Hospital News and Research

RSS

Novel computational approach helps find genetic causes of severe childhood brain disorders

A team of researchers at Children's Hospital of Philadelphia affiliated with the CHOP Epilepsy Neurogenetics Initiative (ENGIN) have combined clinical information with large-scale genomic data to successfully link characteristic presentations of childhood epilepsies with specific genetic variants.

27 Aug 2020

Scientists document communication pathways in SARS-CoV-2 infected human cells

In the transmission of signals within the cell which, for example, stimulate cell growth or trigger metabolic processes, phosphate groups play an important biochemical role.

26 Aug 2020

Scientists identify key genes that influence cancer treatment success

Radiotherapy is a cornerstone of today's cancer treatment. About half of all people suffering from cancer with a so-called radiotherapy.

26 Aug 2020

New syringe technology for subcutaneous injection of viscous formulations

MIT researchers have developed a simple, low-cost technology to administer powerful drug formulations that are too viscous to be injected using conventional medical syringes.

25 Aug 2020

New approach could slow colon cancer metastasis

When cancer metastasizes and spreads throughout the body, it can severely change the prognosis of the disease. It is estimated that metastasis is responsible for 90 percent of cancer deaths.

25 Aug 2020

Rare disorder of fat metabolism can cause chronic hyperreaction of the immune system

A congenital disorder of the fat metabolism can apparently cause chronic hyperreaction of the immune system. This is the conclusion reached by researchers from the University of Bonn in a recent study.

25 Aug 2020

Lipid-based nanoparticles can help treat genetic disorders

Introducing genetic material into the body to treat diseases can work, but making sure that those materials are safely sent to the right location is complicated.

24 Aug 2020

New bioluminescent reporter tracks DNA double stranded break repair in cells

A new bioluminescent reporter that tracks DNA double stranded break (DSB) repair in cells has been developed by researchers from Massachusetts General Hospital (MGH) and the Academia Sinica in Taiwan.

24 Aug 2020

Eliminating tumors with engineered ‘off-the-shelf’ therapeutic T cells

Personalized cancer treatments are no longer just options of the future. In the past few years, researchers have made significant progress in 'teaching' the body's immune T cells to recognize and kill specific cancer cells, and human clinical trials have shown that this approach can successfully eliminate tumors

21 Aug 2020

Exposure to air pollution may increase risk of cardiometabolic diseases

Air pollution is the world's leading environmental risk factor, and causes more than nine million deaths per year.

21 Aug 2020

Master regulator genes of asthma identified

Researchers identify master regulator genes of asthma, provide new path forward in the study of asthma and the development of novel therapies.

21 Aug 2020

Genetic background influences cancer risk in individuals with single-gene variants

Life can change dramatically when someone learns they are genetically predisposed to a disease, such as a condition called familial hypercholesterolemia, where a mutated gene can lead to elevated cholesterol and increased risk for a premature heart attack.

21 Aug 2020

Cytokine storms in COVID-19 patients may prevent the development of long-term immunity

Shiv Pillai, MD, Ph.D., investigator in the Ragon Institute of MGH, MIT and Harvard and professor at Harvard Medical School (HMS), recently published a paper in Cell showing that that high levels of some cytokines seen in COVID-19 patients, as part of a cytokine storm, may prevent the development of long-term immunity to SARS-CoV-2, the virus that causes COVID-19.

20 Aug 2020

Female reproductive tract capable of mediating post-mating sexual selection

The female reproductive tract has the final say in human mate choice, according to new research from the University of Eastern Finland.

20 Aug 2020

Study reveals a mechanism for lower-quality immune response in patients with severe COVID-19

The release of massive amounts of proteins called cytokines can lead to some of the most severe symptoms of COVID-19.

From Harvard Medical School 20 Aug 2020

Greater gut microbial diversity in kidney cancer patients linked to better treatment outcomes

Physicians at City of Hope, working in collaboration with scientists at Translational Genomics Research Institute (TGen), have found that greater gut microbial diversity in patients with metastatic kidney cancer is associated with better treatment outcomes on Food and Drug Administration-approved immunotherapy regimens.

20 Aug 2020

Hospital News and Research

Novel computational approach helps find genetic causes of severe childhood brain disorders

Scientists document communication pathways in SARS-CoV-2 infected human cells

Scientists identify key genes that influence cancer treatment success

New syringe technology for subcutaneous injection of viscous formulations

New approach could slow colon cancer metastasis

Rare disorder of fat metabolism can cause chronic hyperreaction of the immune system

Lipid-based nanoparticles can help treat genetic disorders

New bioluminescent reporter tracks DNA double stranded break repair in cells

Eliminating tumors with engineered ‘off-the-shelf’ therapeutic T cells

Exposure to air pollution may increase risk of cardiometabolic diseases

Master regulator genes of asthma identified

Genetic background influences cancer risk in individuals with single-gene variants

Cytokine storms in COVID-19 patients may prevent the development of long-term immunity

Female reproductive tract capable of mediating post-mating sexual selection

Study reveals a mechanism for lower-quality immune response in patients with severe COVID-19

Greater gut microbial diversity in kidney cancer patients linked to better treatment outcomes

Elevated levels of heart failure marker increase risk for diabetes-related complications

Shielded stem cells can improve heart healing

RNA-based therapeutic approach could be used to cure hereditary diseases

Scientists identify complex enzyme that protects cells from constant DNA damage

Driving Support for Pharmaceutical Testing Through Continuous Innovation

From Memory to Metaplasticity: Unraveling the Brain's Secrets

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

Latest in Genomics