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Damaged liver treated in perfusion machine for three days and then implanted into a cancer patient

The multidisciplinary Zurich research team Liver4Life has succeeded in doing something during a treatment attempt that had never been achieved in the history of medicine until now: it treated an originally damaged human liver in a machine for three days outside a body and then implanted the recovered organ into a cancer patient.

1 Jun 2022

Drugs used for myelodysplastic syndrome could potentially activate a sleeping oncogene

Hypomethylating agents (HMA) are currently used as a first-line treatment for patients with myelodysplastic syndrome (MDS) - a group of disorders where there is insufficient production of healthy mature blood cells in the bone marrow - and increasingly in other diseases, but their mechanism of action remains unclear.

From National University of Singapore (NUS) 27 May 2022

Scientists demonstrate how stomach stem cells switch from one state to the other upon injury

A stomach adult stem cell population can fulfill two distinct functions: either help with digestion under normal conditions or take the lead on injury response. S

26 May 2022

Easy-to-find soft corals make the elusive "anti-cancer" compound, scientists report

The bottom of the ocean is full of mysteries but scientists have recently uncovered one of its best-kept secrets. For 25 years, drug hunters have been searching for the source of a natural chemical that had shown promise in initial studies for treating cancer.

From The University of Utah 24 May 2022

Research highlights a novel technique for cancer cells to repair DNA damage

Researchers at the University of Birmingham have identified a novel mechanism for cancer cells to repair DNA damage.

23 May 2022

Rapidly growing nanotechnology firm launches new identity as MIP Discovery

MIP Diagnostics, a leading UK nanotechnology firm has today rebranded to MIP Discovery as the business continues its expansion within the healthcare sector.

From MIP Discovery 19 May 2022

Immune-boosting drugs with antibiotics may reduce the health risks of fungal infections

Patients are more susceptible to fungal infections because the immune system in the gut is disrupted when patients are given antibiotics in the hospital.

18 May 2022

Researchers create open-access atlases of human immune cells in adults

Previously unknown immune cell types throughout development and adulthood have been identified, providing new insights into how the human immune system functions.

18 May 2022

Research shows how visible hotspots may be easy to target with immune-stimulating drugs

Many cancers include genetic “hotspots,” or sections of DNA that are subject to mutation. For example, a mutation in the TP53 gene is found in more than 50% of all cancers, generally within a narrow DNA range.

18 May 2022

Scientist reveals the impact of mitochondria in metastatic prostate cancer

Prostate cancer that has spread to other regions of the body is commonly treated with hormone treatment, but many individuals develop resistance to it, making their disease more aggressive and potentially fatal.

12 May 2022

Scientists detect rare genetic signs of drug-resistant tuberculosis with the aim to stop disease progression

Many people believe tuberculosis (TB) is a disease of the past. Nonetheless, it claims over a million lives each year. Furthermore, the problem is escalating as Mycobacterium tuberculosis—the pathogen that causes tuberculosis develops resistance to the antibiotics used to treat the disease.

12 May 2022

Researchers highlight a phage-antibiotic combo against antibiotic-resistant superbug

A preclinical study performed by Monash University researchers discovered that utilizing a combination of phages and antibiotics to treat bacterial infections may be considerably more successful than using the drugs separately.

12 May 2022

Researchers analyze the effect of dopamine on gene activity and addiction

North Carolina State University researchers have shown that neuron-like cells produced from human stem cells may be used to examine alterations in the neurological system linked to addiction.

10 May 2022

Study reveals advance in cell biology may lead to effective cancer therapy technique

According to researchers at Weill Cornell Medicine and the Dana-Farber Cancer Institute, a protein called CDC7, which has long been assumed to play an important role in cell division, may be replaced by another protein called CDK1.

10 May 2022

Study shows how G protein-coupled receptors signal helps drug development

G protein-coupled receptors (GPCRs), membrane proteins that are the target of one-third of approved drugs, are being studied by scientists at St. Jude Children’s Research Hospital and Columbia University/New York State Psychiatric Institute.

29 Apr 2022

Study shows the role of mucosal-associated invariant T cell in mucosal melanomas patients

Many cancer patients have benefited from the development of anti-cancer immunotherapy drugs known as immune checkpoint inhibitors, but patients with mucosal melanomas—melanomas that occur in the mucous membranes of the head, neck, eyes, respiratory system, and genitourinary region rather than on the skin—are highly resistive to immune checkpoint inhibitors for reasons researchers do not fully understand.

29 Apr 2022

Drugs News and Research

Damaged liver treated in perfusion machine for three days and then implanted into a cancer patient

Drugs used for myelodysplastic syndrome could potentially activate a sleeping oncogene

Scientists demonstrate how stomach stem cells switch from one state to the other upon injury

Easy-to-find soft corals make the elusive "anti-cancer" compound, scientists report

Research highlights a novel technique for cancer cells to repair DNA damage

Rapidly growing nanotechnology firm launches new identity as MIP Discovery

Immune-boosting drugs with antibiotics may reduce the health risks of fungal infections

Researchers create open-access atlases of human immune cells in adults

Research shows how visible hotspots may be easy to target with immune-stimulating drugs

Scientist reveals the impact of mitochondria in metastatic prostate cancer

Scientists detect rare genetic signs of drug-resistant tuberculosis with the aim to stop disease progression

Researchers highlight a phage-antibiotic combo against antibiotic-resistant superbug

Researchers analyze the effect of dopamine on gene activity and addiction

Study reveals advance in cell biology may lead to effective cancer therapy technique

Study shows how G protein-coupled receptors signal helps drug development

Study shows the role of mucosal-associated invariant T cell in mucosal melanomas patients

Scientists determine drug-resistant mold that infects human lungs

Understanding the regulation of intramembrane proteases across the tree of life

CN Bio introduces PhysioMimix NASH ‘in-a-box’ reagent kit

National DNA Day 2022: an interview with Professor Matthew Cobb

Driving Support for Pharmaceutical Testing Through Continuous Innovation

From Memory to Metaplasticity: Unraveling the Brain's Secrets

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

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