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Changes in Gut Microbiomes of Astronauts May be Linked to Bone Loss

In space, the bone density of both the human astronauts and rodent variety decreases. Scientists published this study on April 19th, 2023, in the journal Cell Reports. It says that alterations to the gut microbiomes of space travelers may be linked to this bone loss.

21 Apr 2023

Sickle Cell Disease Cure? Prime Editing Offers Hope for Blood Disorder

At St Jude Children’s Research Hospital and the Broad Institute of MIT and Harvard, researchers have shown how prime editing could help correct the mutation that results in sickle cell disease in a possibly curative method.

18 Apr 2023

Prime Target for Male Contraceptive Development Identified

As far as a highly effective, reversible, and non-hormonal male contraceptive for humans and animals is concerned, the discovery of a gene in multiple mammalian species could set the stage.

18 Apr 2023

Genetic Changes Affecting Cartilage Cell Maturation may Influence Adult Height, Study Shows

When it comes to height, our fate is sealed along with our growth plates—cartilage near the ends of bones that hardens as a child develops.

17 Apr 2023

Novel 3D Bioink Induces Organ Regeneration

The advancement of biomaterials for artificial organs and tissues is active due to the rise in accidental injuries and chronic diseases, together with the entry into a super-aged society.

17 Apr 2023

Insights into mechanisms impacting NSCLC disease progression

Proteomics is the study and analysis of proteins in a biological system, including their structures, functions, associations, and alterations.

5 Apr 2023

Neutrophils can affect the success of immunotherapy in treating cancer, study shows

Cancer immunotherapies that recruit a patient's own immune system to destroy tumors have transformed the treatment of many types of cancer. Yet these therapies do not elicit universally good treatment responses.

31 Mar 2023

Additional therapeutic maneuver may be needed to stop some metastasized tumors Cancer That...

Cancer that has spread to areas like the lungs can apply the brakes to a natural pathway that should recruit killer T cells directly to where it has metastasized, scientists report.

29 Mar 2023

Innovative new approach to constructing a nose in young patients with arhinia

Congenital arhinia (meaning patients born without a nose) is a rare condition associated with high mortality if not identified.

24 Mar 2023

Stem cells must take out the trash to protect against age-related diseases

In humanity's ongoing quest for the elixir of life, the science keeps pointing to stem cells. Research increasingly shows that maintaining stem cell fitness promotes a long healthspan, and new findings show keeping stem cells clean and tidy is an integral step.

22 Mar 2023

Key Hox genes control stem cells involved in bone formation and repair

A new study discovered that genes that have long been known to regulate bone formation before birth also govern bone healing later in life.

From New York University (NYU) 21 Mar 2023

Using a programmable control switch to deliver therapeutic RNA molecules to target cells

Using an RNA sensor, MIT engineers have designed a new way to trigger cells to turn on a synthetic gene.

17 Mar 2023

Study pinpoints a splicing deregulation that causes therapeutic vulnerability in pediatric AML

Pediatric acute myeloid leukemia or pAML is a childhood blood cancer, one that has proved confounding to clinicians and researchers, with a high relapse rate and relatively few identified genetic mutations (compared to the adult version) that might explain its cause.

8 Mar 2023

Revolutionary drug blocks a gene associated with driving the spread of bone cancer

Researchers at the University of East Anglia have developed a new drug that works against all of the main types of primary bone cancer.

8 Mar 2023

Using nanoparticles to carry drugs across the blood-brain barrier

Brain tumors are notoriously hard to treat. One reason is the challenge posed by the blood-brain barrier, a network of blood vessels and tissue with closely spaced cells.

3 Mar 2023

Gaining insights into the muscle damage protective effect

Loss of muscle strength can be one of the most damaging outcomes when someone is unable to move a part of their body for a long period of time.

2 Mar 2023

Cell therapy trial promises long-term improvement for patients with chronic heart failure

Physician-scientists at The Texas Heart Institute announced today the results of the largest cell therapy trial to date in patients with chronic heart failure due to low ejection fraction.

28 Feb 2023

CD5-expressing dendritic cells help to prime T cell responses against cancer

Immunotherapy has transformed cancer care. In advanced melanoma, for example, the most fatal form of skin cancer, the five-year survival rate has risen from less than 10% to more than 50% since immunotherapy was introduced in 2011.

17 Feb 2023

Improved efficacy of advanced genome editing with machine learning

Researchers at the Wellcome Sanger Institute have developed a new tool to estimate the probability of successfully introducing a gene-edited DNA sequence into a cell’s genome using the prime editing method.

17 Feb 2023

Effect of prune supplementation on the gut microbiome of postmenopausal women

New research published in the journal Food & Function indicates that daily prune consumption may improve the gut fecal microbiome of postmenopausal women. The fecal microbiome – the ecosystem of microorganisms found in one's fecal matter – reflects an individual's overall gut health. Results from the study showed notable enrichment in bacteria from the family Lachnospiraceae. This group of bacteria has been associated with an ability to decrease inflammatory markers in the body and help maintain the integrity of the gut barrier.

16 Feb 2023

Bone News and Research

Changes in Gut Microbiomes of Astronauts May be Linked to Bone Loss

Sickle Cell Disease Cure? Prime Editing Offers Hope for Blood Disorder

Prime Target for Male Contraceptive Development Identified

Genetic Changes Affecting Cartilage Cell Maturation may Influence Adult Height, Study Shows

Novel 3D Bioink Induces Organ Regeneration

Insights into mechanisms impacting NSCLC disease progression

Neutrophils can affect the success of immunotherapy in treating cancer, study shows

Additional therapeutic maneuver may be needed to stop some metastasized tumors Cancer That...

Innovative new approach to constructing a nose in young patients with arhinia

Stem cells must take out the trash to protect against age-related diseases

Key Hox genes control stem cells involved in bone formation and repair

Using a programmable control switch to deliver therapeutic RNA molecules to target cells

Study pinpoints a splicing deregulation that causes therapeutic vulnerability in pediatric AML

Revolutionary drug blocks a gene associated with driving the spread of bone cancer

Using nanoparticles to carry drugs across the blood-brain barrier

Gaining insights into the muscle damage protective effect

Cell therapy trial promises long-term improvement for patients with chronic heart failure

CD5-expressing dendritic cells help to prime T cell responses against cancer

Improved efficacy of advanced genome editing with machine learning

Effect of prune supplementation on the gut microbiome of postmenopausal women

Driving Support for Pharmaceutical Testing Through Continuous Innovation

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