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Human Skin Map Gives ‘Recipe’ to Build Skin and Could Help Prevent Scarring

For the first time, researchers have created a single cell atlas of prenatal human skin to understand how skin forms, and what goes wrong in disease.

From Wellcome Sanger Institute 14 Oct 2024

UC San Diego and UC Berkeley Collaborate on Innovative Antibiotic Resistance Solution

University of California San Diego and University of California Berkeley researchers have been awarded up to $7 million from the Advanced Research Projects Agency for Health (ARPA-H) to conduct research under the PROTECT project -; Pro/Prebiotic Regulation for Optimized Treatment and Eradication of Clinical Threats.

14 Oct 2024

Metabolic Profiling of Lung-Resident NK Cells Reveals Novel Therapeutic Targets

Trinity College Dublin researchers, based at St James's Hospital have provided important insights into the behavior and metabolic function of a previously largely unknown, but crucial 'natural killer' (NK) immune cell resident in the lungs.

14 Oct 2024

New Research Examines the Role of Skeletal Stem Cells in Bone Growth and Regeneration

Researchers at UTHealth Houston have been awarded an $8.1 million grant by the National Institutes of Health (NIH) to examine skeletal stem cells as potential drivers of craniofacial bone diseases and deformities. The study is led by Noriaki Ono, DDS, PhD, associate professor of orthodontics, and diagnostic and biomedical sciences at UTHealth Houston School of Dentistry.

14 Oct 2024

Bacterial Gene Expression Drives the Evolution of Antibiotic Resistance

As strains of pathogens resistant to frontline antibiotics become more common worldwide, clinicians are more often turning to combination treatments that degrade this resistance as a first treatment option.

14 Oct 2024

Unveiling the Link Between Genetics, Stress, and Type 2 Diabetes

The cells in the human pancreas have a limit to how much stress they can withstand before degenerating.

10 Oct 2024

CAR-NKT Cells Show Promise in Overcoming Solid Tumor Barriers

Chimeric antigen receptor T-cell therapy (CAR-T) has shown significant promise in the treatment of blood malignancies in the fight against cancer.

8 Oct 2024

UNC Researchers Unveil CAR-NKT Therapy for Enhanced Antitumor Activity

In the fight against cancer, chimeric antigen receptor T cell (CAR-T) therapy has achieved notable success in treating blood cancers. However, it has been largely ineffective against solid tumors.

8 Oct 2024

Scientists Uncover Secrets of Circadian Rhythm Control

Scientists from Duke-NUS Medical School and the University of California, Santa Cruz, have discovered the secret to regulating our internal clock.

8 Oct 2024

Fighting Drug-Resistant TB with a Novel Antibiotic

A novel semi-synthetic molecule that produces significant activity against strains of Mycobacterium tuberculosis, including those that are resistant to drugs, can be generated from natural compounds according to a study published in the American Society for Microbiology journal Microbiology Spectrum.

4 Oct 2024

Zinc Inhibits Plasmid Transfer in Gut Microbes

Genes responsible for antimicrobial resistance (AMR) can spread from microbe to microbe through circular genetic material called plasmids, and this lateral transfer occurs in the gut. This week in Applied and Environmental Microbiology, researchers in Iowa report that the transmission of some AMR plasmids may be inhibited by a readily available source-;dietary zinc supplements.

4 Oct 2024

EPA-Funds Study on Antimicrobial Resistance in Wastewater and Agricultural Runoff

Aided by a $2.4 million grant from the Environmental Protection Agency, a team of University of Nebraska–Lincoln engineers and scientists is leading a multi-state effort to assess the potential threat to human health from antimicrobial-resistant pathogens spread via wastewater and agricultural runoff.

4 Oct 2024

Scientists Successfully Map the Entire Fruit Fly Brain

A team of scientists supported by the National Institutes of Health (NIH)'s The BRAIN Initiative, including Davi Bock, Ph.D., Associate Professor of Neurological Sciences at UVM's Robert Larner, M.D. College of Medicine, recently made a substantial advancement in neurobiological research by successfully mapping the entire brain of Drosophila melanogaster, more commonly known as the fruit fly.

