Mammalian Cells News and Research

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Researchers identify evolutionarily conserved pathway responsible for "closing down" gene activity

University of North Carolina Lineberger Comprehensive Cancer Center researchers have identified a new and evolutionarily conserved pathway responsible for "closing down" gene activity in the mammalian cell.

3 Nov 2020

New DNA-cutting tool could advance gene editing for novel treatments

Gene editing for the development of new treatments, and for studying disease as well as normal function in humans and other organisms, may advance more quickly with a new tool for cutting larger pieces of DNA out of a cell's genome, according to a new study by UC San Francisco scientists.

21 Oct 2020

80-year-old antibiotic redesigned for new medical uses

Physicians and scientists have long searched the natural world for chemicals that can improve human health.

5 Oct 2020

Study explains the organization of genetic information contained within mitochondria

Mitochondria creates energy for cells, and are called the “powerhouse". The genetic information is present within the mitochondria for making this energy.

30 Sep 2020

Largely ignored 'housekeeping' gene plays unexpected role in neurological diseases

Within cells, molecules known as transfer RNAs, or "tRNAs," play an important but unglamorous workhorse role in keeping the genetic translation process moving along from codes of DNA to functional proteins.

27 Aug 2020

New device can help grow human gut bacteria that protect against inflammation

Several thousand strains of bacteria live in the human gut. Some of these are associated with disease, while others have beneficial effects on human health.

From Massachusetts Institute of Technology (MIT) 7 Aug 2020

Heparin blocks SARS-CoV-2 infection in cell studies

In a test of antiviral effectiveness against the virus that causes COVID-19, an extract from edible seaweeds substantially outperformed remdesivir, the current standard antiviral used to combat the disease.

27 Jul 2020

Study: PINK1 and Parkin work together to induce selective autophagy

Researchers at TMIMS have revealed that PINK1 (a serine/threonine kinase) and Parkin (a ubiquitin ligating enzyme: E3) work together to ubiquitylate the outer membrane proteins of damaged mitochondria to induce selective autophagy called mitophagy.

10 Jul 2020

Scientists develop CRISPR-assisted method to detect RNA-binding proteins in living cells

While scientists still don't fully understand the diverse nature of RNA molecules, it is believed that the proteins binding to them, called RNA-binding proteins, are associated with many disease formation.

2 Jul 2020

Manipulating immune cells could be a viable strategy for treating cancer

Most traditional cancer therapies target either the tumor cells themselves or indiscriminately kill any rapidly dividing cell.

From UC San Diego 23 Jun 2020

Engineered human cells mimic transparent abilities of squids

Sea creatures can perform a disappearing act by employing unique tissues in their bodies to exploit the reflection and transmission of light.

9 Jun 2020

Human protein plays crucial role in transcription and genome integrity

Researchers from the University of Seville and Cabimer discover that the UAP56/DDX39B protein remove DNA-RNA hybrids from the genome.

5 Jun 2020

‘Terminator’ protein halts tumorigenesis

Essential processes in mammalian cells are controlled by proteins called transcription factors. For example, the transcription factor HIF-1 is triggered by a low-oxygen situation to cause the cell to adapt to decreased oxygen.

4 Jun 2020

New CRISPR-Cas9 based method for directed protein evolution

"Directed evolution" is the process by which scientists produce tailor-made proteins for cell biology, physiology and biomedicine in the laboratory.

28 May 2020

Nanodevices give unprecedented peek into how cells change with time

For the first time, scientists have introduced minuscule tracking devices directly into the interior of mammalian cells, giving an unprecedented peek into the processes that govern the beginning of development.

From University of Bath 27 May 2020

New study on proteins advances basic understanding of human life

A minute chemical modification on one of the most copious and vital proteins in cells—actin—has been a mystery as its function is not fully known.

9 Apr 2020

New microscopy technique reveals movements of cell muscles in unprecedented detail

For the first time, researchers from the University of Warwick have observed the movements of cell muscles in the form of minute filaments of proteins at unparalleled detail.

From The University of Warwick 8 Apr 2020

Genetically manipulating cells using synthetic materials to construct artificial structures

Researchers at the Stanford School of Engineering have designed a technique for reprogramming cells to use synthetic materials, which the team provides, to create artificial structures that can perform functions within the body.

20 Mar 2020

New CRISPR technology targets thousands of genes

Thanks to CRISPR-based genetic screens, researchers were able to detect genes that play a major role in lung cancer metastasis, cancer immunotherapy, sickle-cell anemia, and a host of other medical disorders.

18 Mar 2020

New correlative, 3D, super resolution imaging platform reveals unexpected findings in mammalian cells

Researchers have developed a platform for the 3D super-resolution imaging at the nanoscale level that has revealed unexpected findings in mammalian cells.

21 Feb 2020