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Toxic Plant Toxin Gets a Safety Upgrade for New Drugs and Pesticides

Picrotoxinin, a plant-derived toxin that Asian fishermen traditionally have used to paralyze and catch fish, has long been seen as a possible starting point for new human therapeutics and other neuroactive products.

26 Dec 2023

New Technique Revolutionizes the Construction of Synthetic Chromosomes

A groundbreaking new technique invented by researchers at the USC Dornsife College of Letters, Arts and Science may revolutionize the field of synthetic biology.

26 Dec 2023

Simultaneous Production of Bioplastics and High-Value Carotenoids by Multifunctional Bacteria

We often look to the smallest lifeforms for help solving the biggest problems: Microbes help make foods and beverages, cure diseases, treat waste and even clean up pollution.

26 Dec 2023

Fox Urine Compound Activates Multiple Sensory Pathways for Robust Insect Avoidance

Crop damage in agriculture and the transmission of vector-borne diseases by insect pests have become worldwide threat nowadays.

26 Dec 2023

Study Reveals Tissue-Specific Effects of JAK1 Signaling in Inflammation

Researchers at the Icahn School of Medicine at Mount Sinai have gained a deeper understanding of the nuanced roles of JAK inhibitors, or modulators, in inflammation across various cell types and tissues.

26 Dec 2023

Specialized Proliferative Cells Contribute to Epithelial Regeneration in Jellyfish

At about the size of a pinkie nail, the jellyfish species Cladonema can regenerate an amputated tentacle in two to three days -; but how? Regenerating functional tissue across species, including salamanders and insects, relies on the ability to form a blastema, a clump of undifferentiated cells that can repair damage and grow into the missing appendage.

26 Dec 2023

Researchers Discover How Microbes Enhance Fruit Fly Reproduction

For many of us, when we think of microbiomes, our first thoughts are probably about the beneficial microorganisms that live in our guts.

26 Dec 2023

Unveiling the Orchestration of Cells With Single-Cell Time Tracking

While physicists continue to argue about whether time is indeed an illusion, as Albert Einstein claimed, biologists have no doubt about its significance for understanding life as a dynamic system.

26 Dec 2023

New Tool Brings Order to Single-Cell Data Chaos

A new methodology that allows for the categorization and organisation of single-cell data has been launched. It can be used to create a harmonized dataset for the study of human health and disease.

26 Dec 2023

Scientists Unravel the Mystery of Parkinson's Disease With 3D Protein Structures

Scientists at St. Jude Children's Research Hospital revealed the complex structure of two Parkinson's disease-related proteins, both of which are implicated in late-onset cases.

26 Dec 2023

The Adrenaline Puzzle Solved: Scientists Untangle Key Cell Receptor's Inner Workings

Through an international collaboration, scientists at St. Jude Children's Research Hospital leveraged data science, pharmacology and structural information to conduct an atomic-level investigation into how each amino acid in the receptor that binds adrenaline contributes to receptor activity in the presence of this natural ligand.

26 Dec 2023

Study Elucidates How Amino Acids Turn on Cell Growth Engine

Amino acids are the building blocks of life. We obtain them from the food we eat, and the body uses them to make proteins, which in turn are used for growth, development, and a multitude of other functions.

22 Dec 2023

Cracking the Code of the Cytoplasm: How Cells Organize Protein Production

Back in 2018, the lab of Christine Mayr, MD, PhD, at Memorial Sloan Kettering Cancer Center (MSK) introduced the world to a key cellular component that had been hiding in plain sight.

22 Dec 2023

Sticky Secrets Revealed: Epithelial Cells Stick and Signal for Perfect Tissues

Australian researchers have discovered a new way that epithelial cells, which form layers in organs like the skin and stomach, attach to one another, and how they perceive growth signals at these attachments, helping them form tissues of the right size and shape.

22 Dec 2023

Gut Mitochondria Hold the Key to Balanced Fat Metabolism

The maintenance of a balanced lipid homeostasis is critical for our health. While consumption of excessive amounts of fatty foods contributes to metabolic diseases such as obesity and atherosclerosis, fat is an indispensable component of our diet.

22 Dec 2023

New Technique Reveals Secrets of Protein Partnerships

Proteins are building blocks of our bodies, but they do not work solo. They form partners to facilitate in different biological processes that keep us going.

22 Dec 2023

NEMO Protein Promotes Degradation of Harmful Alpha-Synuclein Aggregates in Parkinson's Disease

Researchers have identified a mechanism that promotes the breakdown of harmful protein deposits. If it malfunctions, it can lead to Parkinson’s disease.

21 Dec 2023

How 3D DNA Architecture Shapes Cell Fate in Early Embryos

The intricate process of duplicating genetic information, referred to as DNA replication, lies at the heart of the transmission of life from one cell to another and from one organism to the next. This happens by not just simply copying the genetic information; a well-orchestrated sequence of molecular events has to happen at the right time.

21 Dec 2023

New Insights Into the Microbiome's Influence on Kidney Stone Risk

A new study from Lawson Health Research Institute and Western University published in the journal Microbiome has found changes in the microbiome in multiple locations in the body are linked to the formation of kidney stones.

21 Dec 2023

Intermittent Energy Restriction Diet Alters Brain-Gut-Microbiome Axis

Worldwide, more than one billion people are obese. Obesity is a risk factor for cardiovascular disease, diabetes, and some cancers.

21 Dec 2023

Research News and Research

Toxic Plant Toxin Gets a Safety Upgrade for New Drugs and Pesticides

New Technique Revolutionizes the Construction of Synthetic Chromosomes

Simultaneous Production of Bioplastics and High-Value Carotenoids by Multifunctional Bacteria

Fox Urine Compound Activates Multiple Sensory Pathways for Robust Insect Avoidance

Study Reveals Tissue-Specific Effects of JAK1 Signaling in Inflammation

Specialized Proliferative Cells Contribute to Epithelial Regeneration in Jellyfish

Researchers Discover How Microbes Enhance Fruit Fly Reproduction

Unveiling the Orchestration of Cells With Single-Cell Time Tracking

New Tool Brings Order to Single-Cell Data Chaos

Scientists Unravel the Mystery of Parkinson's Disease With 3D Protein Structures

The Adrenaline Puzzle Solved: Scientists Untangle Key Cell Receptor's Inner Workings

Study Elucidates How Amino Acids Turn on Cell Growth Engine

Cracking the Code of the Cytoplasm: How Cells Organize Protein Production

Sticky Secrets Revealed: Epithelial Cells Stick and Signal for Perfect Tissues

Gut Mitochondria Hold the Key to Balanced Fat Metabolism

New Technique Reveals Secrets of Protein Partnerships

NEMO Protein Promotes Degradation of Harmful Alpha-Synuclein Aggregates in Parkinson's Disease

How 3D DNA Architecture Shapes Cell Fate in Early Embryos

New Insights Into the Microbiome's Influence on Kidney Stone Risk

Intermittent Energy Restriction Diet Alters Brain-Gut-Microbiome Axis

Driving Support for Pharmaceutical Testing Through Continuous Innovation

From Memory to Metaplasticity: Unraveling the Brain's Secrets

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

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