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Tumor DNA in DLBCL patient's stem cells or blood can predict risk of relapse after transplant

Many patients with diffuse large B-cell lymphoma (DLBCL) can be cured by a transplant using their own blood-forming stem cells, but as many as half eventually relapse. New research led by Dana-Farber Cancer Institute scientists suggests that patients whose blood or stem cell samples harbor tumor DNA are likely to relapse.

8 Dec 2020

Researchers demonstrate strategy to control chemical reactions using antibodies

Antibodies are remarkable biomarkers: they are the cues that provide us with indications about many diseases and how our immune system counter them. Now a group of scientists from the University of Rome, Tor Vergata (Italy) has found a way to repurpose them so that they can trigger a specific chemical reaction.

8 Dec 2020

Study: CAR T cell therapy is a safe, effective therapy for high-risk large B-cell lymphoma

A study led by researchers at The University of Texas MD Anderson Cancer Center found that axi-cel, an autologous anti-CD19 chimeric antigen receptor (CAR) T cell therapy, is a safe and effective first-line therapy for patients with high-risk large B-cell lymphoma (LBCL), a group with an urgent need for new and effective treatments.

8 Dec 2020

Mice infused with CD5-deleted CAR T cells showed significant reduction in tumor size

Knocking out a protein known to stifle T cell activation on CAR T cells using the CRISPR/Cas9 technology enhanced the engineered T cells' ability to eliminate blood cancers, according to new preclinical data from researchers in the Perelman School of Medicine at the University of Pennsylvania and Penn's Abramson Cancer Center.

8 Dec 2020

Study: Blood type is not associated with effects of plant-based diet on body weight

A study published in the Journal of the Academy of Nutrition and Dietetics by researchers with the Physicians Committee for Responsible Medicine--a nonprofit of 12,000 doctors--debunks the "blood type diet" by finding that blood type was not associated with the effects of a plant-based diet on body weight, body fat, plasma lipid concentrations, or glycemic control.

7 Dec 2020

Mediterranean diet decreases the likelihood of having another heart attack

A clinical study with 1002 patients with heart disease shows the advantages of a Mediterranean diet compared to a low-fat diet.

7 Dec 2020

Scientists reveal health benefits of clonal hematopoiesis in allogeneic transplants

Clonal hematopoiesis (CH) is a recently identified condition in which mutations associated with blood cancers are detected in the blood of some healthy, usually older, individuals who don't have cancer. People with CH, while asymptomatic, have an elevated risk of developing blood cancers and other negative health outcomes, including heart attacks and strokes.

7 Dec 2020

CRISPR-based test for COVID-19 provides quick, accurate results

Imagine swabbing your nostrils, putting the swab in a device, and getting a read-out on your phone in 15 to 30 minutes that tells you if you are infected with the COVID-19 virus.

7 Dec 2020

Blackcurrants have beneficial effect on post-meal glucose response

Blackcurrants have a beneficial effect on post-meal glucose response, and the required portion size is much smaller than previously thought, a new study from the University of Eastern Finland shows.

4 Dec 2020

Specific immune mechanism in COVID-19 patients triggers inflammatory process

Researchers at the University of São Paulo (USP) in Brazil have demonstrated for the first time that in COVID-19 patients an immune mechanism known as the inflammasome participates in activation of the inflammatory process that can damage several organs and even lead to death.

3 Dec 2020

Researchers determine role of NLRP1 protein in detecting the common cold virus

The role of a protein in detecting the common cold virus and kickstarting an immune response to fight infection has been uncovered by a team of scientists from Nanyang Technological University, Singapore (NTU Singapore), the Agency for Science, Technology and Research (A*STAR) and the National University of Singapore.

From Nanyang Technological University Singapore (NTU Singapore) 3 Dec 2020

Researchers identify key target that allows cancer cells to spread more efficiently

Cancer cells spread by switching on and off abilities to sense their surroundings, move, hide and grow new tumours, a new study has found.

2 Dec 2020

Study: Gut microbiota directly shapes the makeup of human immune system

In recent years, the microbiota -- the community of bacteria and other microorganisms that live on and in the human body -- has captured the attention of scientists and the public, in part because it's become easier to study. It has been linked to many aspects of human health.

1 Dec 2020

Scientists successfully edit SIV virus from genomes of non-human primates

Taking a major step forward in HIV research, scientists at the Lewis Katz School of Medicine at Temple University have successfully edited SIV - a virus closely related to HIV, the cause of AIDS - from the genomes of non-human primates.

1 Dec 2020

KAUST researchers develop durable e-skin that can mimic natural functions of human skin

A material that mimics human skin in strength, stretchability and sensitivity could be used to collect biological data in real time. Electronic skin, or e-skin, may play an important role in next-generation prosthetics, personalized medicine, soft robotics and artificial intelligence.

30 Nov 2020

Blood News and Research

Tumor DNA in DLBCL patient's stem cells or blood can predict risk of relapse after transplant

Researchers demonstrate strategy to control chemical reactions using antibodies

Study: CAR T cell therapy is a safe, effective therapy for high-risk large B-cell lymphoma

Mice infused with CD5-deleted CAR T cells showed significant reduction in tumor size

Study: Blood type is not associated with effects of plant-based diet on body weight

Mediterranean diet decreases the likelihood of having another heart attack

Scientists reveal health benefits of clonal hematopoiesis in allogeneic transplants

CRISPR-based test for COVID-19 provides quick, accurate results

Blackcurrants have beneficial effect on post-meal glucose response

Specific immune mechanism in COVID-19 patients triggers inflammatory process

Researchers determine role of NLRP1 protein in detecting the common cold virus

Researchers identify key target that allows cancer cells to spread more efficiently

Study: Gut microbiota directly shapes the makeup of human immune system

Scientists successfully edit SIV virus from genomes of non-human primates

KAUST researchers develop durable e-skin that can mimic natural functions of human skin

Researchers explain the effectiveness of anti-diabetic drug

Could there be harmful chemicals in your household dust?

CAR T cells display signs of efficacy against hard-to-treat pediatric cancer in phase 1 trial

Using 3D mapping techniques to unravel mystery of blood stem cells

Cell survival protein could protect the kidneys from 'bystander' damage during cancer therapy

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