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Analyzing how disease-causing fungi become resistant to antifungal drugs

An investigation has been performed by scientists as to how disease-causing fungi become resistant to antifungal drugs to help avoid possibly detrimental impacts of the growing resistance harmful microbes are developing to drugs.

31 Jan 2023

Tweezers illustrate how chemotherapy affects DNA

A recent study from Cornell University offers a new perspective on how the chemotherapy agent etoposide delays and kills vital enzymes that support the growth of cancer cells.

31 Jan 2023

Novel, more accurate computational tool for long-read RNA sequencing developed

On the journey from gene to protein, a nascent RNA molecule can be cut and joined, or spliced, in different ways before being translated into a protein.

31 Jan 2023

Anti-aging gene found in centenarians can rewind the heart's biological age by 10 years

An anti-aging gene discovered in a population of centenarians has been shown to rewind the heart's biological age by 10 years.

31 Jan 2023

Researchers discover new type of pathogenic fungus that infects potatoes

RUDN University biologists have discovered a new type of pathogenic fungus that infects potatoes and leads to massive crop loss.

31 Jan 2023

Proteins’ movement and the spread of antibiotic resistance

Umeå University researchers have figured out how a particular type of protein travels during DNA replication. The discovery could affect the current understanding of how bacteria propagate antibiotic resistance genes.

30 Jan 2023

Cryo-EM helps visualize the detailed structure of viral genome replication machinery

RNA viruses, such as the coronavirus that causes COVID-19, are in a life-and-death race the moment they infect a cell.

30 Jan 2023

Newly discovered genetic mutation may be a root cause of severe cases of childhood glaucoma

An international team of scientists led by Mass Eye and Ear, a member of Mass General Brigham, and Boston Children's Hospital, has discovered a new genetic mutation that may be a root cause of severe cases of childhood glaucoma, a devastating condition that runs in families and can rob children of their vision by 3 years of age.

30 Jan 2023

Collaboration across European countries accelerates the characterization of an emergent plant virus

In the 21st century, "collaboration" has become a popular buzzword, but effectively working together across disciplines and countries is easier said than done.

27 Jan 2023

Deep-learning model for zinc finger design allows reprogramming of human transcription factors

Researchers at the University of Toronto and New York University have developed a novel technology that can engineer proteins to target any stretch of DNA in the human genome, opening a door toward gene therapies for a broader range of health conditions.

27 Jan 2023

Analysis of pancreatic cancer's microenvironment reveals cause of tumor cell resistance to immunotherapy

A new study that analyzed the tumor microenvironment of pancreatic cancer revealed the cause of tumor cell resistance to immunotherapy and resulted in new treatment strategies.

27 Jan 2023

Gene editing made faster than ever before using AI

The first simple production of customizable proteins known as zinc fingers to treat diseases by turning genes on and off might be enabled with the help of an artificial intelligence (AI) program.

From New York University (NYU) 27 Jan 2023

Persistent tumor mutation load may help predict outcome of novel immunotherapies

Cancer experts have tried, sometimes unsuccessfully, to use the total number of mutations in a tumor, called the tumor mutation burden (TMB), to predict a patient's response to immunotherapy.

27 Jan 2023

Researchers use artificial human skin to block invasive tumor growth in skin cancer model

By using artificial human skin, a research group from the University of Copenhagen have managed to block invasive growth in a skin cancer model.

27 Jan 2023

Revealing the propagation of singlet oxygen along double stranded DNA

Nucleic acid-targeting photodynamic therapy (PDT) is an innovative type of targeted therapy that is currently being studied. This treatment is based on photosensitizers, which are drugs that attach to specific regions in a cell’s DNA.

26 Jan 2023

Enhancing the efficacy of CRISPR/Cas9 and related methods

The effectiveness of molecular genetic techniques like CRISPR/Cas9 and related systems has been significantly improved, and their range of applications has been expanded, by researchers from the Department of Developmental Biology/Physiology at the Centre for Organismal Studies of Heidelberg University.

26 Jan 2023

Researchers use supercomputer to unveil new methods for DNA mosaic recognition

As humans, we each have trillions of cells. And each cell has a nucleus with individual genetic information –DNA – that can mutate to create an abnormality.

25 Jan 2023

Understanding the biochemical, ecological and physiological plant responses to heat and drought

The team of international scientists suggest that it is critical to understand the biochemical, ecological and physiological responses on plants to the stresses of heat and drought in order for more practical solutions and management.

25 Jan 2023

New genetic condition that raises vulnerability to opportunistic infections

An international consortium co-led by Vanderbilt University Medical Center immunogeneticist Rubén Martínez-Barricarte, PhD, has discovered a new genetic disorder that causes immunodeficiency and profound susceptibility to opportunistic infections including life-threatening fungal pneumonia.

24 Jan 2023

New computational tool for long-read RNA sequencing

An evolving RNA molecule can be cut and joined, or spliced, in various ways on the path from gene to protein before being translated into a protein. Using a technique called alternative splicing, multiple proteins can be encoded by a single gene.

24 Jan 2023

Genetic News and Research

Analyzing how disease-causing fungi become resistant to antifungal drugs

Tweezers illustrate how chemotherapy affects DNA

Novel, more accurate computational tool for long-read RNA sequencing developed

Anti-aging gene found in centenarians can rewind the heart's biological age by 10 years

Researchers discover new type of pathogenic fungus that infects potatoes

Proteins’ movement and the spread of antibiotic resistance

Cryo-EM helps visualize the detailed structure of viral genome replication machinery

Newly discovered genetic mutation may be a root cause of severe cases of childhood glaucoma

Collaboration across European countries accelerates the characterization of an emergent plant virus

Deep-learning model for zinc finger design allows reprogramming of human transcription factors

Analysis of pancreatic cancer's microenvironment reveals cause of tumor cell resistance to immunotherapy

Gene editing made faster than ever before using AI

Persistent tumor mutation load may help predict outcome of novel immunotherapies

Researchers use artificial human skin to block invasive tumor growth in skin cancer model

Revealing the propagation of singlet oxygen along double stranded DNA

Enhancing the efficacy of CRISPR/Cas9 and related methods

Researchers use supercomputer to unveil new methods for DNA mosaic recognition

Understanding the biochemical, ecological and physiological plant responses to heat and drought

New genetic condition that raises vulnerability to opportunistic infections

New computational tool for long-read RNA sequencing

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