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AI tools forecast DNA’s regulatory region and 3D structure

According to two recent research published in Nature Genetics, recently created artificial intelligence (AI) tools effectively identified the function of DNA’s regulatory regions and three-dimensional (3D) structure based only on its raw sequence.

9 Aug 2022

Study discovers a molecular mechanism that confers special physical properties to chromosomes in dividing human cells

The Gerlich Group at the Institute of Molecular Biotechnology of the Austrian Academy of Sciences (IMBA) has identified a molecular process that gives chromosomes in dividing human cells unique physical characteristics that permit faithful transmission to the progeny.

8 Aug 2022

Scientists solve how RNA molecules reach their targets

Scientists claim that life does not come with an instruction manual, but this is not totally accurate. Each cell in our body follows the instructions provided by its DNA in the form of RNA molecules.

1 Aug 2022

A Retro-Cascorder device records a cell’s genetic activity in DNA for days at a time

If you want to keep track of someone’s activities for a day, contact them every 10 minutes and inquire what they are up to. It would be simpler, though, to equip them with a journal in which to record their own acts.

1 Aug 2022

Researchers propose a solution to delayed molecular diagnosis and therapy in childhood genetic diseases

Rady Children’s Institute for Genomic Medicine (RCIGM®) recently announced the publication in Nature Communications of research that describes and examines the efficiency of Genome-to-Treatment (GTRxTM), a computer-controlled, virtual disease management system that combines a quick Whole Genome Sequencing (rWGS®) diagnosis accomplished in 13.5 hours with a custom lab management information system and analysis pipeline.

28 Jul 2022

Scientists determine the contribution of DNA recombinations to genomic diversity in health and disease

Researchers from Japan’s RIKEN Center for Integrative Medical Sciences, working with colleagues from all over the world, found that recombinations of particular genomic sequences, which are reproduced millions of times in the genome of each human cell, are common in both normal and disease states.

28 Jul 2022

New method can easily convert commercially available DNA chips into RNA chips

Biochips (microarrays) are modern analytical tools that allow thousands of individual detections to be performed simultaneously in a small amount of sample material. A team led by Mark Somoza from the Faculty of Chemistry at the University of Vienna has now presented a new method in "Nature Communications".

27 Jul 2022

Study highlights the history of ancient DNA technology development

Ancient DNA (aDNA) technology has been used for the past ten years by researchers working under the direction of FU Qiaomei at the Institute of Vertebrate Paleontology and Paleoanthropology (IVPP) of the Chinese Academy of Sciences (CAS) to learn more about the history of ancient human populations, particularly those in East Asia.

26 Jul 2022

Scientists expand entomological research using genome editing

Genome sequencing, in which researchers use laboratory approaches to predict the genetic makeup of a particular organism, is becoming more common in insect studies.

26 Jul 2022

Researchers review the major milestones of ancient DNA techniques

Ancient DNA (aDNA) technology has been used for the past ten years by researchers working under the direction of Qiaomei Fu at the Institute of Vertebrate Paleontology and Paleoanthropology (IVPP) of the Chinese Academy of Sciences (CAS) to learn more about the past of ancient human populations, particularly those in East Asia.

25 Jul 2022

Experts develop new single-cell “chromatin atlas” of the human genome

Researchers from the University of Virginia School of Medicine have developed a crucial new tool that provides a better understanding of how genes in particular cells affect the risk of developing heart disease, the world’s leading cause of death.

25 Jul 2022

Researchers analyze eight assemblers on viral sequencing data

On actual viral next-generation sequencing data, a recent study compares and evaluates eight de novo genome assembly software tools.

22 Jul 2022

Researchers discover potential ways to comprehend DNA replication

Non-coding DNA, also known as “junk DNA,” has been discovered to be anything but harmless and inactive and may even play a role in the onset of cancer.

22 Jul 2022

Research provides better understanding of the Prussian carp's peculiar, efficient reproductive strategy

The Prussian carp is considered one of the most successful invasive fish species in Europe. Its ability to reproduce asexually gives it a major advantage over competing fish.

20 Jul 2022

Insects retain multiple genes from microbes that help them to survive, a new study reveals

Microbes and plants may have given insects an evolutionary benefit, hundreds of millions of years ago, by transferring genes to them via horizontal gene transfer.

20 Jul 2022

Researchers utilize Alismatales to explore plant adaptation to aquatic environments

It is widely believed that life originated in the ocean. Contrarily, the general public does not recognize that many aquatic organisms are descended from terrestrial organisms.

15 Jul 2022

Genetic evolution of tropical freshwater fish may reveal new insights for conservation ecologists

The genetic evolution of freshwater fish in Ecuador could unlock new insights for conservation ecologists. A new collaboration between biologists and computer scientists at DePaul seeks to sequence the genomes of these species.

15 Jul 2022

Octoploids help switchgrass to thrive in new environments

Roughly half of all flowering plants are "polyploid," meaning that they have more than two sets of chromosomes, which contain the plants' genes and DNA.

12 Jul 2022

Using AI to reliably predict the structure of certain RNA molecules

For the function of many biomolecules, their three-dimensional structure is crucial. Researchers are therefore not only interested in the sequence of the individual building blocks of biomolecules, but also in their spatial structure.

11 Jul 2022

Rochester biologists show a selfish “supergene” using population genomics

There are several “selfish genetic elements” in the human genome that do not appear to benefit their hosts but instead appear to exist only to reproduce themselves.

8 Jul 2022