3 Oct 2024

Unlocking the Mysteries of Repeat Expansion in Genetics

Research led by scientists at Queen Mary University of London is heralding in a new era for genetic sequencing and testing.

3 Oct 2024

Bipolar Disorder and Epilepsy Share Genetic Roots

A team of researchers from the Chinese Academy of Sciences has uncovered compelling evidence of a genetic link between bipolar disorder type I (BD-I) and epilepsy, potentially revolutionizing our understanding of these complex neuropsychiatric conditions.

1 Oct 2024

A Novel Genetic Inference Method for Detecting Rare Disease Variants

Undiagnosed cases of Long QT syndrome have been found, thanks to an inventive examination of shared genomic sequences, which is a sign of distant “relatedness” and can cause irregular heart rhythms, fainting, and sudden cardiac death.

30 Sep 2024

Huntington's Disease Protein Disrupts DNA Repair

Researchers at McMaster University have found that the mutated protein in Huntington's disease patients disrupts DNA repair as it should, which affects the capacity of brain cells to regenerate.

30 Sep 2024

Study Confirms Comparable Efficacy of Lamotrigine and Mexiletine in Muscle Channelopathy

The study, published in Lancet Neurology, detailed the "head-to-head" trial implemented by the researchers to test two drugs, mexiletine and lamotrigine, on people with the condition.

30 Sep 2024

The Role of Macrophages in Shaping the Inflammatory Environment in Rheumatoid Arthritis

Currently there are no cures for rheumatoid arthritis (RA) which affects 40,000 people in Ireland. The disease costs an estimated €20,000 per patient, per year with an overall cost to the health system of ~€544 million. Only 1 in 4 patients achieve remission and a significant proportion of patients have suboptimal responses or no response at all to current available therapies.

30 Sep 2024

Research Reveals How the Brain Encodes Time and Experiences at the Neuronal Level

A landmark study led by UCLA Health has begun to unravel one of the fundamental mysteries in neuroscience – how the human brain encodes and makes sense of the flow of time and experiences.

26 Sep 2024

Clinical News and Research

Human Skin Map Gives ‘Recipe’ to Build Skin and Could Help Prevent Scarring

UC San Diego and UC Berkeley Collaborate on Innovative Antibiotic Resistance Solution

Metabolic Profiling of Lung-Resident NK Cells Reveals Novel Therapeutic Targets

New Research Examines the Role of Skeletal Stem Cells in Bone Growth and Regeneration

Bacterial Gene Expression Drives the Evolution of Antibiotic Resistance

Unveiling the Link Between Genetics, Stress, and Type 2 Diabetes

CAR-NKT Cells Show Promise in Overcoming Solid Tumor Barriers

UNC Researchers Unveil CAR-NKT Therapy for Enhanced Antitumor Activity

Scientists Uncover Secrets of Circadian Rhythm Control

Fighting Drug-Resistant TB with a Novel Antibiotic

Zinc Inhibits Plasmid Transfer in Gut Microbes

EPA-Funds Study on Antimicrobial Resistance in Wastewater and Agricultural Runoff

Scientists Successfully Map the Entire Fruit Fly Brain

Unlocking the Mysteries of Repeat Expansion in Genetics

Bipolar Disorder and Epilepsy Share Genetic Roots

A Novel Genetic Inference Method for Detecting Rare Disease Variants

Huntington's Disease Protein Disrupts DNA Repair

Study Confirms Comparable Efficacy of Lamotrigine and Mexiletine in Muscle Channelopathy

The Role of Macrophages in Shaping the Inflammatory Environment in Rheumatoid Arthritis

Research Reveals How the Brain Encodes Time and Experiences at the Neuronal Level

Driving Support for Pharmaceutical Testing Through Continuous Innovation

From Memory to Metaplasticity: Unraveling the Brain's Secrets

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

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