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Merging cryo-TEM and tomography methods to reveal 3D morphology of dendrites

Documenting the lithiation process in TEM can provide a deep understanding of the electrode degradation mechanism during battery cycling, which enhances material modification for improved performance. The research was guided by Prof. Dong Su (Institute of Physics, Chinese Academy of Sciences).

15 Mar 2023

Gut microbiome may modulate the efficacy of CAR-T cell cancer immunotherapy

Scientists from German Cancer Research Center (DKFZ), together with colleagues from Germany, Israel, and the USA, have found that the gut microbiome may modulate the efficacy of CAR-T cellular immunotherapy CAR-T cells in patients with B cell lymphomas.

14 Mar 2023

Understanding the relationship between gut microbiome and CAR T-cell therapy response

Microorganisms live in or on almost every part of the human body and play an important role in the regulation of normal human processes. As a result, changes in the number or type of microorganisms, also known as the microbiome, can contribute to disease and altered responses to therapy, including cancer treatment.

14 Mar 2023

Neural-network-based image recognition models for examining SCC defects

Scientists from Tokyo Metropolitan University have used machine learning to automate the identification of defects in sister chromatid cohesion. They trained a convolutional neural network (CNN) with microscopy images of individual stained chromosomes, identified by researchers as having or not having cohesion defects. After training, it was able to successfully classify 73.1% of new images. Automation promises better statistics, and more insight into the wide range of disorders which cause cohesion defects.

14 Mar 2023

Innovative method to quickly identify bacteria in fluids

Shine a laser on a drop of blood, mucus, or wastewater, and the light reflecting back can be used to positively identify bacteria in the sample.

3 Mar 2023

Lieber Institute awarded $1 million grant to foster racial diversity across neuroscience

The Lieber Institute for Brain Development has received a $1 million, two-year grant from the Chan Zuckerberg Initiative to support the work of the African Ancestry Neuroscience Research Initiative (AANRI) to promote racial equity throughout the field of neuroscience.

28 Feb 2023

Insilico Medicine: IND application for first generative AI-designed drug for COVID-19 approved

Insilico Medicine, a clinical-stage biotech company powered by generative AI, today announces that China National Medical Products Administration (NMPA) has approved the Investigational New Drug (IND) application for ISM3312, an orally available 3CLpro inhibitor generated and designed with the support of Insilico's proprietary generative chemistry platform Chemistry42 for the treatment of COVID-19.

24 Feb 2023

Artificial intelligence creates proteins to hasten chemical reactions

Scientists have for the first time utilized machine learning to design whole new enzymes, which are proteins that quicken chemical reactions. In the realm of protein design, this is a crucial development since new enzymes can find several applications in both industrial manufacture and medicine.

23 Feb 2023

Improved efficacy of advanced genome editing with machine learning

Researchers at the Wellcome Sanger Institute have developed a new tool to estimate the probability of successfully introducing a gene-edited DNA sequence into a cell’s genome using the prime editing method.

17 Feb 2023

Pungent ginger constituent puts white blood cells on heightened alert

Ginger has a reputation for stimulating the immune system. New results from the Leibniz Institute for Food Systems Biology at the Technical University of Munich (Leibniz-LSB@TUM) now support this thesis.

15 Feb 2023

MD Anderson and Replay launch new company pioneering T cell receptor NK cell therapies

The University of Texas MD Anderson Cancer Center and Replay today announced the launch of Syena, a new oncology-focused product company pioneering T cell receptor (TCR) natural killer (NK) cell therapies.

15 Feb 2023

New platform to study the feeding behavior of mosquitoes

If watching animals feast on human blood for 30-plus hours isn't your idea of fun, don't worry. The robot can do it.

10 Feb 2023

Newly discovered gene signature accurately predicts the functioning of P53 variants

In a paper published in PNAS, Maureen Murphy, Ph.D., Deputy Director of Wistar's Ellen and Ronald Caplan Cancer Center and Ira Brind Professor and Program Leader in the Molecular & Cellular Oncogenesis Program, and team have identified a gene signature that accurately predicts the functioning of P53 variants, important information to assessing cancer risk and optimizing choices for cancer therapeutics.

7 Feb 2023

Deep learning model can accurately predict the growth of deadly brain tumors

Researchers at the University of Waterloo have created a computational model to predict the growth of deadly brain tumors more accurately.

31 Jan 2023

Using data-driven computer models to predict light emission properties of iridium-centered chemicals

More than 30 years ago, the phrase "green chemistry" emerged with the Pollution Prevention Act of 1990.

31 Jan 2023

AI-based strategy helps discover high-affinity antibody drugs

Scientists at University of California San Diego School of Medicine have developed an artificial intelligence (AI)-based strategy for discovering high-affinity antibody drugs.

31 Jan 2023

The Journal, Artificial Intelligence in the Life Sciences, Highlights the Contributions of Women in Artificial Intelligence in the Life Sciences

The journal, Artificial Intelligence in the Life Sciences (AILSCI), published by Elsevier, is set to release a special Themed Article Collection (TAC): Women in AI in the Life Sciences.

30 Jan 2023

AI develops first-ever functional artificial protein

Scientists have developed an AI system that can produce artificial enzymes from scratch. Even though several of these enzymes’ artificially generated amino acid sequences differed noticeably from those of any known natural protein, they nonetheless performed as well in laboratory testing as those found in nature.

27 Jan 2023

Researchers use supercomputer to unveil new methods for DNA mosaic recognition

As humans, we each have trillions of cells. And each cell has a nucleus with individual genetic information –DNA – that can mutate to create an abnormality.

25 Jan 2023

Study helps to understand the molecular mechanisms underlying complex taste sensations

Chicory is a popular salad ingredient, and its bitterness harmonizes well with apples or balsamic vinegar.

24 Jan 2023

Machine Learning News and Research

Merging cryo-TEM and tomography methods to reveal 3D morphology of dendrites

Gut microbiome may modulate the efficacy of CAR-T cell cancer immunotherapy

Understanding the relationship between gut microbiome and CAR T-cell therapy response

Neural-network-based image recognition models for examining SCC defects

Innovative method to quickly identify bacteria in fluids

Lieber Institute awarded $1 million grant to foster racial diversity across neuroscience

Insilico Medicine: IND application for first generative AI-designed drug for COVID-19 approved

Artificial intelligence creates proteins to hasten chemical reactions

Improved efficacy of advanced genome editing with machine learning

Pungent ginger constituent puts white blood cells on heightened alert

MD Anderson and Replay launch new company pioneering T cell receptor NK cell therapies

New platform to study the feeding behavior of mosquitoes

Newly discovered gene signature accurately predicts the functioning of P53 variants

Deep learning model can accurately predict the growth of deadly brain tumors

Using data-driven computer models to predict light emission properties of iridium-centered chemicals

AI-based strategy helps discover high-affinity antibody drugs

The Journal, Artificial Intelligence in the Life Sciences, Highlights the Contributions of Women in Artificial Intelligence in the Life Sciences

AI develops first-ever functional artificial protein

Researchers use supercomputer to unveil new methods for DNA mosaic recognition

Study helps to understand the molecular mechanisms underlying complex taste sensations

Driving Support for Pharmaceutical Testing Through Continuous Innovation

From Memory to Metaplasticity: Unraveling the Brain's Secrets

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

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