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Scientists Unlock the Structure of Vesicular Monoamine Transporter 2

Neurons talk to each other using chemical signals called neurotransmitters. Scientists at St. Jude Children's Research Hospital have drawn on structural biology expertise to determine structures of vesicular monoamine transporter 2 (VMAT2), a key component of neuronal communication.

2 Nov 2023

Exploring the Role of Extracellular Vesicles in Cellular Communication

A research project, jointly conducted by scientists affiliated with the Germans Trias i Pujol Research Institute, has uncovered the potential advantages of employing an agarose spot migration assay for assessing the capacity of extracellular vesicles to attract neighboring cells within a controlled setting.

1 Nov 2023

DNA’s Role in Glioblastoma: Insights from Umeå University’s Research

A groundbreaking research conducted at Umeå University in Sweden has revealed that the three-dimensional arrangement of DNA can impact the development of aggressive brain cancer, glioblastoma.

1 Nov 2023

Novel Activation Mechanism for First Identified Oncogene

In the late 1970s, the link between the c-Src gene and cancer was unveiled, marking the identification of the inaugural oncogene.

1 Nov 2023

Developing 4D High-Resolution Imaging System to Track Cell Movement

Tracking the dynamic movements of cells is crucial for modeling the intricate cellular interactions involved in organ formation, such as the heart.

31 Oct 2023

Targeting eIF4A with Zotatifin: A Promising Strategy for TNBC Treatment

Enhancing treatment options for triple-negative breast cancer (TNBC), a highly aggressive tumor with a grim prognosis and limited therapeutic possibilities has proven to be a formidable challenge.

31 Oct 2023

The Adaptable World of Dendritic Cells in Immunity

Dendritic cells play a pivotal role within the mammalian immune system, being distributed throughout the human body.

31 Oct 2023

New Modular Nanoparticle Technology Opens the Door to a Variety of Therapeutic Approaches

Engineers at the University of California San Diego have developed modular nanoparticles that can be easily customized to target different biological entities such as tumors, viruses or toxins.

31 Oct 2023

The Role of CRISPR-Cas9 in Treating Primary Immunodeficiency Disorders

Severe Combined Immunodeficiencies (SCIDs) encompass a collection of serious primary immunodeficiency disorders primarily instigated by genetic mutations that disrupt the development of T-cells.

30 Oct 2023

Unlocking the Mystery of N-Terminal Acetylation’s Impact on Protein Degradation

Scientists at the University of Bergen (UiB) have discovered that proteins employ a shared chemical marker as a protective shield against degradation, thereby influencing their mobility and the aging process.

30 Oct 2023

Engineered Enzymes Show Promise for Converting Grass Biomass Into Biofuels

Plant biologists at the U.S. Department of Energy's (DOE) Brookhaven National Laboratory have engineered enzymes to modify grass plants so their biomass can be more efficiently converted into biofuels and other bioproducts.

30 Oct 2023

Uncovering New Insights Into Primate Brain Evolution

In a recent research investigation, scientists from Yale University unveiled the molecular pathways responsible for the developmental distinctions that set primates apart from mice.

27 Oct 2023

Exploring the Probiotic Potential of Fungi in Food Production

As detailed in a recent study, two fungi employed in food production exhibit promising probiotic properties that could help alleviate gut inflammation. This research sheds light on a potential avenue for creating novel probiotics.

27 Oct 2023

Novel Replacement Strategy Opens the Door to Therapeutic Interventions for Genomic Diseases

Severe Combined Immunodeficiencies (SCIDs) are a group of debilitating primary immunodeficiency disorders, primarily caused by genetic mutations that disrupt T-cell development.

27 Oct 2023

The Global Biopharma Community is Now Actively Partnering for BIO-Europe® 2023

The 29th annual BIO-Europe, the premier partnering conference for the global biopharmaceutical industry, is set to take place November 6–8, 2023, in the vibrant city of Munich, Germany.

27 Oct 2023

Rab32 and Rab38 Crucial for Bone Resorption and Pigmentation of Skin, Hair

Bone is maintained via delicate balance between formation and resorption, and its imbalance leads to bone related diseases like osteoporosis rheumatism and periodontitis.

26 Oct 2023

ISB Researchers Discover Genetic Key to T Cell Development

T cells are soldiers on the front lines of the human immune system. They are responsible for many important roles, including attacking viral- or bacterial-infected cells and certain cancer cells, and immunological memory – remembering the specific pathogens or the cancer signatures that originally trigger T cells.

26 Oct 2023