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TRPC5 Gene Alterations: A Key Player in Obesity and Postpartum Depression

Researchers at Baylor College of Medicine, the University of Cambridge and collaborating institutions have discovered that alterations in the human gene TRPC5 cause obesity and postpartum depression.

3 Jul 2024

Study Offers Insights Genetic Variants Influencing Pubertal Timing

Genes can indirectly influence the age at which girls have their first period by accelerating weight gain in childhood, a known risk factor for early puberty, a Cambridge-led study has found.

2 Jul 2024

Mice Studies Shed Light on Serotonin and Memory

Memory regulation in humans and animal models is regulated by the serotonin 2C receptor in the brain, according to research from Baylor College of Medicine, the University of Cambridge in the United Kingdom, and affiliated institutions.

1 Jul 2024

Primitive Endoderm Stem Cells Offer New Hope for Fertility Treatments

An unexpectedly versatile and regenerative stem cell in early embryos may be key to creating new effective fertility treatments, suggests a new study in mice from the University of Copenhagen.

25 Jun 2024

St. Jude Researchers Discover NLRC5's Role in Inflammatory Cell Death

The innate immune system is responsible for protecting the human body from threats that could cause disease or infection.

17 Jun 2024

New Clinical Trial Offers Path to Sickle Cell Cure

The most recent results from a clinical trial were given by researchers in an effort to find a cure for sickle cell disease, a painful genetic blood illness that has few available treatments.

17 Jun 2024

New Method Offers Rapid and Accurate Blood Infection Detection

Researchers have shown that a novel method could identify bloodstream infections precisely and swiftly. The study findings were presented at ASM Microbe, the annual meeting of the American Society for Microbiology.

17 Jun 2024

Exploring the Use of Weakened Viruses for Cancer Treatment

Scientists at Northwestern Medicine have found that an attenuated virus can aid in the elimination of cancer in mice. Furthermore, mice given this virus treatment had a higher lifetime tumor-prevention rate.

12 Jun 2024

Whole Genome Sequencing Provides Answers Where Exome Sequencing Falls Short

Genetic mutations in human DNA can prevent proteins that perform important functions in the body from being formed correctly.

11 Jun 2024

Researchers Advance Single-Molecule DNA Sequencing Techniques

In recent years, technologies that allow scientists to investigate a person's DNA at single-molecule resolution have greatly increased the knowledge of the human genome, microbiome, and the genetic basis of disease.

5 Jun 2024

"Cervix-on-a-Chip" Offers Promise for New Bacterial Vaginosis Treatments

Bacterial Vaginosis (BV) has been identified as one of the many unmet needs in women's health and affects more than 25% of reproductive-aged women.

3 Jun 2024

Protein Imbalance Linked to Rare Developmental Disorder

According to a recent study from the University of Lausanne, serious intellectual impairments can result from both an excess or a shortage of a single protein.

31 May 2024

Newly Discovered CD8-fit Cells Could Revolutionize Cancer Treatment

A team of cancer researchers, led by the University of Houston, has discovered a new subset of T cells that may improve the outcome for patients treated with T-cell therapies.

30 May 2024

Revolutionizing Cell Subpopulation Studies: The ConVERGD Approach

As gene sequencing technologies become more powerful, our understanding of cellular diversity has grown in parallel.

29 May 2024

Cryo-EM Reveals Structural Insights Into ADAM17/iRhom2 Complex

Efficient communication between cells is vital for many biological processes, such as recruiting immune cells to combat disease.

24 May 2024

Comprehensive Analysis of Gene-Isoform Variation Unlocks Secrets of Brain Development

A team led by researchers at UCLA and the University of Pennsylvania has produced a first-of-its kind catalog of gene-isoform variation in the developing human brain.

24 May 2024

Machine Learning Program Offers Insights Into Promoter Sequences and Transcription

A team led by researchers at UT Southwestern Medical Center developed deep learning models to identify a simple set of rules that govern the activity of promoters – regions of DNA that initiate the process by which genes produce proteins.

15 May 2024

Unlocking the Secrets of Childhood Cancer Genetics

Scientists have revealed a fresh insight into the genetic pathway of childhood cancer, providing new potential for personalized treatment.

15 May 2024

Harnessing High-Performance Computing to Unravel the Emergence of Novel Viruses

Suddenly they appear and - like the SARS-CoV-2 coronavirus - can trigger major epidemics: Viruses that nobody had on their radar.

14 May 2024

Unraveling the Molecular Landscape of Parietal Cell Development

Common conditions such as indigestion and heartburn as well as peptic ulcers, autoimmune gastritis and stomach and esophageal cancers have one thing in common – they involve disruptions of the normal activity of parietal cells (PCs) in the stomach, the only cells in the body that produce acid.

13 May 2024