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Targeting Long-read RNA Sequencing with Low-Cost Technology

Researchers at the Children’s Hospital of Philadelphia (CHOP) have created a flexible and affordable approach for targeted sequencing of full-length RNA molecules, which might hasten the development of novel diagnostics and therapies.

16 Aug 2023

Researchers Identify Key Cells Involved in the Process of Cartilage Regeneration in Lizards

A team of researchers from the Keck School of Medicine of USC have published the first detailed description of the interplay between two cell types that allow lizards to regenerate their tails.

11 Aug 2023

New Microscope Combined with AI Software to Identify Malaria Parasites in Blood Samples

Each year, more than 200 million people fall sick with malaria and more than half a million of these infections lead to death.

11 Aug 2023

New Mechanism Regulating Tumor Growth in the Skeleton Identified

Tumor cells are known to be fickle sleeper agents, often lying dormant in distant tissues for years before reactivating and forming metastasis. Numerous factors have been studied to understand why the activation occurs, from cells and molecules to other components in the so-called tissue microenvironment.

11 Aug 2023

Researchers Lead Innovative Studies on Mammalian Aging and Life Span

Scientists at UCLA David Geffen School of Medicine and UCLA Health led an international research team that published two articles detailing changes in DNA – changes that researchers found are shared by humans and other mammals throughout history and are associated with life span and numerous other traits.

11 Aug 2023

Gene Therapy Prevents Progression of Kidney Disease in Children

Researchers at the University of Bristol have made a remarkable step forward in finding a potential cure for a type of childhood kidney disease.

11 Aug 2023

Persons With Type 2 Diabetes are More Likely to Experience Changes in Brain Structure

The longer a person has type 2 diabetes, the more likely they may be to experience changes in brain structure, a Michigan Medicine study finds.

11 Aug 2023

Study Links Adenovirus Infection With a Rare Blood Clotting Disorder

Platelets, or thrombocytes, are specialized cellular fragments that form blood clots when we get scrapes and traumatic injuries. Viral infections, autoimmune disease, and other conditions can cause platelet levels to drop throughout the body, termed thrombocytopenia.

11 Aug 2023

Linking Alzheimer's Genetic Marker and Higher Female Fertility

The Apolipoprotein-ε4 (APOE-ε4) allele has been linked to an increased risk for several types of diseases in aging populations, particularly Alzheimer’s and cardiovascular disease.

10 Aug 2023

Unique Molecular Structure Has Effects on Age-Related Diseases

The mitochondria, sometimes known as the “powerhouses of the cell,” are widely recognized for their function as energy producers, but these organelles are also essential for preserving general health.

8 Aug 2023

Detection of Mutations in Children with Brain Tumors

Uppsala University researchers have devised a novel approach for detecting mutations in pediatric brain cancers.

8 Aug 2023

Researchers Elucidate STING Protein's New Role in Immune Defense

A signaling protein known as STING is a critical player in the human immune system, detecting signs of danger within cells and then activating a variety of defense mechanisms.

7 Aug 2023

Reptile Conservation Could Benefit From New Range of Cell Lines

The creation of the first wide variety of reptile cell lines is highlighted in a new scientific study that was published in the journal Microorganisms.

7 Aug 2023

RNA Modification in Driving Pancreatic Cancer Growth

RNA molecules can undergo chemical changes like m6A, which can have a significant influence on gene expression and affect several aspects of cancer development and progression

7 Aug 2023

GEMINI Test Uses Genome-Wide Sequencing to Detect Cancer

Novel blood testing technology being developed by researchers at the Johns Hopkins Kimmel Cancer Center that combines genome-wide sequencing of single molecules of DNA shed from tumors and machine learning may allow earlier detection of lung and other cancers.

7 Aug 2023

New Insights Into How T Cells Become Exhausted in Cancer

Immune system T cells that should be able to kill cancer cells become dysfunctional or "exhausted" within hours of encountering a tumor, according to a study reported Aug. 3 in Nature Immunology.

7 Aug 2023

Elephants may Hold Secrets to Long Life

Indiana University researcher Daniella Chusyd is studying human aging in an unlikely way: through elephants.

7 Aug 2023

Determining a Network of Cellular Programs Controlling Human Cancers

A Ludwig Cancer Research study has identified a pair of genes whose expression by a type of immune cell within tumors is predictive of outcomes for cancer patients and is linked to a vast network of gene expression programs, engaged by multiple cell types in the tumor microenvironment, that control human cancers.

4 Aug 2023

Study Shows How Sensory Neurons Control Gastrointestinal Tracts

Gastrointestinal and digestive issues impact roughly 3 million people across the United States alone, and that number is growing.

4 Aug 2023

Gut Hormone Plays a Vital Role in Maintaining the Balance of Fungi in the Digestive System of Mammals

Peptide YY (PYY), a hormone produced by gut endocrine cells that was already known to control appetite, also plays an important role in maintaining the balance of fungi in the digestive system of mammals, according to new research from the University of Chicago.

4 Aug 2023