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Understanding Lactate's Role in Energy Metabolism

As a student competing in track and field at his Parlier high school, Robert Leija was obsessed with how to improve his performance and, in particular, prevent the buildup of lactic acid in his muscles during training.

16 May 2024

Genetic Analysis Sheds Light on the Role of Ribosomal DNA Copy Number in Inflammation and Disease

Ribosomal DNA (rDNA) is present in hundreds of copies in the genome, but has not previously been part of genetic analyses.

16 May 2024

Runt Transcription Factor Links Regeneration and Photosynthesis in Marine Worm-Algae Symbiosis

Many organisms are far more complex than just a single species. Humans, for example, are full of a variety of microbes.

16 May 2024

Discovery of Novel Adrenal Cell Type Linked to Monogamy in Oldfield Mice

What makes the oldfield mouse steadfastly monogamous throughout its life while its closest rodent relatives are promiscuous? The answer may be a previously unknown hormone-generating cell, according to a new study published online today in Nature from scientists at Columbia's Zuckerman Institute.

16 May 2024

Glycosylation and its Role in Human Health and Disease

The current understanding of glycosylation genetics in mammals and the consequences of mutations that impact glycosylation.

16 May 2024

Machine Learning Program Offers Insights Into Promoter Sequences and Transcription

A team led by researchers at UT Southwestern Medical Center developed deep learning models to identify a simple set of rules that govern the activity of promoters – regions of DNA that initiate the process by which genes produce proteins.

15 May 2024

Unlocking the Genetics of Coral-Destroying Crown-of-Thorns Starfish

Scientists are one step closer to combatting coral-destroying crown-of-thorns starfish, following a University of Queensland study into the pest's genetics.

15 May 2024

Transcriptomic Analysis Reveals Age-Dependent Gene Expression Patterns in Mouse Sweat Glands

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, Issue 8, entitled, "Characterization of age-associated gene expression changes in mouse sweat glands."

15 May 2024

Unlocking the Secrets of Childhood Cancer Genetics

Scientists have revealed a fresh insight into the genetic pathway of childhood cancer, providing new potential for personalized treatment.

15 May 2024

Researchers Uncover More Genes Linked to Clonal Hematopoiesis

Researchers have identified 17 more genes that cause the aberrant proliferation of blood cells with mutations as humans age. The results were published in the journal Nature Genetics.

15 May 2024

New Insights Into Centromere Structure: Two Subdomains Revealed

Researchers from the Kops group in collaboration with researchers from the University of Edinburgh, made a surprising new discovery in the structure of the centromere, a structure that is involved in ensuring that chromosomes are segregated properly when a cell divides.

14 May 2024

Unraveling the IS Transposition-Mediated Anti-Phage Mechanism in Mycobacteria

This study is led by Prof. Zheng-Guo He (Guangxi Research Center for Microbial and Enzyme Engineering Technology, College of Life Science and Technology, Guangxi University,China).

14 May 2024

Rice Study Sheds Light on Pseudogene Dynamics

Rice University's Peter Wolynes and his research team have unveiled a breakthrough in understanding how specific genetic sequences, known as pseudogenes, evolve.

14 May 2024

Single-Molecule Study Reveals Unexpected Role of Protein Stiffness in Nuclear Transport

The degree of softness or rigidity in specific regions of proteins can affect how quickly or slowly those proteins enter the nucleus, according to research from the Francis Crick Institute and King's College London.

14 May 2024

Synthetic Anti-Clotting Agent Derived from Bloodsucking Organisms Saliva

Ticks, mosquitoes, and leeches are endowed by nature with a rapid method of preventing blood clotting while they feed on their host.

14 May 2024

MUSIC Map Uncovers Accelerated Aging in Brain Cells Linked to Alzheimer’s

Researchers observed sex-specific differences in the aging process of certain brain cells.

14 May 2024

Harnessing High-Performance Computing to Unravel the Emergence of Novel Viruses

Suddenly they appear and - like the SARS-CoV-2 coronavirus - can trigger major epidemics: Viruses that nobody had on their radar.

14 May 2024

Glutamate tRNA Fragments Play Key Role in Brain Aging and Alzheimer's Disease

A significant research paper published in the journal Cell Metabolism by the team of Prof. LIU Qiang at the University of Science and Technology of China (USTC) reveals the critical role of glutamate tRNA fragments in brain aging and Alzheimer's disease.

14 May 2024

Metrovate is Developing Precision Biostimulants for More Effective and Sustainable Farming Outcomes

Metrovate has announced a $1 million capital raise by Sprout Agritech LP to fund the development of New Zealand’s first precision biostimulant for agriculture.

From Metrovate 14 May 2024

Study Reveals the Surprising Role of Spliceosomes in Introns' Journey

Although you may not appreciate them, or have even heard of them, throughout your body, countless microscopic machines called spliceosomes are hard at work.

13 May 2024