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Metabolic Profiling of Lung-Resident NK Cells Reveals Novel Therapeutic Targets

Trinity College Dublin researchers, based at St James's Hospital have provided important insights into the behavior and metabolic function of a previously largely unknown, but crucial 'natural killer' (NK) immune cell resident in the lungs.

14 Oct 2024

New RNA Molecule Found to Boost Wound Healing

A new study from Karolinska Institutet in Sweden and the Chinese Academy of Medical Sciences has identified an RNA molecule that is important for skin wound healing. The research, published in Nature Communications, may have implications for the treatment of hard-to-heal wounds.

9 Oct 2024

Human Stem Cell-Derived Retinal Organoid Sheets Close Macular Holes

Researchers reported in the journal Stem Cell Reports that retinal holes in a monkey model were successfully healed by transplanting human stem cells. Following transplantation, retinal tissue was continuously added to the macular holes to seal them.

4 Oct 2024

EPA-Funds Study on Antimicrobial Resistance in Wastewater and Agricultural Runoff

Aided by a $2.4 million grant from the Environmental Protection Agency, a team of University of Nebraska–Lincoln engineers and scientists is leading a multi-state effort to assess the potential threat to human health from antimicrobial-resistant pathogens spread via wastewater and agricultural runoff.

4 Oct 2024

Structural Discovery of Fanzor Proteins Offers New Directions in Genome Engineering

A revolution in biomedicine is currently underway, driven by the application of genome engineering tools such as the prokaryotic CRISPR-Cas9.

3 Oct 2024

Study Confirms Comparable Efficacy of Lamotrigine and Mexiletine in Muscle Channelopathy

The study, published in Lancet Neurology, detailed the "head-to-head" trial implemented by the researchers to test two drugs, mexiletine and lamotrigine, on people with the condition.

30 Sep 2024

The Role of Macrophages in Shaping the Inflammatory Environment in Rheumatoid Arthritis

Currently there are no cures for rheumatoid arthritis (RA) which affects 40,000 people in Ireland. The disease costs an estimated €20,000 per patient, per year with an overall cost to the health system of ~€544 million. Only 1 in 4 patients achieve remission and a significant proportion of patients have suboptimal responses or no response at all to current available therapies.

30 Sep 2024

29 Novel Antibodies Targeting Drug-Resistant Klebsiella Pneumoniae Identified

Research at UMC Utrecht has identified 29 novel antibodies against the bacterium Klebsiella pneumoniae, an important cause of drug-resistant infections.

27 Sep 2024

Harnessing the Power of Beneficial Bacteria to Fight Enterobacteriaceae

Antibiotic-resistant bacterial infections often occur in patients with chronic inflammatory intestinal conditions, such as inflammatory bowel disease, and in patients who have taken antibiotics for a long time. Gram-negative bacteria such as Enterobacteriaceae are a common cause of these infections and have few treatment options. Fecal microbiota transplants have shown promise to curb some of these infections, but their composition varies between batches and they aren't always successful.

23 Sep 2024

Novel Tool Helps Identify Snake Venom Genes Across Species

Only about ten percent of the world's roughly 4,000 snake species have venom strong enough to seriously hurt a human, but that's enough for snake bites to be an important public health concern.

20 Sep 2024

Sodium Transport Found to Play a Surprising Role in Mitochondrial Energy Production

The GENOXPHOS (Functional Genetics of the Oxidative Phosphorylation System) group at the Centro Nacional de Investigaciones Cardiovasculares (CNIC) has discovered a crucial role of sodium in the generation of cellular energy.

20 Sep 2024

New study highlights the medicinal potential of plants consumed by gorillas

In a recent study, researchers examined the antibacterial and antioxidant properties of plants used by western lowland gorillas for self-medication, highlighting the potential of these bioactive compounds for therapeutic applications in human medicine.

19 Sep 2024

IgM Antibodies Offer Protection Against Staph Infections

One of the main sources of community- and hospital-acquired infections is Staphylococcus aureus, well known for its antibiotic-resistant variation Methicillin-resistant Staphylococcus aureus (MRSA)

18 Sep 2024

Innovative Approach Supercharges T Cells by Transferring Healthy Mitochondria

Fighting cancer is exhausting for T cells. Hostile tumor microenvironments can drain their mitochondrial activity, leading to a condition known as T cell exhaustion.

16 Sep 2024

Study Reveals How Surface Properties Affect Bacterial Motility

As bacteria continue to become more resistant to antibiotics, it will be harder to treat bacterial infections, leading to more severe illnesses, longer hospital stays, and higher mortality rates.

10 Sep 2024

Study Reveals Cytoskeleton as Key Component in Aging Dermal Fibroblasts

A new research paper was published on the cover of Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, Issue 16 on August 27, 2024, entitled, "Proteomic and secretomic comparison of young and aged dermal fibroblasts highlights cytoskeleton as a key component during aging."

4 Sep 2024

Hospital News and Research

Metabolic Profiling of Lung-Resident NK Cells Reveals Novel Therapeutic Targets

New RNA Molecule Found to Boost Wound Healing

Human Stem Cell-Derived Retinal Organoid Sheets Close Macular Holes

EPA-Funds Study on Antimicrobial Resistance in Wastewater and Agricultural Runoff

Structural Discovery of Fanzor Proteins Offers New Directions in Genome Engineering

Study Confirms Comparable Efficacy of Lamotrigine and Mexiletine in Muscle Channelopathy

The Role of Macrophages in Shaping the Inflammatory Environment in Rheumatoid Arthritis

29 Novel Antibodies Targeting Drug-Resistant Klebsiella Pneumoniae Identified

Harnessing the Power of Beneficial Bacteria to Fight Enterobacteriaceae

Novel Tool Helps Identify Snake Venom Genes Across Species

Sodium Transport Found to Play a Surprising Role in Mitochondrial Energy Production

New study highlights the medicinal potential of plants consumed by gorillas

IgM Antibodies Offer Protection Against Staph Infections

Innovative Approach Supercharges T Cells by Transferring Healthy Mitochondria

Study Reveals How Surface Properties Affect Bacterial Motility

Study Reveals Cytoskeleton as Key Component in Aging Dermal Fibroblasts

Genetic Variants Linked to Rare Bicuspid Aortic Valve Disease Identified

Melbourne Researchers Achieve Breakthrough in Creating Human-Like Blood Stem Cells

Pan-Pathogen Deep Sequencing: A New Strategy in Combating Nosocomial Antimicrobial Resistant Bacterial Infections

New Study Reveals Antibiotic Mismanagement in Aged Care Facilities

Driving Support for Pharmaceutical Testing Through Continuous Innovation

From Memory to Metaplasticity: Unraveling the Brain's Secrets

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

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