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Ribosomal Fingerprints: A Novel Approach to Early Cancer Detection

Different types of cancer have unique molecular 'fingerprints' which are detectable in early stages of the disease and can be picked up with near-perfect accuracy by small, portable scanners in just a few hours, according to a study published today in the journal Molecular Cell.

11 Dec 2024

Genetic Mutation in the Inherited DNA Found to Drive Breast Cancer Metastasis

Ninety percent of cancer deaths are due to the spread of cancer, not complications from the original tumor.

10 Dec 2024

Lice as Models for Studying Mitochondrial Disorders

A set of genes that in humans would suggest a late-stage degenerative disease like Parkinson’s or Alzheimer’s disease are present in lice throughout their lives.

10 Dec 2024

Tiny RNA Molecule Controls Wing Coloration in Butterflies and Moths

Lepidopterans (butterflies and moths) exhibit a splendid diversity of wing color patterns, and many species display black and white, or dark and bright, wing color pattern variants associated with the presence and absence of melanin.

9 Dec 2024

Brazilian Study Offers Fresh Perspectives on Pancreatic Cancer Genetics

Pancreatic cancer has recently been included in the list of diseases about which Brazil's National Cancer Institute (INCA) periodically publishes statistics.

9 Dec 2024

Discovery of START Domain Reveals Secrets of Plant Development

Within all complex, multicellular living systems such as plants and humans, there exists a set of genetic elements that can be likened to the blueprints, tools, and specialized personnel at a construction site for an expanding development.

6 Dec 2024

New Discovery Reveals Unintended Genetic Damage in CRISPR-Cas9 Therapy

Genome editing with various CRISPR-Cas molecule complexes has progressed rapidly in recent years.

5 Dec 2024

AI Tool for Accelerating Biological Discovery

Brian Hie leads the Laboratory of Evolutionary Design at Stanford, focusing on the intersection of artificial intelligence and biology.

5 Dec 2024

From Yeast to Humans: Decoding the Link Between Nucleolar Size and Aging

Research reveals that nucleolar enlargement in yeast disrupts genomic integrity, linking size to lifespan and offering insights into aging mechanisms.

5 Dec 2024

Study Evaluates Metrics for Tracking Virus Spread Across Host Populations

Evaluating the speed at which viruses spread and transmit across host populations is critical to mitigating disease outbreaks.

4 Dec 2024

Amborella trichopoda sheds light on ZW sex chromosome evolution in angiosperm plants

A recent study characterizes the ZW sex chromosomes in Amborella trichopoda, revealing insights into sex determination and early evolutionary dynamics in plants.

4 Dec 2024

Bacteria Alter Ribosomes to Resist Common Antibiotics

Bacteria modify their ribosomes when exposed to widely used antibiotics, according to research published today in Nature Communications.

2 Dec 2024

Single-Cell Sequencing Sheds Light on Breast Cancer Genetics

Research reveals somatic copy number alterations in breast epithelial cells, linking early genetic changes to cancer development and highlighting BRCA1/2 roles.

29 Nov 2024

Study Links MICOS10 Gene Defect to Mitochondrial DNA Depletion Syndrome

Mitochondrial DNA depletion syndrome (MTDPS) is a rare genetic disorder characterized by a marked decrease in mitochondrial DNA (mtDNA).

27 Nov 2024

Single-Cell Analysis Sheds Light on Leukemia Cell Heterogeneity

Chromosomal instability plays a crucial role in the progression of cancer: it shapes the properties of tumor cells and drives the development of therapy resistance. Scientists from the German Cancer Research Center (DKFZ), the Heidelberg Stem Cell Institute HI-STEM and the European Molecular Biology Laboratory (EMBL) used state-of-the-art single-cell analysis methods to analyze the cellular heterogeneity of a specific form of acute myeloid leukemia.

26 Nov 2024

Uncovering the Genetic Basis of Sex Determination in Amborella trichopoda

Although it is a complicated process, plant reproduction is essential to both ecological balance and the food chain. Some plants are hermaphrodites, some are either male or female, and some change sex during their lives.

26 Nov 2024

Researchers Decode Complete Genome of Medicinal Plant Forsythia Suspensa

A recent study has decoded the complete genome of Forsythia suspensa, a plant renowned for its medicinal value and decorative appeal.

23 Nov 2024

Human Cell Atlas Consortium Makes Major Progress in Understanding the Human Body

Researchers with the global Human Cell Atlas (HCA) consortium report significant progress in their quest for a better understanding of the cells of the human body in health and disease, with the publication today (20 November) of a Collection of more than 40 peer-reviewed papers in Nature and other Nature Portfolio journals.

22 Nov 2024

Chromosome Abnormalities Found in Healthy Women’s Breast Cells

A new study from researchers at The University of Texas MD Anderson Cancer Center finds that, in healthy women, some breast cells that otherwise appear normal may contain chromosome abnormalities typically associated with invasive breast cancer. The findings question conventional thinking on the genetic origins of breast cancer, which could influence early cancer detection methods.

22 Nov 2024

Discovery of Large Tandem Duplications Opens New Avenues for Cancer Treatment

Cancer researchers at the University of Chicago and the University of California, San Francisco (UCSF) have discovered that mutations in certain genes can lead to the accumulation of DNA errors, resulting in a specific type of genetic change known as large tandem duplications (TDs) that can arise from the collision of two critical cellular processes: transcription and DNA replication.

21 Nov 2024