Allergy News and Research

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The term allergy encompasses a wide range of conditions; it is not a disease in itself. In 1906 Clemens von Pirquet was the first to describe allergies as a changed or altered reaction of the immune system in response to exposure to foreign proteins. These days the term allergy – medically termed hypersensitivity, signifies an exaggerated reaction to foreign substances.

Beautyberry leaf extract boosts drug's activity antibiotic-resistant staph bacteria

Scientists discovered a compound in the leaves of a common shrub, the American beautyberry, that boosts an antibiotic's activity against antibiotic-resistant staph bacteria. Laboratory experiments showed that the plant compound works in combination with oxacillin to knock down the resistance to the drug of methicillin-resistant Staphylococcus aureus, or MRSA.

17 Jul 2020

Psychological distress may indicate the penetration of COVID-19 virus into the central nervous system

Depressed mood or anxiety exhibited in COVID-19 patients may possibly be a sign the virus affects the central nervous system, according to an international study led by a University of Cincinnati College of Medicine researcher.

15 Jul 2020

Study suggests ways to improve antibiotic allergy registrations

Antibiotics are among the most commonly prescribed medications, but in determining the most appropriate prescription for a patient, doctors and pharmacists often rely on inaccurate records of the patient's antibiotic allergies.

15 Jul 2020

Investigational COVID-19 vaccine is safe, generates neutralizing antibody activity in healthy adults

An investigational vaccine, mRNA-1273, designed to protect against SARS-CoV-2, the virus that causes coronavirus disease 2019 (COVID-19), was generally well tolerated and prompted neutralizing antibody activity in healthy adults, according to interim results published online today in The New England Journal of Medicine.

15 Jul 2020

NIH establishes clinical trial network to test vaccines and monoclonal antibodies for COVID-19

The National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health (NIH), has established a new clinical trial network that aims to enroll thousands of volunteers in large-scale clinical trials testing a variety of investigational vaccines and monoclonal antibodies intended to protect people from COVID-19.

14 Jul 2020

Scientists discover new antiviral drug against paramyxovirus

A new antiviral drug that is effective against a broad range of human pathogens in the paramyxovirus family, such as the human parainfluenzaviruses and measles virus, has been discovered by researchers in the Institute for Biomedical Sciences at Georgia State University.

14 Jul 2020

Altimmune reports positive results on intranasal COVID-19 vaccine candidate

Altimmune, Inc., a clinical-stage biopharmaceutical company, has announced positive results from the preclinical studies conducted in mice at the University of Alabama at Birmingham of its intranasal COVID-19 vaccine candidate, AdCOVID.

14 Jul 2020

New mutation in common flu subtype helps evade immune response

Strains of a common subtype of influenza virus, H3N2, have almost universally acquired a mutation that effectively blocks antibodies from binding to a key viral protein, according to a study from researchers at Johns Hopkins Bloomberg School of Public Health.

13 Jul 2020

Expansion stress promotes immunosuppression and enhances growth of breast cancer cells

Expansion stress can have an alarming impact on breast cancer cells by creating conditions that could lead to dangerous acceleration of the disease, an interdisciplinary team of University of Alabama at Birmingham researchers has found.

10 Jul 2020

Salk researchers discover genetic 'dial' to fine-tune the immune response

The human immune system is a finely-tuned machine, balancing when to release a cellular army to deal with pathogens, with when to rein in that army, stopping an onslaught from attacking the body itself.

8 Jul 2020

BU researchers develop new way to better understand human cell communication

Researchers from Boston University School of Medicine have developed and implemented a new way to better understand how human cells communicate with each other, how this communication is disrupted in human diseases and how this can be corrected pharmacologically.

7 Jul 2020

Existing drugs could disrupt SARS-CoV-2 from hijacking cells

An international team of researchers has analyzed how SARS-CoV-2, the virus that causes COVID-19, hijacks the proteins in its target cells.

30 Jun 2020

Researchers perform room-temperature X-ray measurements on SARS-CoV-2 main protease

A team of researchers at the Department of Energy's Oak Ridge and Argonne national laboratories has performed the first room-temperature X-ray measurements on the SARS-CoV-2 main protease -- the enzyme that enables the virus to reproduce.

26 Jun 2020

Experts identify steps to expand, improve SARS-CoV-2 serology tests

More than 300 scientists and clinicians from the federal government, industry and academia published a report of their conclusions and recommendations on COVID-19 serology studies online in Immunity.

24 Jun 2020

New study shows how a protein works as 'master regulator' in the immune system

Scientists at the La Jolla Institute for Immunology have discovered a potential new way to better fight a range of infectious diseases, cancers and even autoimmune diseases.

22 Jun 2020

Study may pave the way to fight asthma and other allergic diseases

House dust mites can be found everywhere around the world. When individuals do some cleaning work, they will probably stir up some of these dust mites.

16 Jun 2020

Understanding protein-coding gene's role in IBD

A protein-coding gene associated with autoimmune diseases such as Crohn's disease and ulcerative colitis, collectively referred to as inflammatory bowel disease, or IBD, will be the focus of new research in the School of Medicine at the University of California, Riverside.

9 Jun 2020

Genomic research can help combat COVID-19

Next-generation sequencing of the COVID-19 virus is providing powerful metagenomic data, which, combined with clinical data, will inform the search for effective treatments, as reported in the peer-reviewed journal Pediatric Allergy, Immunology, and Pulmonology.

5 Jun 2020

Bacteria that live in soil and on people have widespread antibiotic-destroying genes

The latest generation of tetracyclines - a class of powerful, first-line antibiotics - was designed to thwart the two most common ways bacteria resist such drugs.

3 Jun 2020

X-ray experiments reveal antibody to block entry of SARS-CoV-2

As scientists across the globe race to develop a vaccine against SARS-CoV-2, the coronavirus that causes COVID-19, an international team led by Davide Corti at Vir Biotechnology and David Veesler at the University of Washington has been working around the clock on a complementary approach - identifying neutralizing antibodies that could be used as a preventative treatment or as a post-exposure therapy.

20 May 2020

Allergy News and Research

Beautyberry leaf extract boosts drug's activity antibiotic-resistant staph bacteria

Psychological distress may indicate the penetration of COVID-19 virus into the central nervous system

Study suggests ways to improve antibiotic allergy registrations

Investigational COVID-19 vaccine is safe, generates neutralizing antibody activity in healthy adults

NIH establishes clinical trial network to test vaccines and monoclonal antibodies for COVID-19

Scientists discover new antiviral drug against paramyxovirus

Altimmune reports positive results on intranasal COVID-19 vaccine candidate

New mutation in common flu subtype helps evade immune response

Expansion stress promotes immunosuppression and enhances growth of breast cancer cells

Salk researchers discover genetic 'dial' to fine-tune the immune response

BU researchers develop new way to better understand human cell communication

Existing drugs could disrupt SARS-CoV-2 from hijacking cells

Researchers perform room-temperature X-ray measurements on SARS-CoV-2 main protease

Experts identify steps to expand, improve SARS-CoV-2 serology tests

New study shows how a protein works as 'master regulator' in the immune system

Study may pave the way to fight asthma and other allergic diseases

Understanding protein-coding gene's role in IBD

Genomic research can help combat COVID-19

Bacteria that live in soil and on people have widespread antibiotic-destroying genes

X-ray experiments reveal antibody to block entry of SARS-CoV-2

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