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Study discovers new antibiotics effective against drug-resistant tuberculosis

Every year, 1.5 million people die from infections caused by Mycobacterium tuberculosis. Antibiotics are available to treat tuberculosis, but the bacteria has evolved multi-drug resistant (MDR), extensively drug-resistant (XDR), and fully drug-resistant (TDR) strains in recent years.

1 Jun 2022

Study reveals how RNAi workhorse protein optimizes to keep protein synthesis on track

Proteins are made in cells in the same way as they are made in factories. However, making too much at the wrong moment may lead to illnesses like cancer, so they use RNA interference (RNAi) to regulate production.

1 Jun 2022

Researchers conduct a comprehensive survey of the aging epigenome across the chromatin hierarchy

Highly structured chromatin encodes the program of life with only one set of genes in the core of every cell. Since various genes are stimulated at different periods of life while staying silent elsewhere, this is feasible. Some genes from a former life stage are hidden deep within the nuclear perimeter, while others manage to break out.

1 Jun 2022

Researchers analyze the involvement of immune cells in lung cancer survival

Lung cancer affects approximately 48,500 persons in the United Kingdom every year. New treatments are urgently needed because only around 20% of patients live 5 years after diagnosis, and it is the leading cause of cancer death.

1 Jun 2022

Researchers created ultrasound-guided microbubbles to enhance immunotherapy performance

The University of Texas MD Anderson Cancer Center scientists have created an ultrasound-guided cancer immunotherapy approach that promotes systemic antitumor immunity and increases immune checkpoint blockade therapeutic potential. Nature Nanotechnology published the results of the pioneering study.

1 Jun 2022

Scientists discover a new left-handed Z-DNA technique to kill hard-to-treat tumors

An international collaboration of scientists has discovered a new technique to kill cancers that are difficult to treat, according to an article published in Nature.

30 May 2022

Researchers determine the novel medical target of angiogenesis for ccRCC patients

Research reported that the DMDRMR/miR-378a-5p/ DAB2IP axis enhances angiogenesis and sunitinib resistance, suggesting that it could be used for patients with ccRCC.

30 May 2022

Drugs used for myelodysplastic syndrome could potentially activate a sleeping oncogene

Hypomethylating agents (HMA) are currently used as a first-line treatment for patients with myelodysplastic syndrome (MDS) - a group of disorders where there is insufficient production of healthy mature blood cells in the bone marrow - and increasingly in other diseases, but their mechanism of action remains unclear.

From National University of Singapore (NUS) 27 May 2022

Genetic testing advances help to uncover primary immune deficiency diseases

Infections caused by primary immunodeficiency diseases (PID) can be persistent and life-threatening. More than 450 PIDs have been identified, yet diagnosing them quickly and accurately remains a difficulty.

27 May 2022

Easy-to-find soft corals make the elusive "anti-cancer" compound, scientists report

The bottom of the ocean is full of mysteries but scientists have recently uncovered one of its best-kept secrets. For 25 years, drug hunters have been searching for the source of a natural chemical that had shown promise in initial studies for treating cancer.

From The University of Utah 24 May 2022

Researchers devise a new treatment approach to cure aggressive brain tumors

Glioblastomas (GBMs) are cancerous tumors of the brain and spinal cord that are incredibly aggressive.

23 May 2022

Immune-boosting drugs with antibiotics may reduce the health risks of fungal infections

Patients are more susceptible to fungal infections because the immune system in the gut is disrupted when patients are given antibiotics in the hospital.

18 May 2022

Research shows how visible hotspots may be easy to target with immune-stimulating drugs

Many cancers include genetic “hotspots,” or sections of DNA that are subject to mutation. For example, a mutation in the TP53 gene is found in more than 50% of all cancers, generally within a narrow DNA range.

18 May 2022

Scientists detect rare genetic signs of drug-resistant tuberculosis with the aim to stop disease progression

Many people believe tuberculosis (TB) is a disease of the past. Nonetheless, it claims over a million lives each year. Furthermore, the problem is escalating as Mycobacterium tuberculosis—the pathogen that causes tuberculosis develops resistance to the antibiotics used to treat the disease.

12 May 2022

Researchers highlight a phage-antibiotic combo against antibiotic-resistant superbug

A preclinical study performed by Monash University researchers discovered that utilizing a combination of phages and antibiotics to treat bacterial infections may be considerably more successful than using the drugs separately.

12 May 2022

Elective course in biodesign enables students to expand their abilities as medical device innovators

Educators at the Renaissance School of Medicine (RSOM) at Stony Brook University highlighted the success of their three-year, elective course in biodesign that has enabled students to expand their abilities as innovators to creating potential medical devices for the future.

11 May 2022

Clinical News and Research

Study discovers new antibiotics effective against drug-resistant tuberculosis

Study reveals how RNAi workhorse protein optimizes to keep protein synthesis on track

Researchers conduct a comprehensive survey of the aging epigenome across the chromatin hierarchy

Researchers analyze the involvement of immune cells in lung cancer survival

Researchers created ultrasound-guided microbubbles to enhance immunotherapy performance

Scientists discover a new left-handed Z-DNA technique to kill hard-to-treat tumors

Researchers determine the novel medical target of angiogenesis for ccRCC patients

Drugs used for myelodysplastic syndrome could potentially activate a sleeping oncogene

Genetic testing advances help to uncover primary immune deficiency diseases

Easy-to-find soft corals make the elusive "anti-cancer" compound, scientists report

Researchers devise a new treatment approach to cure aggressive brain tumors

Immune-boosting drugs with antibiotics may reduce the health risks of fungal infections

Research shows how visible hotspots may be easy to target with immune-stimulating drugs

Scientists detect rare genetic signs of drug-resistant tuberculosis with the aim to stop disease progression

Researchers highlight a phage-antibiotic combo against antibiotic-resistant superbug

Elective course in biodesign enables students to expand their abilities as medical device innovators

eTesting cannabis for impurities and contaminants

Trial assesses the impact of Mediterranean diet on depression symptoms in young men

bit.bio launches Huntington’s disease human cell model

New technique uses genetic data that may better predict disease risk in a population

Driving Support for Pharmaceutical Testing Through Continuous Innovation

From Memory to Metaplasticity: Unraveling the Brain's Secrets

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

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