Metabolite News and Research

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Metabolites are the intermediates and products of metabolism. The term ''metabolite'' is usually restricted to small molecules.

Blood metabolite levels altered by coffee consumption and may affect chronic kidney disease risk

Food and beverages may have important effects on kidney health, but the potential biological mechanisms involved are often unclear.

5 Nov 2021

Diet-associated molecules in the gut are linked with aggressive prostate cancer

Cleveland Clinic researchers have shown for the first time that diet-associated molecules in the gut are associated with aggressive prostate cancer, suggesting dietary interventions may help reduce risk. Findings from the study were published in Cancer Epidemiology, Biomarkers & Prevention.

29 Oct 2021

Novel process for accurate data analysis from NMR spectrometers

Researchers created a process employing machine learning to enhance data examination from a robust scientific tool—nuclear magnetic resonance (NMR).

23 Sep 2021

Researchers discover underlying metabolic changes that may be pivotal in severe COVID-19

COVID-19 patients have differing immune responses that lead to disease outcomes ranging from asymptomatic SARS-CoV-2 infection to death.

7 Sep 2021

Scientists develop data analysis platform to enhance apple breeding process

A new platform housing data from over 100 apple varieties could shave years off of the breeding process and enable data-driven assessments of how to boost the health benefits of America's favorite fruit.

3 Sep 2021

Novel technique to profile metabolic features using a single isogenic cell sample

A new inexpensive and high-throughput technique for profiling metabolic features using only one isogenic sample of cells has been devised by researchers.

2 Sep 2021

Research reveals link between high-fat diet, gut microbiota and cardiovascular disease

A high-fat diet disrupts the biology of the gut's inner lining and its microbial communities -; and promotes the production of a metabolite that may contribute to heart disease, according to a study published Aug. 13 in the journal Science.

From Vanderbilt University 13 Aug 2021

Study shows plants reuse secondary metabolites in primary metabolism

Plant researchers identified that plants are capable of reusing specialized metabolic products and break them down to recover nutrients.

12 Aug 2021

Metabolite produced by gut microbes found to be involved in regulating commensal bacteria

Researchers at the RIKEN Center for Integrative Medical Sciences (IMS) have discovered that acetate, a major metabolite produced by some intestinal bacteria, is involved in regulating other intestinal bacteria.

20 Jul 2021

Gene therapy may be safe and effective in treating AADC deficiency

A new study published in Nature Communications suggests that gene therapy delivered into the brain may be safe and effective in treating aromatic L-amino acid decarboxylase (AADC) deficiency.

19 Jul 2021

Isoflavone diet plus metabolizing gut bacteria may provide protection against MS

A new University of Iowa study suggests that metabolism of plant-based dietary substances by specific gut bacteria, which are lacking in patients with multiple sclerosis (MS), may provide protection against the disease.

14 Jul 2021

Study reveals the relationship between gut microbiome and neurodegenerative disorders

Eran Blacher bagged the NOSTER & Science Microbiome Prize 2021 for his work in highlighting the relationship between the microbiome and neurodegenerative diseases.

12 Jul 2021

New method for generating metabolic profiles of individual cells

Researchers from the EMBL and the German Cancer Research Center (DKFZ) demonstrated a new technique to create metabolic profiles of individual cells.

8 Jul 2021

Plants evolve defensive systems through a combination of environmental factors

According to research plants acquire unique defensive compounds through the collective effects of genes, geography, and environmental circumstances.

17 Jun 2021

Study reveals new insights into role of polyphenols in the soil microbiome

Fruits, vegetables, red wine and chocolate are all rich in polyphenols, natural plant compounds that double as cancer-fighting antioxidants. We can access these foods' health benefits because the microbes in our guts happily feast on them, breaking them down into smaller chemical components.

10 Jun 2021

Single fingerprint can help determine whether someone has touched or ingested class A drugs

A research team explains how they were able to distinguish between the fingerprints of those who handled cocaine with those who have taken the medicine.

From University of Surrey 20 May 2021

Natural molecule can effectively block the binding of human antibodies to SARS-CoV-2

Researchers have found that a natural molecule can effectively block the binding of a subset of human antibodies to SARS-CoV-2. The discovery may help explain why some COVID-19 patients can become severely ill despite having high levels of antibodies against the virus.

23 Apr 2021

Microfluidic probe sends free radicals on live cells

Is there a way to chemically manipulate small, confined areas on cellular surfaces? Scientists have developed a microfluidic probe to send a flow of free radicals on live cells and track the outcome using fluorescence imaging.

7 Apr 2021

Novel, non-invasive biomarker test could help measure, track performance of senolytics

Scientists from Buck Institute have identified and are now developing an innovative, non-invasive biomarker test that could help quantify and track the performance of senolytics—a class of drugs that selectively destroy senescent cells.

5 Apr 2021

Supercomputer simulations help uncover the mechanism for HIV replication

Viruses lurk in the grey area between the living and the nonliving, according to scientists. Like living things, they replicate but they don't do it on their own. The HIV-1 virus, like all viruses, needs to hijack a host cell through infection in order to make copies of itself.

1 Apr 2021