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Study Identifies Risk Genes and Regulatory Variants for Colorectal Cancer by Integrating Multi-Omics Data

This study was led by Prof. Xiao-Ping Miao' team from the School of Public Health, Wuhan University, in collaboration with Prof. Shaokai Zhang from the Henan Cancer Hospital.

2 Nov 2023

Genetics can Improve the Diagnostic Value of Cyanobacterial Biomarkers

Cyanobacteria are a key species in Earth's history, as they introduced atmospheric oxygen for the first time. The analysis of their evolution therefore provides important insights into the formation of modern aerobic ecosystems.

30 Oct 2023

Unraveling the Impact of Genetic Mutations on Future Generations

Regarding the structure of the human genome, it is only a matter of time until detrimental genes, which have the potential to jeopardize future generations, emerge within a population.

26 Oct 2023

Shark Survival Through the Ages: Unveiling Genetic Secrets

Sharks, having thrived for millions of years, exhibit a rare susceptibility to cancer while displaying heightened sensitivity to environmental shifts.

24 Oct 2023

Reassessment of the Role of Background Mutations in Genome Editing

More than a thousand years ago, tomatoes evolved through natural mutations. After human evolution, they cherry-picked tomatoes with preferred traits.

20 Oct 2023

Study Links Autism Gene to Broad Spectrum of Molecular and Cellular Defects

Researchers have used CRISPR gene editing, stem cells and human neurons to study the impact of a gene that is commonly mutated in autism.

6 Oct 2023

Research Offers a Promising Avenue for Improving T-Cell-Based Cancer Therapies

Using laboratory-grown cells from humans and genetically engineered mice, scientists at Johns Hopkins Medicine say they have evidence that modifying a specific protein in immune white blood cells known as CD8+ T cells can make the cells more robust, potentially opening the door for better use of people's own immune system T cells to fight cancer.

4 Oct 2023

Scientists Explain How Enhancer Reprogramming Promotes Tumor Cell Growth

Cancer cells can boost tumor development by hijacking enhancer DNA, which is typically utilized when tissues and organs form, according to researchers at the University of Toronto (U of T).

29 Sep 2023

Discovering the Key Molecule Involved in Bacterial Locomotion

A research team led by Professor Emeritus Michio Homma and Professor Seiji Kojima from the Graduate School of Science at Nagoya University, in partnership with Osaka University and Nagahama Institute of Bio-Science and Technology, has gained fresh insights into the mechanism of bacterial locomotion.

20 Sep 2023

NICER Gene Editing Technique Reduces Unintended Mutations

The gene editing technique CRISPR/Cas9 has allowed researchers to make precise and impactful changes to an organism's DNA to fix mutations that cause genetic disease.

15 Sep 2023

Pusan National University Scientists Explore OsMATL2 Gene as a Candidate for Haploid Induction in Rice

Double haploid technology can dramatically accelerate crop breeding with specifically chosen genetic traits.

13 Sep 2023

Genomic Surveillance Finds Malaria-Causing Parasites Resistant to Treatments

Scientists have discovered new strains of malaria-causing parasites in Ethiopia that are both resistant to current treatments and evade detection by common diagnostic tests—a development that could increase malaria cases and deaths while making eradicating the disease even more difficult.

12 Sep 2023

LJI Scientists Harness 'Helper' T Cells To Treat Tumors

Scientists are on the hunt for a unique set of mutations, called "neoantigens," that let the immune system distinguish tumor cells from normal cells. Their goal is to help the immune system react to neoantigens and target tumor cells for destruction.

4 Sep 2023

NEUROG3 Gene Plays Key Role in Pancreas Development

Different cells in the human pancreas play important roles in blood sugar regulation. Neurogenin 3 (NEUROG3) is a gene found in pancreatic cells.

1 Sep 2023

Sensory Neurons Develop Customized Nerve Endings Based on Cues From the Skin, Finds Study

Nerve cells that sense touch grow the appropriate endings for hairy or hairless skin based on cues from the skin itself, rather than through predetermined programming, according to research led by Harvard Medical School scientists and published Aug. 21 in Developmental Cell.

23 Aug 2023