Protein News and Research

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Proteins are complex molecules that are made up of amino acids. They can be found in every cell in the body, and carry out vital processes that keep human beings alive. Mutations in proteins can lead to a multitude of diseases, the most common being cancer.

New Insights Into the Antibacterial Function of GBP1 Proteins

An essential part of the human body's defense mechanism against infections is the protein GBP1.

14 Oct 2024

De Novo Antibody Protein Sequencing Reveals Novel Functional and Neutralizing Antibodies Post-SARS-CoV-2 Vaccination

Rapid Novor has published a study that highlights the power of combining de novo antibody protein sequencing with conventional proteomics to uncover functional and neutralizing antibodies in human plasma following SARS-CoV-2 vaccination.

From Rapid Novor Inc 14 Oct 2024

Researchers Develop Fluorescent Biosensor to Study PKC Activity

Working in organoid models, researchers at University of California San Diego School of Medicine have developed a new tool to study protein-kinase C (PKC) enzymes, which play a critical role in cell growth, differentiation and survival.

14 Oct 2024

Unveiling the Protective Role of KLF6 in Diabetic Kidney Disease

Research by Stony Brook Medicine nephrology specialists may help prevent or reduce diabetic kidney disease progression by targeting cellular signaling between kidney cells and inducing a specific gene.

11 Oct 2024

New Discovery Reveals How MX Protein Traps HIV and Herpes Viruses

A group of researchers led by Xavier Saelens and Sven Eyckerman at the VIB-UGent Center for Medical Biotechnology discovered how a protein linked to the human immune system wards off HIV-1 and herpes simplex virus-1 by assembling structures in the cell that lure in these viruses and then trap them or even take them apart.

11 Oct 2024

AI Uncovers Over 160000 New RNA Virus Species

Artificial intelligence (AI) has been used to reveal details of a diverse and fundamental branch of life living right under our feet and in every corner of the globe.

10 Oct 2024

New Method for Identifying Kinase Inhibitors for Cancer Therapy

The most difficult subtype of breast cancer to treat is triple-negative breast cancer (TNBC). Over 20,000 cases of TNBC are reported each year in the United States alone.

10 Oct 2024

Researchers Develop Highly Selective SARS-CoV-2 Mpro Inhibitors

New research from The Wistar Institute's Salvino lab -; led by professor Joseph Salvino, Ph.D. -; has identified a novel series of SARS-CoV-2 Mpro inhibitors that may lead to potential new COVID-19 treatments that, according to preclinical testing, effectively inhibits COVID-19 and synergizes with existing anti-COVID therapies.

9 Oct 2024

Engineering Tissue Domains with a Synthetic Biology Approach

Researchers at Nano Life Science Institute (WPI-NanoLSI), Kanazawa University, demonstrate how morphogens combined with cell adhesion can generate tissue domains with a sharp boundary in an in vitro model system.

9 Oct 2024

Study Unravels the Mystery of Hsp70 Chaperones

Proteins control most of the body's functions, and their malfunction can have severe consequences, such as neurodegenerative diseases or cancer. Therefore, cells have mechanisms in place to control protein quality.

9 Oct 2024

Unveiling the Enzymatic Riches of Spider Venoms

Spiders, as venomous creatures, employ their chemical arsenal for prey acquisition or self-defense. Their venom contains small neurotoxins that target the central nervous system of their targets.

8 Oct 2024

Bioengineered Bacteria with Mussel-Like Adhesion Could Clean Up Plastic

Researchers at Rice University have created bioengineered microbes with strong adhesion that have the potential to revolutionize environmental cleanup by drawing on nature's genius for adhesives, the sticky power of mussels.

8 Oct 2024

Scientists Uncover Secrets of Circadian Rhythm Control

Scientists from Duke-NUS Medical School and the University of California, Santa Cruz, have discovered the secret to regulating our internal clock.

8 Oct 2024

Microbial Enzyme From Sewage Sludge Offers Hope for Plastic Waste Reduction

Plastic pollution is everywhere, and a good amount of it is composed of polyethylene terephthalate. This polymer is used to make bottles, containers and even clothing.

4 Oct 2024

Genes2Genes Unlocks New Potential for Detecting Gene Expression Changes

Genes2Genes an accurately infer alignments in simulated and real datasets of single-cell trajectories and capture sequential mismatches and matches in individual genes.

4 Oct 2024

Mapping the Complex Structure and Function of CRISPR-Cas Protein Scissors

CRISPR-Cas systems help to protect bacteria from viruses. Several different types of CRISPR-Cas defense systems are found in bacteria, which differ in their composition and functions.

3 Oct 2024

Discovering New Drug Targets Through Paralog Hopping

Some proteins in the human body are easy to block with a drug; they have an obvious spot in their structure where a drug can fit, like a key in a lock. But other proteins are more difficult to target, with no clear drug-binding sites.

3 Oct 2024

Structural Discovery of Fanzor Proteins Offers New Directions in Genome Engineering

A revolution in biomedicine is currently underway, driven by the application of genome engineering tools such as the prokaryotic CRISPR-Cas9.

3 Oct 2024

A New Understanding of Chromatin Regulation and its Implications

Human survival is dependent upon an extraordinarily intricate dance that takes place inside every cell and every nucleus. DNA is continually being wrapped and unwrapped by proteins, and even small mistakes might result in cancer.

3 Oct 2024

New Insights into U1 Snrnp Functions in Plant Splicing Mechanisms Using Arabidopsis

U1 snRNP interactions in Arabidopsis highlight its dual role in splicing and mRNA regulation, essential for maintaining transcript integrity and growth.

2 Oct 2024