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New Guidelines Enhance Accuracy of DNA-Protein Interaction Studies

Researchers at University of California San Diego have published new guidelines that could help scientists significantly improve their results when quantifying the interactions between DNA and proteins.

17 Sep 2024

PKN Inhibition Reduces Cardiac Fibrosis and Improves Heart Function

The number of people suffering from heart failure is rising quickly as society ages. Heart failure progression is linked to fibrosis, or the overgrowth of fibrotic tissue in the heart.

16 Sep 2024

New Guidelines for Accurate Spike-In Normalization in DNA-Protein Interaction Studies

New criteria developed by researchers at the University of California San Diego may greatly enhance the accuracy of results obtained by scientists when assessing the interactions between proteins and DNA.

16 Sep 2024

Innovative Approach Supercharges T Cells by Transferring Healthy Mitochondria

Fighting cancer is exhausting for T cells. Hostile tumor microenvironments can drain their mitochondrial activity, leading to a condition known as T cell exhaustion.

16 Sep 2024

Study Reveals How Alternative Splicing Regulates Plant Metabolite Production

A recent study highlights the pivotal role of alternative splicing in controlling plant secondary metabolism, which is crucial for producing bioactive compounds with significant medicinal and industrial value.

14 Sep 2024

CRISPR and Antibodies Offer New Hope for Improving CAR-T Cell Therapy Outcomes

Mayo Clinic researchers mined the molecular foundations of cancer and uncovered a new reason chimeric antigen receptor (CAR-T cell therapy) fails in some patients.

13 Sep 2024

A Novel Method for Incorporating Non-Canonical Amino Acids into Proteins

Every basic biology lesson teaches that proteins are made up of combinations of 20 distinct amino acids, which are ordered in various patterns similar to words.

12 Sep 2024

A Powerful New Tool for Biomedical Research

Scientists at Weill Cornell Medicine in Qatar (WCM-Q) have built a comprehensive molecular map of the human body and its complicated physiological processes by analyzing thousands of molecules found in 391 volunteers' blood, urine, and saliva samples.

12 Sep 2024

Global Ocean Microbiome Catalogue Opens New Frontiers In Marine Bioprospecting

Recent advancements in sequencing have led to the GOMC, a comprehensive catalog of marine microbiomes, enhancing prospects for biotechnological applications.

12 Sep 2024

Genetic Blueprint of Atractylodes Lancea Reveals Key Insights for Medicinal Use

Scientists have decoded the genetic blueprint of Atractylodes lancea, a prized herb in traditional Chinese medicine.

12 Sep 2024

Developing Techniques for Imaging Biomolecules

Scientists are working to create quicker, more quantitative, and more publicly available methods of seeing biomolecules in living cells to speed up biotechnology discoveries, such as the production of lifesaving drugs.

11 Sep 2024

Monoclonal Antibody SC27 Shows Broad Effectiveness Against SARS-CoV-2 Variants

A monoclonal antibody appears effective at neutralizing the numerous variants of SARS-CoV-2, as well as related viruses in animals that could pose a threat if they were to begin spreading in people.

10 Sep 2024

New Insights into RNA Export Mechanisms in Drosophila Revealed

Eukaryotic cells are complex biological units, each with multiple membrane-bound compartments. These cells use specialized mechanisms to export biomolecules from their synthesis site to where they function.

10 Sep 2024

Study Unveils How Bacteria Thrive Within the Nucleus of Deep-Sea Mussels

Most animals live in intimate relationships with bacteria. Some of these bacteria live inside the cells of their hosts, but only very few are able to live inside cell organelles (structures inside the cell, like organs in the body).

9 Sep 2024

Breakthrough Nanoparticle Therapy Boosts Immune Response Against Aggressive Pancreatic Cancer

Innovative use of lipid nanoparticles to deliver immune agonists shows promise in activating anti-tumor immunity in pancreatic ductal adenocarcinoma models.

9 Sep 2024

From Bone Regeneration to Heart Repair: Stem Cell Transplantation Paves the Way for New Medical Frontiers

Stem cell transplantation offers promising solutions for tissue regeneration and age-related degeneration, despite challenges in safety and production costs.

9 Sep 2024

Study Reveals How Damaged Cells Contribute to Chronic Kidney Disease Progression

A study published in Nature Communications provides new insight into how damaged cells interact within disease-promoting microenvironments following acute kidney injury, or AKI.

6 Sep 2024

LSTM Research Identifies 91 RNA Viruses in Parasitic Worms

New research shows that parasitic nematodes, responsible for infecting more than a billion people globally, carry viruses that may solve the puzzle of why some cause serious diseases.

5 Sep 2024

New Study Identifies Key Protein Influencing Longevity

It turns out that a particular gene has a great influence on longevity, a new study from the University of Copenhagen concludes. This may pave the way for new treatment.

5 Sep 2024

Study Reveals Immune Cells' Role in Lung Scarring After Viral Infections

Investigators involved in a multicenter study co-led by Cedars-Sinai discovered a pathway by which immune cells prevent the lungs' protective barrier from healing after viral infections like COVID-19.

5 Sep 2024