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Deciphering the Tumor Microenvironment with Spatial Transcriptomics

Spatial transcriptomics (ST) has emerged as a crucial technique for mapping gene expression across tissue sections while preserving vital locational data, setting it apart from traditional methods like bulk or single-cell RNA sequencing.

30 Nov 2023

Unveiling the Cerebellar Nuclei’s Role in Associative Learning

The regulation of associative learning was traditionally believed to be controlled by the cortex within the cerebellum, commonly known as the “little brain.”

21 Nov 2023

Artificial System Develops Key Characteristics Similar to Human Brains Under Physical Constraints

Cambridge scientists have shown that placing physical constraints on an artificially-intelligent system – in much the same way that the human brain has to develop and operate within physical and biological constraints – allows it to develop features of the brains of complex organisms in order to solve tasks.

21 Nov 2023

Study Reveals Crucial Protein’s Role in Brain Cell Development

Scientists from the University of Wisconsin–Madison have pinpointed a crucial protein associated with the formation of a specific type of brain cell implicated in conditions such as Alzheimer’s and Parkinson’s diseases.

20 Nov 2023

More Genes Changed By Early Life Stress Than Head Injury

Researchers recently discovered a phenomenon as they delved into the investigation of whether early-life stress exacerbates the impact of a childhood head injury on health and behavior in later years.

16 Nov 2023

Rare Genetic Variant Found to Protect Against Alzheimer's Disease

Researchers at Gladstone Institutes have discovered that a rare genetic variant known as the "Christchurch mutation" can block detrimental effects of apolipoprotein E4, the best-established risk factor for the most common form of Alzheimer's disease.

14 Nov 2023

Scientists Identify 4,749 Gene Clusters Linked to Cancer Prognosis

Researchers at the Mount Sinai Center for Transformative Disease Modeling have released a groundbreaking study identifying 4,749 key gene clusters, termed "prognostic modules," that significantly influence the progression of 32 different types of cancer.

14 Nov 2023

Exploring How Climate Change Could Impact Our Brain Function in the Future

A new element of the catastrophic impacts of climate change is emerging – how global warming is impacting the human brain.

14 Nov 2023

Role of Inhibitory Interneurons in Memory Expression

Memory, a crucial aspect of human survival, is intricately connected to how humans encode, retrieve, and react to external stimuli.

9 Nov 2023

Unlocking the Secrets of Memory: Key Protein Regulates Hippocampal Plasticity

Mount Sinai researchers have shed valuable light on the mechanism of a key protein that regulates the plasticity and function of the hippocampus, a key brain region involved in memory and learning, and that decreases with age in mice.

3 Nov 2023

Uncovering New Insights Into Primate Brain Evolution

In a recent research investigation, scientists from Yale University unveiled the molecular pathways responsible for the developmental distinctions that set primates apart from mice.

27 Oct 2023

Developing Regenerative Therapies to Treat Neurological Conditions

The primary cells that make up our brain and spinal cord, called neurons, are among the slowest to heal after injury, and many neurons never fully recover. Although research into neural regeneration has advanced, it is still unclear why certain neurons recover while others do not.

17 Oct 2023

New Microscopy Technique Reveals Unprecedented Details of Amyloid Plaques in Alzheimer's Disease

Researchers from the Universitat Autònoma de Barcelona (UAB), the Karolinska Institute (KI), and the biotechnology company BioArctic, both in Sweden, have combined STED microscopy, a technology that allows super-resolution visualization, and a new antibody recently created to observe the amyloidogenic aggregates characteristic of Alzheimer's disease.

12 Oct 2023

Scientists Gain Insights into Biophysical Properties of Neurons with New Workflow

Biophysically detailed neuronal models provide a unique window into the workings of individual neurons.

5 Oct 2023

Jellyfish are More Advanced Than Previously Thought

The enormous evolutionary success of jellyfish is clear after more than 500 million years on Earth. Nonetheless, they were always seen as primitive creatures with limited learning ability.

25 Sep 2023

Fruit Flies Show How Brain Reward-Based Decisions Work

Fitzgerald’s brother-in-law, like many L.P. record collectors, has a go-to store where he routinely finds the greatest vinyl for his collection.

25 Sep 2023

Bioprinted Neural Networks Mimic Brain Circuitsdani

Researchers from Monash University’s Engineering Department have achieved a significant breakthrough by using “bioinks” that include living nerve cells (neurons) to 3D print nerve networks.

22 Sep 2023

Brain's Choreography of Movement Unveiled in Zebrafish Study

The zebrafish brain, though simpler than its human counterpart, is a complex network of neurons that engage in a ceaseless dance of electrical activity.

11 Sep 2023

Bats' Navigation Brain Cells Also Encode Social Information

The same neurons that help bats navigate through space may also help them navigate collective social environments, finds a new study published today in the journal Nature.

31 Aug 2023

Scale Biosciences Continues Commercial Expansion with Introduction of New and Differentiated Single Cell Methylation and Single Cell RNA Sequencing Solutions

Scale Biosciences, Inc. (ScaleBioTM), an innovator in single cell sequencing leveraging combinatorial indexing technologies, today announced an expansion of their product portfolio to enable a broader range of single cell omics experiments and unlock new translational research applications.

30 Aug 2023