNA, researchers from MIT and the Ragon Institute of MGH, MIT, and Harvard have created a vaccine that can induce a strong antibody response against SARS-CoV-2.

31 Jan 2024

Gene Therapy Can Interrupt the Progression of Deadly Inherited Heart Condition

A new study in mice shows that replacement of a dysfunctional gene could prolong survival in some people with arrhythmogenic right ventricular cardiomyopathy (ARVC), a rare inherited disorder in which the muscular walls of the heart progressively weaken and put patients at risk of dangerous irregular heartbeats.

31 Jan 2024

Gut Bacteria Shape Our Defense Against Respiratory Viral Infections

The composition of microbiota found in the gut influences how susceptible mice are to respiratory virus infections and the severity of these infections, according to researchers from the Center for Translational Antiviral Research in the Institute for Biomedical Sciences at Georgia State University.

31 Jan 2024

King’s Scientists Use Laundry Detergent Enzyme to Recycle Single-Use Plastics

Scientists at King’s College London have developed an innovative solution for recycling single-use bioplastics commonly used in disposable items such as coffee cups and food containers.

31 Jan 2024

Plant Protein Drives Textured Cell Growth in Lab-Grown Meat

Cultivated meat, or lab-grown meat, which is made of animal muscle and fat cells grown in a lab, has become a viable option as the world's population grows.

30 Jan 2024

NLRC5 Gene Reactivation Boosts Tumor-Killing Immunity

Every human cell has class I major histocompatibility complex (MHC) molecules on its surface, which are immune complexes. The immune system needs MHC class I molecules to identify and eradicate cancer.

30 Jan 2024

Scientists Unleash the Power of Calcium to Target and Destroy Tumor Cells

Calcium ions are essential for cells, but can be toxic in higher concentrations. A team of researchers has now designed and prepared a combination drug that kills tumor cells by modulating the calcium influx into the cell.

30 Jan 2024

SYCE2 Gene Variant Disrupts Alignment of Chromosomes, Potentially Leading to Pregnancy Loss

Scientists at deCODE genetics, a subsidiary of Amgen and their collaborators from Iceland, Denmark and USA published a study today in Nature Structural and Molecular Biology titled "Variant in the synaptonemal complex protein SYCE2 associates with pregnancy loss through effects on recombination".

30 Jan 2024

Asimov Launches LV Edge Packaging System to Optimize Lentivirus Production

Asimov, the synthetic biology company advancing the design and manufacture of therapeutics, today announced the launch of their LV Edge Packaging System, which improves the cost efficiency and reduces the supply chain risk of lentiviral production.

30 Jan 2024

Bio-Techne’s Advanced Cell Diagnostics (ACD) Sets New Standard in Spatial Biology with Protease-Free RNAscope Multiomics

Bio-Techne Corporation today announced that Advanced Cell Diagnostics (ACD), a Bio-Techne spatial biology brand, has set a new standard with the development of a next-generation, protease-free RNAscope spatial multiomics workflow.

From Bio-Techne 30 Jan 2024

How the Brain Controls its Cravings for Water and Salt

For terrestrial creatures, including humans, to survive, they must drink plenty of water and eat enough salt. Neural pathways comprising many brain regions intriguingly control both thirst and salt appetite.

29 Jan 2024

“Free-from-Tree” Production of Vaccine Component QS-21

For the first time, a valuable chemical extracted from the soapbark tree and utilized as a major component in vaccinations has been duplicated in a different plant host, providing the vaccine industry with hitherto unheard-of potential.

29 Jan 2024

Accelerating the Approval Process for Cultivated Meat

Technological advancements are making cellular agriculture the production of meat from cells grown in bioreactors as opposed to gathered from farm animals a more attractive option for the food sector.

29 Jan 2024

Promoter Mutations and Their Association with Autism Risk

The RIKEN Center for Brain Science (CBS) employed genome mutation analysis to investigate the genetics of autism spectrum disorder (ASD) in people and their families. They found that the way a certain type of genetic mutation contributes to the illness differs from that of ordinary mutations.

29 Jan 2024

Study Sheds Light on a Decades-Long Mystery About How Retinal Photoreceptors Work

Working with mammalian retinal cells, neuroscientists at Johns Hopkins Medicine have shown that, unlike most light-sensing cells (photoreceptors) in the retina, one special type uses two different pathways at the same time to transmit electrical "vision" signals to the brain.

27 Jan 2024