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A Newly Discovered Plant Gene that Helps Make Apiin: The Search Ends Here

Apiin, a natural compound found in high amounts in parsley and celery, is thought to have important medicinal properties.

24 Aug 2023

Innovative Method Accelerates Discovery of New Drugs by Harnessing the Power of Ribosomes

A research team led by University of California, Irvine scientists has developed an innovative method for quickly and efficiently creating vast collections of chemical compounds used in drug discovery by harnessing the power of ribosomes, the molecules found in all cells that synthesize proteins and peptides.

24 Aug 2023

Epstein-Barr Virus Epigenome Targeted for Potential Cancer Treatment

Now, scientists at The Wistar Institute have discovered a potential target for gastric cancers associated with Epstein-Barr Virus; study results were published in the journal mBio.

23 Aug 2023

Researchers Show How Different Taste Cells are Affected by Inflammation Using Gene Mapping Tool

A bitter taste in the mouth is often a symptom or side effect of illness, which may be the result of how the body reacts to pathogens.

23 Aug 2023

New Breakthrough in Generative AI Models and AlphaFold Structures for Drug Discovery

Insilico Medicine ("Insilico"), a clinical-stage end-to-end generative artificial intelligence (AI) drug discovery company, has achieved a significant breakthrough in the application of multiple generative AI models and AlphaFold structures for drug discovery.

3 Aug 2023

Researchers Discover New Way to Attack Fungal Infections

Researchers at the RIKEN Center for Sustainable Research Science (CSRS) and the University of Toronto have discovered a new way to attack fungal infections.

1 Aug 2023

Researchers Develop New Photoenzymatic Method to Produce Chiral Amines

Using energy from light to activate natural enzymes can help scientists create new-to-nature enzymatic reactions that support eco-friendly biomanufacturing -; the production of fuels, plastics, and valuable chemicals from plants or other biological systems.

1 Aug 2023

New Insights Into Lactate Transporters and Their Therapeutic Potential

Researchers from the Giulio Superti-Furga Lab at CeMM, the Austrian Academy of Sciences’ Research Center for Molecular Medicine, have developed a new technique for identifying specific inhibitors of a lactate transporter linked to cancer and other diseases.

31 Jul 2023

Researchers Make Breakthrough in Fight Against Familial Hypercholesterolemia

The Mona Lisa, painted by the Italian artist Leonardo da Vinci, is one of the most recognizable paintings in the world.

21 Jul 2023

Novel Drug Compound Reduces Sensory Hypersensitivity in Fragile X Mice

Boosting the activity of inhibitory interneurons in Fragile X mice reduced their hypersensitivity to sensory stimuli, according to a new Neuron study led by UCLA Health researchers.

14 Jul 2023

Heat-Damaged DNA in Food Linked to Possible Genetic Risks

Researchers have newly discovered a surprising and potentially significant reason why eating foods frequently cooked at high temperatures, such as red meat and deep-fried fare, elevates cancer risk. The alleged culprit: DNA within the food that's been damaged by the cooking process.

14 Jun 2023

Artificial Light Has Drastic Impact on Male Glow-Worms' Ability to Find Mates

The bright lights of big cities are wonders of the modern world; intended to help us work, stay safe and enjoy the world around us long after the sun has set.

14 Jun 2023

Role of SWI/SNF Chromatin Remodeling Complex in Cell Division

A previously unknown function for the SWI/SNF chromatin remodeling complex has been revealed by researchers at St. Jude Children’s Research Hospital.

25 May 2023

Compound Found in Magnolia Tree Bark Inhibits SARS-CoV-2 Replication in Several Cell Types

A compound called honokiol, which is found in the bark of multiple species of magnolia tree, inhibits replication of SARS-CoV-2 virus in several types of cells, according to a team of researchers in the Netherlands.

23 May 2023

Large Testing Arena Helps Study How Mosquitoes Find Us Over Long Distances

We know a lot about mosquito preferences up close, but how do mosquitoes find us from up to a hundred meters away? Using an ice-rink-sized outdoor testing arena in Zambia, researchers found that human body odor is critical for mosquito host-seeking behavior over long distances.

22 May 2023

A High-Throughput Assay for Identifying and Validating ECHS1 Enzyme Genetic Variants

The enzyme variations of mitochondrial enoyl-CoA hydratase short-chain 1 (ECHS1) are dysfunctional. In Japan, they are mostly responsible for mitochondrial disease.

19 May 2023

Single-Cell Omics Reveals Cell Types Involved in the Biosynthesis of Plant Natural Products

In a new study published in Nature Chemical Biology, an international team of researchers from the University of Georgia, USA, and the Max Planck Institute for Chemical Ecology in Jena, Germany, presents a promising strategy for elucidating metabolic pathways for plant compounds of medicinal importance.

16 May 2023

Essential Oil From the Leaves of Labrador Tea Plant Has Antimalarial Properties

Much of what is now considered modern medicine originated as folk remedies or traditional, Indigenous practices. These customs are still alive today, and they could help address a variety of conditions.

12 May 2023

Innate Tumor Suppression Mechanism Uncovered

The p53 gene is one of the most important in the human genome: the only role of the p53 protein that this gene encodes is to sense when a tumor is forming and to kill it.

5 May 2023

Genes Responsible for Aging Identified in Nematodes

The USask research team uncovered a pair of genes involved in removing cells of toxins that build in the body and cause aging while working with small nematode worms called C. elegans. The researchers discovered that inactivating genes named CCF-1 and PAL-1 caused nematodes to die 50% faster than usual.

3 May 2023