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The Evolutionary Timeline of Diminished Boric Acid and Urea Transportation in Aquaporin 10

Aquaporin (Aqp) 10 water channels in humans allow the free passage of water, glycerol, urea, and boric acid across cells.

27 Dec 2023

SpaceX Returns Vital Life Science Research Sponsored by the ISS National Lab

Dozens of science and technology development payloads returned to Earth from the International Space Station (ISS) on December 22 as SpaceX’s 29th Commercial Resupply Services (CRS) mission, contracted by NASA, successfully concluded.

27 Dec 2023

Study Reveals Tissue-Specific Effects of JAK1 Signaling in Inflammation

Researchers at the Icahn School of Medicine at Mount Sinai have gained a deeper understanding of the nuanced roles of JAK inhibitors, or modulators, in inflammation across various cell types and tissues.

26 Dec 2023

Sticky Secrets Revealed: Epithelial Cells Stick and Signal for Perfect Tissues

Australian researchers have discovered a new way that epithelial cells, which form layers in organs like the skin and stomach, attach to one another, and how they perceive growth signals at these attachments, helping them form tissues of the right size and shape.

22 Dec 2023

Intermittent Energy Restriction Diet Alters Brain-Gut-Microbiome Axis

Worldwide, more than one billion people are obese. Obesity is a risk factor for cardiovascular disease, diabetes, and some cancers.

21 Dec 2023

Unveiling the Role of Exosomes in Regulating Hepatic Lipid Metabolism

Non-alcoholic fatty liver disease (NAFLD), characterized by an excess accumulation of hepatic lipids, is highly prevalent and can progress to cirrhosis and liver cancer.

12 Dec 2023

Unraveling the Complexities of Gene Regulation with MAbID

A novel technique named MAbID, developed by researchers led by Jop Kind, has been introduced to concurrently investigate various mechanisms of gene regulation, crucial for both development and disease processes.

5 Dec 2023

Engineering Stem Cells to Evade Immune Rejection

Cell and organ transplants have the potential to save lives; however, patients frequently face prolonged waiting periods as a result of the insufficient availability of suitable donors.

23 Nov 2023

New Drug-Like Molecule Enhances Mitophagy, Protects Against Neurodegeneration

Having healthy mitochondria, the organelles that produce energy in all our cells, usually portends a long healthy life whether in humans or in C. elegans, a tiny, short-lived nematode worm often used to study the aging process.

14 Nov 2023

Scientists Identify 4,749 Gene Clusters Linked to Cancer Prognosis

Researchers at the Mount Sinai Center for Transformative Disease Modeling have released a groundbreaking study identifying 4,749 key gene clusters, termed "prognostic modules," that significantly influence the progression of 32 different types of cancer.

14 Nov 2023

Seventh Annual NSF-Funded Solicitation for Tissue Engineering Research Utilizing the ISS National Lab Now Open

For the seventh consecutive year, the U.S. National Science Foundation (NSF) is funding a solicitation seeking projects that utilize the International Space Station (ISS) National Laboratory to advance tissue engineering and mechanobiology research. Through this solicitation, NSF will provide up to $1.6 million in funding for multiple projects intending to leverage the orbiting laboratory.

10 Nov 2023

New Technique Unveils the Secrets of Osmotic Pressure in Living Organisms

In order to survive, organisms must control the pressure inside them, from the single-cell level to tissues and organs.

6 Nov 2023

New Study Sheds Light on Evolution of Sex Differences in Animals

Researchers at the Francis Crick Institute and Heidelberg University in Germany have shown that sex differences in animals vary dramatically across species, organs and developmental stages, and evolve quickly at the gene level but slowly at the cell type level.

3 Nov 2023

Prime Editing and Base Editing Could Revolutionize Treatment for Phenylketonuria

Phenylketonuria (PKU) is a rare newborn genetic disease that impacts between 1 in 10,000 to 1 in 20,000 people, depending on the individuals' genetic ancestry. PKU causes an amino acid-;called phenylalanine (Phe)-;to build up in the bloodstream.

3 Nov 2023

Novel Activation Mechanism for First Identified Oncogene

In the late 1970s, the link between the c-Src gene and cancer was unveiled, marking the identification of the inaugural oncogene.

1 Nov 2023

Kingfisher Genes Reveal Secrets of How They Dive Without Sustaining Brain Damage

If you've ever belly-flopped into a pool, then you know: water can be surprisingly hard if you hit it at the wrong angle. But many species of kingfishers dive headfirst into water to catch their fishy prey.

24 Oct 2023

New Way to Visualize Tumors During Surgery

Surgeons often face the challenge of achieving precise tumor removal while preserving healthy tissue. Traditionally, they rely on their visual and tactile senses to determine where to make incisions.

17 Oct 2023

Targeting Microbiota 2023: A Ground-Breaking Experience in Microbiome Research

Targeting Microbiota 2023 will be a ground-breaking experience that will introduce you to the latest advancements in the microbiota field.

6 Oct 2023

Research Offers a Promising Avenue for Improving T-Cell-Based Cancer Therapies

Using laboratory-grown cells from humans and genetically engineered mice, scientists at Johns Hopkins Medicine say they have evidence that modifying a specific protein in immune white blood cells known as CD8+ T cells can make the cells more robust, potentially opening the door for better use of people's own immune system T cells to fight cancer.

4 Oct 2023

Living Model of Human Liver Offers Help in Combating Liver Diseases

Fatty liver disease is on the rise worldwide, affecting up to 30% of people in Western countries. In addition to drinking, obesity and diabetes are major risk factors.

3 Oct 2023