Genes News and Research

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Genes2Genes Unlocks New Potential for Detecting Gene Expression Changes

Genes2Genes an accurately infer alignments in simulated and real datasets of single-cell trajectories and capture sequential mismatches and matches in individual genes.

4 Oct 2024

Discovering New Drug Targets Through Paralog Hopping

Some proteins in the human body are easy to block with a drug; they have an obvious spot in their structure where a drug can fit, like a key in a lock. But other proteins are more difficult to target, with no clear drug-binding sites.

3 Oct 2024

New Insights into the Epigenetic Hallmarks of Cancer

Cancer mortality has just surpassed cardiovascular disease for the first time ever and one in two men, and one in three women, will be diagnosed with some form of the disease in the US, according to the NIH.

3 Oct 2024

A New Understanding of Chromatin Regulation and its Implications

Human survival is dependent upon an extraordinarily intricate dance that takes place inside every cell and every nucleus. DNA is continually being wrapped and unwrapped by proteins, and even small mistakes might result in cancer.

3 Oct 2024

Xinjiang Cotton Fields Show Lasting Benefits From Mulched Drip Irrigation

Long-term mulched drip irrigation enhances soil health, reduces salinity, and increases cotton yields, showcasing its sustainability in water-scarce areas.

3 Oct 2024

New Insights into U1 Snrnp Functions in Plant Splicing Mechanisms Using Arabidopsis

U1 snRNP interactions in Arabidopsis highlight its dual role in splicing and mRNA regulation, essential for maintaining transcript integrity and growth.

2 Oct 2024

Targeting the TCA Cycle to Reduce Post-TB Mortality

Researchers at Baylor College of Medicine and other institutions have discovered a mechanism that causes the long-term decline in immune response observed after tuberculosis (TB) is successfully treated.

1 Oct 2024

Study Reveals Gene Linked to Cold Resistance in Hibernating Mammals

A gene that limits cellular damage could be the key to surviving prolonged cold exposure.

1 Oct 2024

Bipolar Disorder and Epilepsy Share Genetic Roots

A team of researchers from the Chinese Academy of Sciences has uncovered compelling evidence of a genetic link between bipolar disorder type I (BD-I) and epilepsy, potentially revolutionizing our understanding of these complex neuropsychiatric conditions.

1 Oct 2024

Two Alzheimer’s Genetic Risk Factors Trigger Harmful Inflammation in Females

Weill Cornell Medicine investigators have found that two genetic variants that confer high risk of Alzheimer's disease (AD) together trigger a harmful inflammatory response in the brain's immune cells, particularly in females, in a preclinical model.

1 Oct 2024

Hydrogen Sulfide Plays a Crucial Role in Bacterial Survival

Two crucial biological processes that support the growth of bacteria, particularly pathogenic bacteria like Escherichia coli, are antibiotic resistance and the oxidative stress response.

30 Sep 2024

Motor And Extracellular Matrix Proteins Play A Critical Role In Cleft Palate Formation

The study reveals 44 differentially expressed proteins in cleft palate models, shedding light on molecular mechanisms and potential prenatal diagnostic markers.

30 Sep 2024

Study: Vaping Alters DNA in Ways Similar to Smoking

Young adults who vape show chemical changes in their DNA similar to those found in young adults who smoke -; changes known to be linked to the development of cancer -; according to a new study just published in the American Journal of Respiratory Cell and Molecular Biology.

26 Sep 2024

New AI Tool Revolutionizes Prediction of Rare Genetic Variant Effects

Whether we are predisposed to particular diseases depends to a large extent on the countless variants in our genome.

26 Sep 2024

Metagenomic Study Reveals the Most Ancient Dairy Remains Known to Date

The oldest method of producing food with microorganisms in human history is food fermentation. Cheese production and consumption dates back to 7000 before the present (BP) among Mediterranean populations, and milk fermentation, for instance, dates back to 6000–4000 BC in India.

26 Sep 2024

Bacteria Can Recode Their Genetics With a Single Flip

Envision being a single cartwheel away from altering looks. The brown locks will turn platinum blond with just one flip. That is similar to what occurs in certain prokaryotes, or single-celled creatures like bacteria when they go through a process known as inversions.

26 Sep 2024

Stem Cell Study Reveals Developmental Dance Behind Individual Variation

Researchers at the Johns Hopkins University School of Medicine have conducted a comprehensive analysis of the variations present in human stem cells. This study sheds light on how the unique “developmental dance” at the molecular level within an individual's cells can shape the formation of the brain and the body.

26 Sep 2024