Metabolite News and Research

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Metabolites are the intermediates and products of metabolism. The term ''metabolite'' is usually restricted to small molecules.

Metabolite produced by gut microbes found to be involved in regulating commensal bacteria

Researchers at the RIKEN Center for Integrative Medical Sciences (IMS) have discovered that acetate, a major metabolite produced by some intestinal bacteria, is involved in regulating other intestinal bacteria.

20 Jul 2021

Gene therapy may be safe and effective in treating AADC deficiency

A new study published in Nature Communications suggests that gene therapy delivered into the brain may be safe and effective in treating aromatic L-amino acid decarboxylase (AADC) deficiency.

19 Jul 2021

Isoflavone diet plus metabolizing gut bacteria may provide protection against MS

A new University of Iowa study suggests that metabolism of plant-based dietary substances by specific gut bacteria, which are lacking in patients with multiple sclerosis (MS), may provide protection against the disease.

14 Jul 2021

Study reveals the relationship between gut microbiome and neurodegenerative disorders

Eran Blacher bagged the NOSTER & Science Microbiome Prize 2021 for his work in highlighting the relationship between the microbiome and neurodegenerative diseases.

12 Jul 2021

New method for generating metabolic profiles of individual cells

Researchers from the EMBL and the German Cancer Research Center (DKFZ) demonstrated a new technique to create metabolic profiles of individual cells.

8 Jul 2021

Plants evolve defensive systems through a combination of environmental factors

According to research plants acquire unique defensive compounds through the collective effects of genes, geography, and environmental circumstances.

17 Jun 2021

Study reveals new insights into role of polyphenols in the soil microbiome

Fruits, vegetables, red wine and chocolate are all rich in polyphenols, natural plant compounds that double as cancer-fighting antioxidants. We can access these foods' health benefits because the microbes in our guts happily feast on them, breaking them down into smaller chemical components.

10 Jun 2021

Single fingerprint can help determine whether someone has touched or ingested class A drugs

A research team explains how they were able to distinguish between the fingerprints of those who handled cocaine with those who have taken the medicine.

From University of Surrey 20 May 2021

Natural molecule can effectively block the binding of human antibodies to SARS-CoV-2

Researchers have found that a natural molecule can effectively block the binding of a subset of human antibodies to SARS-CoV-2. The discovery may help explain why some COVID-19 patients can become severely ill despite having high levels of antibodies against the virus.

23 Apr 2021

Microfluidic probe sends free radicals on live cells

Is there a way to chemically manipulate small, confined areas on cellular surfaces? Scientists have developed a microfluidic probe to send a flow of free radicals on live cells and track the outcome using fluorescence imaging.

7 Apr 2021

Novel, non-invasive biomarker test could help measure, track performance of senolytics

Scientists from Buck Institute have identified and are now developing an innovative, non-invasive biomarker test that could help quantify and track the performance of senolytics—a class of drugs that selectively destroy senescent cells.

5 Apr 2021

Supercomputer simulations help uncover the mechanism for HIV replication

Viruses lurk in the grey area between the living and the nonliving, according to scientists. Like living things, they replicate but they don't do it on their own. The HIV-1 virus, like all viruses, needs to hijack a host cell through infection in order to make copies of itself.

1 Apr 2021

New automated workflow to identify genetic basis of microbial growth inhibition

Researchers at the Earlham Institute (EI) have created a new automated workflow using liquid handling robots to identify the genetic basis to prevent plant pathogens, which can be used on a much larger and rapid scale than current methods.

5 Mar 2021

Researchers use science to take the guesswork out of cheese manufacturing

Making cheese leaves a lot to chance as a batch could be ripened for months or even years before a problem is discovered, which could send a prized batch of cheddar to be sold off cheap as an ingredient for processed cheese.

2 Mar 2021

Study reveals distinct gut microbiome signature associated with healthy aging, longevity

The gut microbiome is considered an essential part of the body, but its significance in the human aging process is still vague.

22 Feb 2021

New gel electrophoresis method allows rapid diagnosis of biomarkers by mass spectrometry

Polyacrylamide gel electrophoresis is a technique that allows high-resolution isolation of proteins separated from biological specimens.

22 Feb 2021

Study: Phase separated droplets have many important functions in cells

Autophagy is a fundamental cellular process by which cells capture and degrade their own dysfunctional or superfluous components for degradation and recycling.

22 Jan 2021

Fecal microbiome differs in healthy and food-allergic twins

A new study out of the University of Chicago and Stanford University on pairs of twins with and without food allergies has identified potential microbial players in this condition. The results were published on Jan. 19 in the Journal of Clinical Investigation.

20 Jan 2021

Study identifies gene networks that control sugar and organic acid metabolism during fruit development

The watermelon and melon cultivation project by researchers achieved a new advancement in controlling the metabolism of sugar in watermelon fruit.

15 Jan 2021

Pillar-like molecules could be used as biosensors to detect metabolites

Metabolites are essentially organic molecules that are formed or participate during the biochemical reactions that continuously occur in an organism.

12 Jan 2021