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Refreshers develop new DNA sequencing method

An international research team headed by Michal Hocek of the Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences (IOCB Prague) and Charles University and Ciara K. O'Sullivan of Universitat Rovira i Virgili (URV) in Spain have developed a novel method for labeling DNA, which in the future can be used for sequencing DNA by means of electrochemical detection.

18 May 2021

Researchers identify the biosynthesis mechanism of new DNA nucleobases

DNA is made up of nucleobases, which are depicted by the letters G, A, T, and C. They are the foundation of the genetic code.

From Institut Pasteur 13 May 2021

Highly efficient method to identify the genetic “switches” that control gene expression

Scientists have created a high-throughput method to help explain and regulate gene expression for the treatment of diseases like beta-thalassemia and sickle cell disease.

7 May 2021

Researchers sequence genome of raccoon dogs that are reservoir hosts for coronaviruses

For the first time, a research team has sequenced the genome of a raccoon dog. Genetic data now supports the animal’s ability to spread SARS-CoV-2.

6 May 2021

New study classifies urban wild meat traffickers and sellers in Africa

A new study classifies different types of wildlife traffickers and sellers in two of Central Africa's growing urban centers, providing new insight into the poorly understood urban illegal wildlife trade.

20 Apr 2021

Ebola virus protein changes shape by using human RNA

The human genome contains the instructions to make tens of thousands of proteins. Each protein folds into a precise shape--and biologists are taught that defined shape dictates the protein's destined function. Tens of thousands of singular shapes drive the tens of thousands of needed functions.

15 Apr 2021

Researchers find large quantities of previously undetected PFAS

Researchers from the Harvard John A. Paulson School of Engineering and Applied Sciences (SEAS) found large quantities of previously undetectable compounds from the family of chemicals known as PFAS in six watersheds on Cape Cod using a new method to quantify and identify PFAS compounds.

8 Mar 2021

Sufficient rest during holidays restores functions associated with DNA regulation

According to a recent study, sufficient rest during vacation time restored functions linked to DNA regulation in shift workers deprived of sleep.

23 Feb 2021

Advanced explainable AI to solve regulatory instructions encoded in DNA

Researchers at the Stowers Institute for Medical Research, in collaboration with colleagues at Stanford University and Technical University of Munich have developed advanced explainable artificial intelligence (AI) in a technical tour de force to decipher regulatory instructions encoded in DNA.

19 Feb 2021

New statistical study shows how pairs of cancer cells interact

One of the fundamental principles of biology is the fact that cells are motile and make contact with one another.

17 Feb 2021

DNA-editing technique used to extend lifespan of mice with progeria

Researchers have successfully used a DNA-editing technique to extend the lifespan of mice with the genetic variation associated with progeria, a rare genetic disease that causes extreme premature aging in children and can significantly shorten their life expectancy.

From National Human Genome Research Institute (NHGRI) 7 Jan 2021

Study may lead to new treatments for certain types of disease

Researchers at the Francis Crick Institute have found a new way to prevent some tumours from repairing their own DNA, a function that is essential for cancer cell survival. This discovery could lead to much needed new treatments for certain types of the disease.

17 Dec 2020

Olefins formed by light-driven catalyst can help produce drugs, agrochemicals

Taking a cue from light-sensing bacteria that live close to hot oceanic vents, synthetic chemists from Rice University have identified a mild process to produce useful hydrocarbons, called alkenes, or olefins.

11 Dec 2020

A non-physical method for generating random building blocks

True random numbers are required in fields as diverse as slot machines and data encryption. These numbers need to be truly random, such that they cannot even be predicted by people with detailed knowledge of the method used to generate them.

23 Nov 2020

Pancreatic cancer cells avert starvation by signaling to nerves, shows study

Pancreatic cancer cells avert starvation by signaling to nerves, which grow into dense tumors and secrete nutrients. This is the finding of a study with experiments in cancer cells, mice, and human tissue samples published online on November 2 in Cell.

3 Nov 2020

Researchers develop new approach that uses DNA-synthesizing biological enzyme

According to current estimates, the amount of data produced by humans and machines is rising at an exponential rate, with the digital universe doubling in size every two years.

19 Oct 2020

Researchers develop a new method for siRNA stabilization

In the gene controlling mechanism, known as RNA interference, the expression of particular genes is downregulated by siRNAs or endogenic microRNAs.

19 Oct 2020

New machine learning algorithms to analyze reams of RNA-based 'toehold' sequences

DNA and RNA have been compared to "instruction manuals" containing the information needed for living "machines" to operate.

7 Oct 2020

Climate change is a risk accelerator for several aspects of economy and society

It could be worth up to 8% of GDP per capita, exacerbate the differences between north and south, between society's rich and poor, as well as affect a number of Italy's strategic sectors: climate change is a risk accelerator for many aspects of both the economy and society.

24 Sep 2020

Study explains how epigenetic factors relate to aging

According to a study, headed by a psychologist at the University of California, genetic background may influence how people adapt to aging in late life.

20 Aug 2020