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Genome-Wide Study Identifies Gene Pair Crucial for Regulating Blood Vessel Disease in the Lungs

University of Pittsburgh Schools of Medicine researchers uncovered a fundamental mechanism that controls the body's response to limited oxygen and regulates blood vessel disease of the lung.

16 Jan 2024

Mosaic Turner Syndrome Identified in 2500-Year-Old Briton: Ancient DNA Reveals Hidden History

Researchers at the Francis Crick Institute, working with University of Oxford, University of York and Oxford Archaeology, have developed a new technique to measure the number of chromosomes in ancient genomes more precisely, using it to identify the first prehistoric person with mosaic Turner syndrome (characterized by one X chromosome instead of two [XX]), who lived about 2500 years ago.

16 Jan 2024

Algal Blooms May Pose More Health Risks Than Previously Thought

Florida's 156-mile-long Indian River Lagoon (IRL) borders five different counties and has five inlets that connect the lagoon with the Atlantic Ocean.

16 Jan 2024

Honeybees Directly Provide Nutrients to Gut Bacteria

Bacteria have adapted to all terrestrial environments. Some have evolved to survive in the gut of animals, where they play an important role for their host; they provide energy by degrading indigestible food, they train and regulate the immune system, they protect against invasion by pathogenic bacteria, and they synthesize neuroactive molecules that regulate the behavior and cognition of their host.

16 Jan 2024

Using a Data-Driven Approach to Accelerate the Design Process for New Drugs

Researchers have developed a platform that combines automated experiments with AI to predict how chemicals will react with one another, which could accelerate the design process for new drugs.

16 Jan 2024

Genome Analysis Exposes How Fungal Infections Evade Drugs

Global fungal infections, which affect one billion people and cause 1.5 million deaths each year, are on the rise due to the increasing number of medical treatments that heighten vulnerability.

16 Jan 2024

Messenger RNA Therapy Could be Used to Correct Rare Liver Genetic Disease

By exploiting the technology used in Covid-19 vaccines, a team led by UCL, King's College London and Moderna scientists has created an effective therapy for a rare disease, in a study in mice, demonstrating the technology's potential therapeutic use in people.

16 Jan 2024

Breakthrough 3D Vascular Sheet Mimics Atherosclerosis for High-Throughput Drug Screening

A groundbreaking 3D, three-layer nanomatrix vascular sheet that possesses multiple features of atherosclerosis has been applied for developing a high-throughput functional assay of drug candidates to treat this disease, University of Alabama at Birmingham researchers report in the journal Biomaterials.

16 Jan 2024

Live-Cell Imaging Reveals How STING Activates Innate Immunity

When pathogens attack the body, the innate immune system goes to work protecting against the invading disease.

12 Jan 2024

EBV-Targeting T-Cells Linked to Early MS Damage

The body's immune response to Epstein-Barr virus (EBV) may play a role in causing damage in people with multiple sclerosis, according to a new study led by UTHealth Houston.

12 Jan 2024

Simple Blood Test Uncovers Gene Expression Secrets

The brain is the most protected organ in the body, sheathed in a complex and nearly impenetrable barrier of specialized blood vessels.

12 Jan 2024

Genetic Analysis Unlocks Secrets of Previously Unknown Bacteria

Unknown germs are a common occurrence in hospitals. Researchers at the University of Basel have spent many years collecting and analyzing them.

12 Jan 2024

Unlocking Precise DNA Modifications With Cas12a Innovations

Caixia Gao’s group at the Chinese Academy of Sciences’ Institute of Genetics and Developmental Biology has created a number of new prime editors based on the Cas12a protein, broadening the applications and targeting range of precision genome editing, as reported in a study published in Nature Biotechnology.

12 Jan 2024

Understanding Thermal Stress Response in Corals Species

For the first time, scientists have identified a single-celled microbe that can protect corals from ocean warming-related events like bleaching.

12 Jan 2024

Preventing Immunological Rejection Following Transplantation

According to researchers, genetically modified stem cells may also open the door to novel regenerative medicine therapies for conditions including Type 1 diabetes.

12 Jan 2024

Human Conjunctiva Model Developed For First Time

The Hubrecht Institute's Organoid group created the first organoid model of the human conjunctiva. The function of these organoids is mimicked by the human conjunctiva, a tissue involved in the formation of tears.

12 Jan 2024

Streamlined Laboratory Integration With INTEGRA’s Electronic and Automated Liquid Handling Solutions

Rapid technological advancements in the life sciences field have made automation a key focus for many laboratories, and INTEGRA Biosciences is proud to provide advanced liquid handling solutions to streamline laboratory protocols.

From INTEGRA Biosciences 11 Jan 2024

Unexpected Situations Trigger Chandelier Cell Activity

According to a recent study from the Netherlands Institute for Neuroscience, certain brain cells, known as chandelier cells, become active in unexpected circumstances.

11 Jan 2024

Decoding the Phylogeny of Popular and Poisonous Mushrooms

The Kunming Institute of Botany, Chinese Academy of Sciences research group on fungal diversity and molecular evolution worked with colleagues both domestically and abroad to perform genome skimming of fungal specimens from the genera Tricholomopsis, Sarcomyxa, Macrotyphula, Phyllotopsis, and other related groups.

11 Jan 2024