Organoids News and Research

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Organoids are three-dimensional cell cultures from embryonic stem cells or induced pluripotent stem cells that model important features of whole organs.

Study details replication and immune evasion of Delta SARS-CoV-2 variant

According to scientists, the Delta variant of SARS-CoV-2 has likely spread through its capability to avoid neutralizing antibodies and its heightened infectivity.

8 Sep 2021

Scientists develop lung organoids to imitate actual SARS-CoV-2 infection

The emergence of the COVID-19 pandemic in the United States in early 2020 left researchers struggling to identify lab models of SARS-CoV-2 infection.

From UC San Diego 2 Sep 2021

Researchers use prime editing to correct mutations causing cystic fibrosis in organoids

A team of scientists rectified mutations that result in cystic fibrosis in cultured human stem cells.

11 Aug 2021

Researchers use body-on-a-chip cancer models to study personalized immunotherapy response

Wake Forest researchers and clinicians are using patient-specific tumor 'organoid' models as a preclinical companion platform to better evaluate immunotherapy treatment for appendiceal cancer, one of the rarest cancers affecting only 1 in 100,000 people.

20 Jul 2021

Researchers identify key cells involved in childhood brain cancer

A new study coordinated by the University of Trento could have identified the cell of origin of medulloblastoma—a malignant tumor in children that affects the central nervous system. In this study, scientists have used organoids to replicate the tumor tissue, for the first time.

25 Jun 2021

Study finds a link between progression of Alzheimer’s disease and corpuscles in cell nuclei

Studies conducted on patients’ tissue as well as mini-brains created from stem cells have provided a better insight into Alzheimer’s disease.

15 Jun 2021

AMSBIO's custom lentivectors enable visualization of cell nuclei and F-actin cytoskeleton in organoids

AMSBIO have supplied custom lentivectors to Francesco Pampaloni and his team at the Buchmann Institute for Molecular Life Sciences in Frankfurt, Germany allowing them to visualize cell nuclei and F-actin cytoskeleton in their organoids.

From AMS Biotechnology 1 Jun 2021

Human self-organizing cardiac organoids mimic the architecture of a heart chamber

Self-organizing heart organoids created at the Austrian Academy of Sciences’ Institute of Molecular Biotechnology (IMBA) are also efficient injury and in vitro congenital disease models. These “cardioids” have the potential to transform studies into cardiovascular diseases and heart malformations.

21 May 2021

New way to study uterine fluid in the lab could avoid invasive procedures during pregnancy

The quest to create safer, more successful pregnancies is one of the top goals of modern science. While pregnancy is better understood today than ever before, with improvements in technology helping to lower the risk of negative outcomes, there is much researchers still don't know about a vital part of the pregnancy process: uterine fluid.

13 May 2021

3D-printed system enables the growth of self-organizing brain tissue

A research team has created brain tissue organoids in a tiny 3D-printed system that helps them observe as they grow and develop.

7 Apr 2021

New highly sensitive RNA detection method advances in situ transcriptomics

Human cells typically transcribe half of their roughly 20,000 genes into RNA molecules at any given time. Just like with proteins, the function of those RNA species not only relies on their abundance but also their precise localization within the 3D space of each cell.

18 Mar 2021

Researchers generate thyroid mini-organs in the lab

Hormones produced by the thyroid gland are essential regulators of organ function. The absence of these hormones either through thyroid dysfunction due to, for example, irradiation, thyroid cancer or autoimmune disease or thyroidectomy leads to symptoms like fatigue, feeling cold, constipation, and weight gain.

12 Mar 2021

New platform could help treat neurodegenerative diseases using regenerative medicine

Imagine if surgeons could transplant healthy neurons into patients living with neurodegenerative diseases or brain and spinal cord injuries.

24 Feb 2021

Researchers identify three genes regulating stemness of gastric tissue stem cells

Tissue stem cells can self-renew and differentiate, supplying cells necessary for tissues at various developmental stages.

9 Feb 2021

Scientists implicate disruption in prenatal neurogenesis in the development of autism

A new study of autism risk genes by UC San Francisco and UC Berkeley scientists implicates disruption in prenatal neurogenesis - a process in which specialized "progenitor" cells give rise to new brain cells - in the development of autism spectrum disorders (ASDs).

9 Feb 2021

Organoids News and Research

Study details replication and immune evasion of Delta SARS-CoV-2 variant

Scientists develop lung organoids to imitate actual SARS-CoV-2 infection

Researchers use prime editing to correct mutations causing cystic fibrosis in organoids

Researchers use body-on-a-chip cancer models to study personalized immunotherapy response

Researchers identify key cells involved in childhood brain cancer

Study finds a link between progression of Alzheimer’s disease and corpuscles in cell nuclei

AMSBIO's custom lentivectors enable visualization of cell nuclei and F-actin cytoskeleton in organoids

Human self-organizing cardiac organoids mimic the architecture of a heart chamber

New way to study uterine fluid in the lab could avoid invasive procedures during pregnancy

3D-printed system enables the growth of self-organizing brain tissue

New highly sensitive RNA detection method advances in situ transcriptomics

Researchers generate thyroid mini-organs in the lab

New platform could help treat neurodegenerative diseases using regenerative medicine

Researchers identify three genes regulating stemness of gastric tissue stem cells

Scientists implicate disruption in prenatal neurogenesis in the development of autism

Study provides a causal link between the Alzheimer's risk gene and COVID-19

New model can help identify potential drug targets for ulcerative colitis

Researchers create 3D miniature organs that precisely mimic human tissues

Using genetic engineering to grow synthetic livers

New breakthrough in microscopy and endoscopy may advance the field of precision medicine

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