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A gene is a unit of heredity in a living organism. It normally resides on a stretch of DNA that codes for a type of protein or for an RNA chain that has a function in the organism. All living things depend on genes, as they specify all proteins and functional RNA chains.

Determining Disease Progression in Patients with Recent-Onset Type 1 Diabetes

A gene expression signature that has the potential to forecast the advance of type 1 diabetes has been determined by scientists from Turku Bioscience Centre and InFLAMES Flagship at the University of Turku in Finland.

30 May 2023

Virally Mediated Gene Therapy Rescues Hearing in Aging Mice

By 2050, one in 10 individuals are expected to live with some form of hearing loss. Of the hundreds of millions of cases of hearing loss affecting individuals worldwide, genetic hearing loss is often the most difficult to treat.

29 May 2023

Combining Proteins With Nano-Based Engineering to Create Circuits

Penn State researchers have developed the first protein-based nano-computing agent that can be used as a circuit.

29 May 2023

How the Disturbed Recycling Chain of Endoplasmic Reticulum Causes Neurodegenerative Diseases

Our cells are crisscrossed by a system of membrane tubes and pockets called the endoplasmic reticulum (ER). It is crucial for the production of biomolecules and is continuously built up and degraded.

29 May 2023

New Insights Into How Genetic Variants Impact Gene Expression

The Department of Biomedical Informatics (DBMI) at the University of Colorado School of Medicine, in collaboration with the University of California San Francisco and Stanford University, has recently published a study that is the largest of its kind to focus on ancestry correlations with biomedical traits.

26 May 2023

Youth Gene "Chinmo" Could Link to Cancerous Processes

Chinmo, the gene responsible for the juvenile stage in insects, has been discovered by researchers. This gene is found in animals and could have a role in cancerous processes.

26 May 2023

Promising Gene Editing Tool Could Tackle Antimicrobial Resistance

A new instrument that has the potential to help minimize the spread of antimicrobial resistance is revealing early potential, by using a bacterial immune system as a gene-editing tool.

26 May 2023

Study Characterizes the Properties of MAIT Cells in Mouse Lung

A population of unconventional white blood cells has recently captured the attention of immunologists and clinicians alike.

26 May 2023

Ex Vivo Expansion of HSCs Using a Novel Culture System

Hematopoietic stem cells (HSCs) are immature blood cells found in the bone marrow that can be stimulated to develop into any type of blood cell.

25 May 2023

Deep-Sequencing Identifies Over 10,000 Unique Genes in Cotton

TEs (transposable elements), particularly LTRs, are recognized to play a crucial role in defining basic genome organization and affecting functional gene expression. Insertion of TE or LTR fragments may also result in the formation of new transcription start sites (TSSs) in the host genome.

25 May 2023

Role of SWI/SNF Chromatin Remodeling Complex in Cell Division

A previously unknown function for the SWI/SNF chromatin remodeling complex has been revealed by researchers at St. Jude Children’s Research Hospital.

25 May 2023

How Epigenetic Landscape Impacts Pioneer Transcription Factor Binding

St. Jude Children’s Research Hospital researchers are investigating how a type of transcription factor known as a pioneer transcription factor reaches DNA even when it is tightly wrapped.

25 May 2023

Identifying Drugs to Put the Brakes On Accelerated Aging From HIV Infection, Treatment

Antiretroviral cocktails can make human immunodeficiency virus, or HIV, undetectable and untransmittable, but both the virus and its treatment can also accelerate aging of bone and muscle.

24 May 2023

Research Uncovers the Biology Underpinning a Rare Genetic Mutation Linked to Painlessness

The biology underpinning a rare genetic mutation that allows its carrier to live virtually pain-free, heal more rapidly and experience reduced anxiety and fear, has been uncovered by new research from UCL.

24 May 2023

Cytoelectric Coupling: Electrical Fields Influence Physical Configuration of Neurons' Sub-Cellular Components

To produce its many functions, including thought, the brain works at many scales. Information such as goals or images is represented by coordinated electrical activity among networks of neurons, while within and around each neuron a mix of proteins and other chemicals physically carries out the mechanics of participating in the network.

23 May 2023

New Insight into the Dynamics of a Ribosomal Protein - RPL3L

A team of researchers have discovered that a mutation in a ribosomal protein found specifically in heart and skeletal muscle leads to impaired cardiac contractility in mice.

23 May 2023

New Method can Help Identify Genome Differences Responsible for Variation in Plant Traits

Plants show enormous variety in traits relevant to breeding, such as plant height, yield and resistance to pests.

23 May 2023

Stimulating Cell DNA Repair Processes to Combat the Root Cause of Autism Spectrum Disorders

A new treatment option has been discovered for fragile X syndrome, which is the most common genetic cause of autism spectrum disorders and is defined by a hereditary repetition of certain nucleotides in the DNA sequence of the FMR1 gene. Researchers at Massachusetts General Hospital (MGH) carried out the study, which was published in the journal Cell.

22 May 2023

From Clocks to Cells: Unleashing the Potential of Dual Oscillatory Signaling

Christian Huygens recorded his observations of the synchronization of two pendulum clocks in 1665. It takes precise quantitative control to properly regulate oscillatory dynamics, which are seen in essential biological processes including circadian clocks, segmentation, and transcription factor responses in addition to physical systems.

22 May 2023

Untangling the Effects of Admixture on the Genomes of Modern Humans

The course of human history has been marked by complex patterns of migration, isolation, and admixture, the latter a term that refers to gene flow between individuals from different populations.

22 May 2023