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NIH to renew grants to continue building the ClinGen resource

In an effort to continue building the Clinical Genome Resource, the National Institutes of Health will be renewing three awards amounting to $73.2 million over five years.

From National Human Genome Research Institute (NHGRI) 24 Sep 2021

Potential biomarkers help diagnose progressive stages of liver disease

Results of national research pinpointed potential biomarkers that could ultimately be employed for the diagnosis of progressive stages of liver disease.

23 Sep 2021

Researchers provide novel treatment target for common skin condition

Recent research indicates that a familiar inflammatory skin condition might arise due to inadequately regulated sex hormones.

23 Sep 2021

Genetic and epigenetic origin of pediatric liver cancer uncovered

Researchers at Hiroshima University have analyzed the molecular findings of almost 160 pediatric liver cancer cases and discovered molecular markers that should help to understand and treat the considerable variation in prognoses.

22 Sep 2021

Researchers seek to point a way toward a unified theory for DNA folding

At more than 2 meters long, the human DNA molecule uses intricate folding patterns to fit into cells while locally unfolding to express genes. Such phenomena, however, are difficult to measure in experiments, and theoretical frameworks explaining them continue to be at odds with one another.

22 Sep 2021

Novel T cells reside in lymph nodes and offer protection against melanoma

Immunotherapy is an advancing field but there is limited knowledge on the immunity to metastatic tumors in locations like lymph nodes.

20 Sep 2021

Study identifies vital factor involved in the evolution of the human brain

Humans have a huge and intricately folded neocortex, the reason for various intellectual abilities, setting apart humans from all other species.

17 Sep 2021

ASU receives $12.5 million for the development of new Biological Integration Institute

The National Science Foundation has announced the award of $12.5 million to Arizona State University for the development of a new Biological Integration Institute.

17 Sep 2021

Researchers describe investigations into an enigmatic group of coral-infecting microbes

In a Pearls article publishing September 16th in the open-access journal PLOS Pathogens, Patrick Keeling and colleagues at the University of British Columbia in Canada describe investigations into an enigmatic group of coral-infecting microbes.

17 Sep 2021

Genomics data helps explain the world's biggest migration of sardines

Scientists have discovered how the Sardine Run, one of the world's biggest migration events, works.

16 Sep 2021

UTHSC researcher receives grant to extend work on The Cancer Genome Atlas project

Neil Hayes, MD, MPH, director of the Center for Cancer Research at the University of Tennessee Health Science Center, is one of two principal investigators for a $1.8 million grant that extends the work of The Cancer Genome Atlas (TCGA), a groundbreaking multisite project to understand cancer at its molecular level through genome sequencing and extensive data analysis.

16 Sep 2021

Scientists develop a technique for reconstructing whole genomes on a personal computer

Scientists at the Massachusetts Institute of Technology and the Institut Pasteur in France have developed a technique for reconstructing whole genomes, including the human genome, on a personal computer.

From Massachusetts Institute of Technology (MIT) 15 Sep 2021

Jumpcode Genomics collaborates with TGen to investigate the genomic epidemiology of SARS-CoV-2

Jumpcode Genomics, a genome technology platform company focused on improving the understanding of human biology, announced today a collaboration with the Translational Genomics Research Institute (TGen), an affiliate of City of Hope, to aid investigations into the genomic epidemiology of SARS-CoV-2, the virus that causes COVID-19.

14 Sep 2021

Newly discovered RNA-guided endonucleases can be harnessed for genome editing in cells

Researchers seeking to understand the origins of CRISPR-Cas9 systems have uncovered a class of transposon-encoded RNA-guided nucleases, which they dubbed "OMEGA," that could be harnessed for genome editing in human cells.

14 Sep 2021

Study unravels the DNA repair mechanism by enzymes

A new study by researchers from the Gwangju Institute of Science and Technology in the Republic of Korea has revealed the mechanism of DNA repair by enzymes exonuclease III and polymerase I by utilizing single molecule fluorescence resonance energy transfer (smFRET)-enabled dynamic observation.

14 Sep 2021

Smoking-related DNA methylation patterns explain the variation in BMI between individuals

Smoking-related DNA methylation patterns explain around a fifth of the variation in body mass index (BMI) between individuals, according to a study publishing September 9th in the open-access journal PLOS Genetics, led by Carmen Amador at the University of Edinburgh.

13 Sep 2021

Genome News and Research

NIH to renew grants to continue building the ClinGen resource

Potential biomarkers help diagnose progressive stages of liver disease

Researchers provide novel treatment target for common skin condition

Genetic and epigenetic origin of pediatric liver cancer uncovered

Researchers seek to point a way toward a unified theory for DNA folding

Novel T cells reside in lymph nodes and offer protection against melanoma

Study identifies vital factor involved in the evolution of the human brain

ASU receives $12.5 million for the development of new Biological Integration Institute

Researchers describe investigations into an enigmatic group of coral-infecting microbes

Genomics data helps explain the world's biggest migration of sardines

UTHSC researcher receives grant to extend work on The Cancer Genome Atlas project

Scientists develop a technique for reconstructing whole genomes on a personal computer

Jumpcode Genomics collaborates with TGen to investigate the genomic epidemiology of SARS-CoV-2

Newly discovered RNA-guided endonucleases can be harnessed for genome editing in cells

Study unravels the DNA repair mechanism by enzymes

Smoking-related DNA methylation patterns explain the variation in BMI between individuals

Viruses buried in marsupials' DNA may help protect against future infections

Functional genomics can assist in molecular breeding of maize, finds study

Study imparts mechanistic understanding on early stages of human cancer

Study unearths previously unknown role of CTCF, the transcription regulator

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