Immune System News and Research

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Single-dose universal vaccine could protect against many types of leptospirosis bacteria

Scientists have designed a single-dose universal vaccine that could protect against the many forms of leptospirosis bacteria, according to a study published today in eLife.

27 Jan 2021

TBI: Increased levels of immune cells promote inflammation that may worsen brain damage

Immediately after a traumatic brain injury and as long as one year later, there are increased levels of immune cells called ILCs in the brain promoting inflammation, which can worsen brain damage, scientists report.

27 Jan 2021

Non-steroidal anti-inflammatory drugs reduce antibody and inflammatory responses to COVID-19

According to a new study, non-steroidal anti-inflammatory drugs (NSAIDs) decreased both inflammatory and antibody responses to SARS-CoV-2 infection in mice.

26 Jan 2021

Study shows major differences in mild versus severe COVID-19 infection

These days, a crucial question on people’s minds is how long does SARS-CoV-2 immunity last after infection?

22 Jan 2021

New CAR T therapy could be more effective and less toxic against neuroblastoma

CAR T therapy has transformed the treatment for leukemia. Regrettably, the therapy is not effective enough to treat solid tumors, like neuroblastoma.

22 Jan 2021

Immunity of COVID-19 patients may rely on antibodies from previous coronavirus infections

The results of a study led by Northern Arizona University and the Translational Genomics Research Institute (TGen), an affiliate of City of Hope, suggest the immune systems of people infected with COVID-19 may rely on antibodies created during infections from earlier coronaviruses to help fight the disease.

22 Jan 2021

Immature dendritic cells in young children can induce robust immune responses

A new study performed by scientists from Ludwig-Maximilians-Universitaet Muenchen (LMU) has demonstrated that putatively immature dendritic cells in young children can trigger powerful immune responses. The findings may result in better vaccination protocols.

21 Jan 2021

Investigational antisense medicine lowers disease burden, reduces myeloma cell abundance in mice

Many patients with multiple myeloma, a type of blood cancer, eventually develop resistance to one treatment after another. That's in part because cancer stem cells drive the disease -- cells that continually self-renew. If a therapy can't completely destroy these malignant stem cells, the cancer is likely to keep coming back.

From UC San Diego 21 Jan 2021

COVID-19 virus triggers antibody response from prior coronavirus infections

According to the results of a study, the immune systems of COVID-19 patients may depend on antibodies that were produced during infections from previous coronaviruses to help combat the disease.

20 Jan 2021

Viral relatives of SARS-CoV-2 can evolve to evade the human immune system

Scientists have shown that two species of seasonal human coronavirus related to SARS-CoV-2 can evolve in certain proteins to escape recognition by the immune system, according to a study published today in eLife.

20 Jan 2021

Exaggerated activation of food quality control system may explain the rising food allergies

For more than three decades, food allergies have been rising drastically across the developed world.

15 Jan 2021

Researchers develop more effective personalized immunotherapy for cancer patients

New research from CU Cancer Center member Jing Hong Wang, MD, PhD, and recent University of Colorado Immunology program graduate Rachel Woolaver, PhD, may help researchers develop more effective personalized immunotherapy for cancer patients.

15 Jan 2021

Targeting RNA splicing can trigger antiviral immune pathways in triple-negative breast cancers

Researchers at Baylor College of Medicine have discovered how therapeutics targeting RNA splicing can activate antiviral immune pathways in triple negative breast cancers (TNBC) to trigger tumor cell death and signal the body's immune response.

15 Jan 2021

Scientists use gene-editing technique to considerably increase the production of formicamycin antibiotics

Researchers have leveraged gene-editing advances to obtain a 10 times increase in the development of super-bug targeting formicamycin antibiotics.

13 Jan 2021

Circadian rhythms control killer cells in the immune system

According to an analysis of data humans’ ability to combat diseases may largely depend on day-to-day circadian cycles than previously believed.

13 Jan 2021

Nanobodies can prevent entry of SARS-CoV-2 coronavirus into human cells

Researchers at Karolinska Institutet in Sweden have developed, in collaboration with researchers in Germany and the U.S., new small antibodies, also known as nanobodies, which prevent the SARS-CoV-2 coronavirus from entering human cells.

13 Jan 2021

Researchers develop novel nanobodies against SARS coronavirus-2

An international research team led by the University of Bonn has identified and further developed novel antibody fragments against the SARS coronavirus-2. These "nanobodies" are much smaller than the classic antibodies used to treat US President Donald Trump, for example.

13 Jan 2021

Immune System News and Research

Single-dose universal vaccine could protect against many types of leptospirosis bacteria

TBI: Increased levels of immune cells promote inflammation that may worsen brain damage

Non-steroidal anti-inflammatory drugs reduce antibody and inflammatory responses to COVID-19

Study shows major differences in mild versus severe COVID-19 infection

New CAR T therapy could be more effective and less toxic against neuroblastoma

Immunity of COVID-19 patients may rely on antibodies from previous coronavirus infections

Immature dendritic cells in young children can induce robust immune responses

Investigational antisense medicine lowers disease burden, reduces myeloma cell abundance in mice

COVID-19 virus triggers antibody response from prior coronavirus infections

Viral relatives of SARS-CoV-2 can evolve to evade the human immune system

Exaggerated activation of food quality control system may explain the rising food allergies

Researchers develop more effective personalized immunotherapy for cancer patients

Targeting RNA splicing can trigger antiviral immune pathways in triple-negative breast cancers

Scientists use gene-editing technique to considerably increase the production of formicamycin antibiotics

Circadian rhythms control killer cells in the immune system

Nanobodies can prevent entry of SARS-CoV-2 coronavirus into human cells

Researchers develop novel nanobodies against SARS coronavirus-2

New model can help identify potential drug targets for ulcerative colitis

Regulatory T cells found to promote inflammation in periodontal disease

Augmented response of immune system explains COVID-19 severity in patients with hypertension

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