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Circadian Rhythm Disrupts Gut Barrier in Cancer

Research from the University of California, Irvine has revealed how disruption of the circadian clock, the body's internal, 24-hour biological pacemaker, may accelerate the progression of colorectal cancer by affecting the gut microbiome and intestinal barrier function. This discovery offers new avenues for prevention and treatment strategies.

30 Sep 2024

Insights into the Formation of Nascent Membrane Structures in Yeast Sporulation

Sexual reproduction, a common mode of reproduction among numerous species, involves gametogenesis in which offspring are produced through fertilization, conjugation, or mating. In plants and animals, eggs and sperm differentiate from germ cells to form gametes.

30 Sep 2024

Genomic Insights Reveal Path Forward for Inbred Red Fox Populations

A rescue effort can take many forms – a life raft, a firehose, an airlift. For animals whose populations are in decline from inbreeding, genetics itself can be a lifesaver.

27 Sep 2024

Human Cells Exhibit Dormant State Similar to Embryonic Diapause

In some mammals, the timing of the normally continuous embryonic development can be altered to improve the chances of survival for both the embryo and the mother.

27 Sep 2024

Study: Vaping Alters DNA in Ways Similar to Smoking

Young adults who vape show chemical changes in their DNA similar to those found in young adults who smoke -; changes known to be linked to the development of cancer -; according to a new study just published in the American Journal of Respiratory Cell and Molecular Biology.

26 Sep 2024

New AI Tool Revolutionizes Prediction of Rare Genetic Variant Effects

Whether we are predisposed to particular diseases depends to a large extent on the countless variants in our genome.

26 Sep 2024

Research Reveals How the Brain Encodes Time and Experiences at the Neuronal Level

A landmark study led by UCLA Health has begun to unravel one of the fundamental mysteries in neuroscience – how the human brain encodes and makes sense of the flow of time and experiences.

26 Sep 2024

Bacteria Can Recode Their Genetics With a Single Flip

Envision being a single cartwheel away from altering looks. The brown locks will turn platinum blond with just one flip. That is similar to what occurs in certain prokaryotes, or single-celled creatures like bacteria when they go through a process known as inversions.

26 Sep 2024

Stem Cell Study Reveals Developmental Dance Behind Individual Variation

Researchers at the Johns Hopkins University School of Medicine have conducted a comprehensive analysis of the variations present in human stem cells. This study sheds light on how the unique “developmental dance” at the molecular level within an individual's cells can shape the formation of the brain and the body.

26 Sep 2024

The Lasting Effects of COVID-19 on the Brain

In the UK’s largest study to date, novel steps have been taken to gain a better understanding of the immediate and long-term effects of COVID-19 on the brain.

25 Sep 2024

Study Uncovers Cholesterol's Role in Membrane Structure and Function

A new study by Rice University researchers led by Jason Hafner could open new pathways for understanding how cholesterol influences cell membranes and their receptors, paving the way for future research on diseases linked to membrane organization.

24 Sep 2024

Identifying Risk Factors for CAPA in COVID-19 Patients

As society adapts to COVID-19, the study of the illness and its side effects is still crucial. To ascertain the prevalence of COVID-19-associated pulmonary aspergillosis (CAPA), a severe invasive fungal infection of the lungs, in Japan, a team from Osaka Metropolitan University has combed through data.

23 Sep 2024

DNA Duplication Determines Horse Coat Color and Melanoma Risk

Scientists from the Texas A&M College of Veterinary Medicine and Biomedical Sciences (VMBS) and Uppsala University in Sweden now understand why some gray horses turn completely white as they age, while others remain an eye-catching "dappled" gray color.

23 Sep 2024

Harnessing the Power of Beneficial Bacteria to Fight Enterobacteriaceae

Antibiotic-resistant bacterial infections often occur in patients with chronic inflammatory intestinal conditions, such as inflammatory bowel disease, and in patients who have taken antibiotics for a long time. Gram-negative bacteria such as Enterobacteriaceae are a common cause of these infections and have few treatment options. Fecal microbiota transplants have shown promise to curb some of these infections, but their composition varies between batches and they aren't always successful.

23 Sep 2024

Novel Tool Helps Identify Snake Venom Genes Across Species

Only about ten percent of the world's roughly 4,000 snake species have venom strong enough to seriously hurt a human, but that's enough for snake bites to be an important public health concern.

20 Sep 2024

Sodium Transport Found to Play a Surprising Role in Mitochondrial Energy Production

The GENOXPHOS (Functional Genetics of the Oxidative Phosphorylation System) group at the Centro Nacional de Investigaciones Cardiovasculares (CNIC) has discovered a crucial role of sodium in the generation of cellular energy.

20 Sep 2024

Low Extracellular Sodium Concentrations Can Suppress mRNA Expression in Brain Cells

Brain and mental problems can result from chronic hyponatremia, a disorder marked by low blood salt levels.

19 Sep 2024

New study highlights the medicinal potential of plants consumed by gorillas

In a recent study, researchers examined the antibacterial and antioxidant properties of plants used by western lowland gorillas for self-medication, highlighting the potential of these bioactive compounds for therapeutic applications in human medicine.

19 Sep 2024