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Gladstone Scientists Create Intricate Map of Human T Cell Function With Base Editing

In a study of historic scale, scientists at Gladstone Institutes have created an intricate map of how the immune system functions, examining the detailed molecular structures governing human T cells using the next-generation CRISPR tool known as base editing.

14 Dec 2023

Cryo-EM Analysis Uncovers Unexpected Enzymatic Switch in Bacterial Anti-Phage System

Scientists have revealed a never-before-seen phenomenon in a protein: Alone, the enzyme processes DNA and RNA but, when bound to another protein as part of a defense system, interacts with a completely different type of compound to help bacteria commit suicide.

14 Dec 2023

Groups of Cells Act Differently to Individual Cell Units

A recent study indicates that a protein responsible for generating force in individual cells operates differently when cells are part of a collective movement.

14 Dec 2023

Shedding Light on the Brain's Reward System

A new study provides deeper insights into how the brain learns and adapts through trial and error, whether a scientist or a pup.

14 Dec 2023

Light Sensing Helps Bacteria Survive Daily Environmental Shifts

Scientists know that many bacteria have proteins that give them the ability to sense light. This ability helps some bacteria use light for energy.

14 Dec 2023

From Mice to Men: New Studies Bridge the Gap in Brain Cell Gene Expression Across Species

Despite all our cells sharing the same DNA, there are thousands of different cell types in the human brain, each with a unique structure and function.

14 Dec 2023

NSF Funds IWGSC Project to Sequence Ancient Bread Wheat Genomes for Improved Traits

The International Wheat Genome Sequencing Consortium (IWGSC) is starting a two-year project, with funding from the U.S. National Science Foundation (NSF), to mine an untapped genetic resource for wheat improvement by sequencing the genomes of ancient varieties representing the worldwide diversity of bread wheat.

14 Dec 2023

Epigenetic Changes in Insulin-Producing Cells Linked to Type 2 Diabetes Onset

Do epigenetic changes cause type 2 diabetes, or do the changes occur only after a person has become ill? A new study by researchers at Lund University provides increased support for the idea that epigenetic changes can cause type 2 diabetes.

14 Dec 2023

CRISPR Takes Probiotics to the Next Level

Humans can benefit significantly from symbiotic relationships with probiotics-;live bacteria and microorganisms that influence the gut microbiota.

14 Dec 2023

A Deep Dive Into Lab-Grown Plant Cells and Their Flavorful Brews

The time might be approaching to embrace the aroma of lab-grown coffee brewed from cultivated plant cells.

13 Dec 2023

A Computational Toolkit for Brain Imaging Analysis

A group of researchers has introduced a set of free tools designed for analyzing extensive collections of brain dissection images from brain banks worldwide.

13 Dec 2023

The Complex Dynamics of Death and Reversibility

Defining death neurologically poses a challenging task. Rather than a specific moment marking the transition from life to death, it is a process spanning several minutes, sometimes reversible under certain conditions.

13 Dec 2023

Insights from the Migratory Behavior of Mosquito Bats

According to a recent study published in the journal Biology Letters, mosquito bats possess a magnetic compass that they calibrate at sunset.

13 Dec 2023

Model Helps Researchers 'See' Proteins on AFM Substrates

By employing a computational-based approach, researchers from Kanazawa University have introduced a new method for predicting protein placement on AFM substrates.

13 Dec 2023

Understudied Brain Cell Holds Key to Glioblastoma's Immunotherapy Resistance

Glioblastoma is one of the most treatment-resistant cancers, with those diagnosed surviving for less than two years.

13 Dec 2023

FluidForm Bio 3D Bioprints Human Cardiac Tissue for Drug Development Breakthrough

FluidForm Bio, a leader in developing life-like human tissue to treat disease, shares recent advancements in building human cardiac tissues using FRESH 3D bioprinting.

13 Dec 2023

Nature-Powered Nutrient Recovery: UW-Madison Develops Innovative Manure Processing Technique

An interdisciplinary team led by University of Wisconsin–Madison scientists has developed a new technique that could help farmers extract useful nutrients such as ammonia and potassium from livestock manure to efficiently make fertilizer and other useful chemical products.

13 Dec 2023