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Scientists Create "Immunologically Silent" DNA Vaccine for Potent Virus Defense

Using a virus-like delivery particle made from DNA, researchers from MIT and the Ragon Institute of MGH, MIT, and Harvard have created a vaccine that can induce a strong antibody response against SARS-CoV-2.

31 Jan 2024

Asimov Launches LV Edge Packaging System to Optimize Lentivirus Production

Asimov, the synthetic biology company advancing the design and manufacture of therapeutics, today announced the launch of their LV Edge Packaging System, which improves the cost efficiency and reduces the supply chain risk of lentiviral production.

30 Jan 2024

Simple Blood Test Uncovers Gene Expression Secrets

The brain is the most protected organ in the body, sheathed in a complex and nearly impenetrable barrier of specialized blood vessels.

12 Jan 2024

Tracking Genes in the Brain Via Non-Invasive Methods

With its intricate network of specialized blood arteries forming a nearly impenetrable barrier, the brain is the most protected organ in the body.

11 Jan 2024

Epigenetic Key Unlocks Treatment Path for Endocrine-Resistant Breast Cancer

Endocrine resistance – a major cause of breast cancer deaths – can be underpinned by an epigenetic change called DNA methylation, researchers at the Garvan Institute of Medical Research have discovered.

10 Jan 2024

Japanese Scientists Revolutionize Regenerative Lung Medicine

Globally, chronic obstructive pulmonary disease, or COPD, is the third most common cause of mortality. It is characterized by permanent and irreversible lung damage, for which lung transplantation is the only effective treatment. Unfortunately, it is hard to find good lung donors.

8 Jan 2024

Toxic Plant Toxin Gets a Safety Upgrade for New Drugs and Pesticides

Picrotoxinin, a plant-derived toxin that Asian fishermen traditionally have used to paralyze and catch fish, has long been seen as a possible starting point for new human therapeutics and other neuroactive products.

26 Dec 2023

Fox Urine Compound Activates Multiple Sensory Pathways for Robust Insect Avoidance

Crop damage in agriculture and the transmission of vector-borne diseases by insect pests have become worldwide threat nowadays.

26 Dec 2023

The Adrenaline Puzzle Solved: Scientists Untangle Key Cell Receptor's Inner Workings

Through an international collaboration, scientists at St. Jude Children's Research Hospital leveraged data science, pharmacology and structural information to conduct an atomic-level investigation into how each amino acid in the receptor that binds adrenaline contributes to receptor activity in the presence of this natural ligand.

26 Dec 2023

New Technique Reveals Secrets of Protein Partnerships

Proteins are building blocks of our bodies, but they do not work solo. They form partners to facilitate in different biological processes that keep us going.

22 Dec 2023

Microbial Sensor Unlocks Path to Personalized Blood Stem Cell Therapy

A microbial sensor that helps identify and fight bacterial infections also plays a key role in the development of blood stem cells, valuable new insight in the effort to create patient-derived blood stem cells that could eliminate the need for bone marrow transplants.

21 Dec 2023

NUS Scientists Develop Novel Method to Identify and Sort Killer Immune Cells

Our body's immune system is a complex network of organs, cells, and proteins that work in synchrony to protect our bodies against infections caused by pathogens and fight against disease-causing changes in our body, such as the emergence of cancer cells.

20 Dec 2023

Microbial Sensor Plays Key Role in Blood Stem Cell Development

20 Dec 2023

Unveiling the Role of Exosomes in Regulating Hepatic Lipid Metabolism

Non-alcoholic fatty liver disease (NAFLD), characterized by an excess accumulation of hepatic lipids, is highly prevalent and can progress to cirrhosis and liver cancer.

12 Dec 2023

Computational Insights and Magnetic Tweezers: Unraveling Coronavirus Biomechanics

Richard Feynman is renowned for expressing, “Everything that living things do can be understood in terms of the jigglings and wigglings of atoms.”

28 Nov 2023

Unraveling Stem Cell Destiny in Intestinal Organoids

Stem cells possess the remarkable ability to differentiate and replace deceased or impaired cells within the body.

27 Nov 2023

Structural Insights Into Coronavirus Spike Proteins

Coronaviruses employ protein “spikes” to latch onto and infect cells. Contrary to their name, these spikes do not have a rigid and pointed structure. Instead, they resemble chicken drumsticks, with the meaty portion facing outward.

27 Nov 2023

Nutrient Derived From Meat and Dairy Enhances Cancer Killing Ability of Immune Cells

Trans-vaccenic acid (TVA), a long-chain fatty acid found in meat and dairy products from grazing animals such as cows and sheep, improves the ability of CD8+ T cells to infiltrate tumors and kill cancer cells, according to a new study by researchers from the University of Chicago.

27 Nov 2023

Unraveling the Mystery of L-Cry: A Distinctive Cryptochrome Protein

In a recent release in Nature Communications, a collaborative research group comprising Johannes Gutenberg University Mainz (JGU), the University of Cologne, and the University of Oldenburg has disclosed their discoveries regarding the operation of a distinctive cryptochrome protein (Cry).

16 Nov 2023

New Drug-Like Molecule Enhances Mitophagy, Protects Against Neurodegeneration

Having healthy mitochondria, the organelles that produce energy in all our cells, usually portends a long healthy life whether in humans or in C. elegans, a tiny, short-lived nematode worm often used to study the aging process.

14 Nov 2023