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Yeast's Survival Strategy Provides Clues for Targeting Cancer Cells

The discovery of a surprising way yeast used to brew beer can survive starvation could open the door to new treatments for cancer.

17 Oct 2024

Unveiling the Potential of YY1 in Blood Cell Development and Therapy

Common lymphoid progenitors, pre-pro-B cells, pro-B cells, pre-B cells, immature B cells, and finally more mature and specialized B cells are the stages in which B cells, white blood cells that produce antibodies, develop.

17 Oct 2024

Peptide Inhibitor Could Revolutionize mRNA-Based Therapies

The new hope in the fight against diseases that cannot be cured is mRNA-based vaccinations and treatments.

17 Oct 2024

Transposable Elements Drive a Critical Transition in Early Embryogenesis

Researchers at Sinai Health have discovered that DNA elements known as transposons, which may travel throughout the genome, control a crucial stage in early human development instead of human genes.

16 Oct 2024

Scientists Identify Drug-Binding Site on FOXA1

Forkhead box protein 1 (FOXA1) is a difficult-to-target protein that is frequently involved in hormone-driven malignancies, such as those of the breast and prostate.

16 Oct 2024

Proteomics Reveals Age-Related Changes in Mouse Bone Formation

A new research paper was published on the cover of Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science), Volume 16, Issue 19 on October 12, 2024, entitled, "A proteomics approach to study mouse long bones: examining baseline differences and mechanical loading-induced bone formation in young-adult and old mice."

16 Oct 2024

Transposable Elements Are Key to Normal Progression of Embryonic Cells

A critical transition in early human development is regulated not by our own genes, but by DNA elements called transposons that can move around the genome, Sinai Health researchers have found.

16 Oct 2024

New Method Sheds Light on Bacterial Calcium Management

In human, animal, and plant cells, calcium ions play a crucial role as messengers. They support the regulation of essential functions like heartbeats, stress reactions, and nerve impulses.

15 Oct 2024

Placental Protein Levels Offer Insights into Early-Onset Preeclampsia

A potentially fatal pregnancy complication, preeclampsia is characterized by persistently elevated blood pressure, which is exacerbated when it develops early in the first trimester.

15 Oct 2024

Researchers Develop Innovative Human Macrophage Model for Disease Study

A human cell culture model of the lung's most important immune cells, alveolar macrophages, helped make a key finding that is prompting researchers to rethink the role of another immune protein in infectious disease.

15 Oct 2024

Scientists Identify Key Role of Proteasome in Cell Death

Programmed cell death protects the body against cancer and other diseases. A team of researchers led by Professor Alexander Bartelt from the Institute for Cardiovascular Prevention (IPEK) has decoded a new mechanism by which oxidative stress influences cell death.

15 Oct 2024

New Mouse Model Shows Superior Ability to Study Human Immune Response to Cancer

Immunity plays a central role in the fight against cancer. Many of the current immunotherapies aim at helping the patient's immune system to better recognize cancer cells – by using engineered antibodies – or by simply providing it with new cells, pre-equipped to search and destroy cancer. Either way, what is paramount is a deep understanding of how the immune system works and confronts tumors.

15 Oct 2024