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Human genome may explain the neonatal origins of immune and inflammatory diseases

A study published in the journal Nature Communications has pinpointed a number of areas of the human genome that may help explain the neonatal origins of chronic immune and inflammatory diseases of later life, including type 1 diabetes, rheumatoid arthritis and coeliac disease.

29 Jul 2020

Study sheds new light on core regulatory networks that govern cell types in vertebrates

The FANTOM Consortium has shed new light into the main regulatory networks that govern the types of cells found in different vertebrate species.

29 Jul 2020

New technology helps visualize entire genome at molecular resolution

Scientists from Harvard University, CNAG, and CRG have demonstrated a pioneering technology that helps observe hundreds of genomes under the microscope.

29 Jul 2020

Testing COVID-19 with FDA-approved drugs can improve outcomes for affected patients

A protein found in viruses that are responsible for causing SARS and COVID-19 infections is virtually identical.

29 Jul 2020

AI algorithm can identify patterns of mutations and prognosis from tumor images

Researchers at EMBL's European Bioinformatics Institute, the Wellcome Sanger Institute, Addenbrooke's Hospital in Cambridge, UK, and collaborators have developed an artificial intelligence algorithm that uses computer vision to analyse tissue samples from cancer patients.

28 Jul 2020

Community-based genetic screening has potential to identify individuals at risk for inherited diseases

In a new study published today in the journal Nature Medicine, researchers behind the Healthy Nevada Project® suggest that community-based genetic screening has the potential to efficiently identify individuals who may be at increased risk for three common inherited genetic conditions known to cause several forms of cancer and increased risk for heart disease or stroke.

28 Jul 2020

EBV viral genome modifies the host epigenetic landscape to promote gastric cancer

The Epstein-Barr virus (EBV), one of the most common human viruses, is associated with about 8-10 per cent of stomach -- or gastric -- cancers, the third leading cause of cancer death globally.

28 Jul 2020

Artificial intelligence-based process can help design novel proteins

Proteins are known to perform complex tasks and catalyze chemical reactions, making them crucial for cell survival.

27 Jul 2020

Computational tool can help study APA mechanism that regulates gene expression

Scientists keen on solving the regulation of genes implicated in human health and disease are widening their horizons by closely APA.

27 Jul 2020

New startup launched to overcome the challenge of delivering next-generation therapeutics

Harvard University's Office of Technology Development (OTD) and the Harvard T.H. Chan School of Public Health today announced the launch of Vesigen Therapeutics, a startup company that aims to overcome the challenge of delivering next-generation therapeutics, such as gene-editing complexes, RNA molecules, and other large proteins, to intracellular targets in specific tissues of interest.

23 Jul 2020

Novel genetic measure could improve screening for osteoporosis

An international team of scientists has developed a novel genetic measure that could dramatically improve how doctors assess the risk of sustaining a fracture due to osteoporosis or fragility.

22 Jul 2020

Researchers comprehensively describe the 'human tissue virome atlas'

Human-resident microbes can influence both health and disease. Investigating the microbiome using next-generation sequencing technology has revealed examples of mutualism and conflict between microbes and humans.

22 Jul 2020

Silver-plated gold nanostars could be used to detect early cancer biomarkers

Biomedical engineers at Duke University have engineered a method for simultaneously detecting the presence of multiple specific microRNAs in RNA extracted from tissue samples without the need for labeling or target amplification.

22 Jul 2020

Researchers use high-quality coral genome to forecast potential bleaching events

In a new approach to conservation genetics, researchers used a high-quality genome of the coral Acropora millepora, along with environmental data, to study this coral's variable responses to climate change, a trait of key conservation importance.

17 Jul 2020

Study shows genetic factors may influence the susceptibility to COVID-19

A new Cleveland Clinic study has identified genetic factors that may influence susceptibility to COVID-19. Published today in BMC Medicine, the study findings could guide personalized treatment for COVID-19.

16 Jul 2020

Genomics study in Black Americans could lead to precision prostate cancer therapies

Black men in the United States are known to suffer disproportionately from prostate cancer, but few studies have investigated whether genetic differences in prostate tumors could have anything to do with these health disparities.

13 Jul 2020

Scientists report detailed proteomic analysis of human lung adenocarcinoma

A team of Chinese scientists from the State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica under the Chinese Academy of Sciences, the State Key Laboratory of Proteomics, National Center for Protein Sciences (Beijing), National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, and Shanghai Jiao Tong University, recently reported a comprehensive proteomic analysis based on 103 Chinese patients with lung adenocarcinoma (LUAD), a leading cause of death among all types of cancer worldwide.

10 Jul 2020

Study explains why human mitochondrial genomes mutate frequently

One could say that mitochondria, the energy-producing organelles inside every human cell, dance to their own beat.

10 Jul 2020

Report highlights role of genomics in perpetuating racism and inequality

Genomics is crowding out ways of reducing inequality, has thwarted medicine from advancing justice, and is creating new forms of social classification and surveillance.

9 Jul 2020

New spatial mapping method pinpoints new potential therapeutic targets for lupus

A team of researchers from Children's Hospital of Philadelphia used a new method of pinpointing potential disease-causing changes in the genome to identify two new potential therapeutic targets for lupus, while also paving the way for more accurately identifying disease-causing variations in other autoimmune disorders.

9 Jul 2020

Genomic News and Research

Human genome may explain the neonatal origins of immune and inflammatory diseases

Study sheds new light on core regulatory networks that govern cell types in vertebrates

New technology helps visualize entire genome at molecular resolution

Testing COVID-19 with FDA-approved drugs can improve outcomes for affected patients

AI algorithm can identify patterns of mutations and prognosis from tumor images

Community-based genetic screening has potential to identify individuals at risk for inherited diseases

EBV viral genome modifies the host epigenetic landscape to promote gastric cancer

Artificial intelligence-based process can help design novel proteins

Computational tool can help study APA mechanism that regulates gene expression

New startup launched to overcome the challenge of delivering next-generation therapeutics

Novel genetic measure could improve screening for osteoporosis

Researchers comprehensively describe the 'human tissue virome atlas'

Silver-plated gold nanostars could be used to detect early cancer biomarkers

Researchers use high-quality coral genome to forecast potential bleaching events

Study shows genetic factors may influence the susceptibility to COVID-19

Genomics study in Black Americans could lead to precision prostate cancer therapies

Scientists report detailed proteomic analysis of human lung adenocarcinoma

Study explains why human mitochondrial genomes mutate frequently

Report highlights role of genomics in perpetuating racism and inequality

New spatial mapping method pinpoints new potential therapeutic targets for lupus

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