Neurology News and Research

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New research helps illuminate a surprising mind-body connection

New research at Washington University School of Medicine in St. Louis helps illuminate a surprising mind-body connection.

15 Sep 2020

Researchers perform massive and detailed cellular energy audit

TK Adenosine triphosphate, or ATP, is the cellular energy currency that is as valuable to the human body as the dollar is to the US economy. Too high or too low levels of ATP in some cell types have been linked to a variety of diseases.

31 Aug 2020

Study looks into safety and early outcomes of gene therapy for spinal muscular atrophy

In May 2019, the U.S. Food and Drug Administration (FDA) approved a gene replacement therapy for the inherited, progressive neuromuscular disease 5q-linked spinal muscular atrophy (SMA).

26 Aug 2020

New bioluminescent reporter tracks DNA double stranded break repair in cells

A new bioluminescent reporter that tracks DNA double stranded break (DSB) repair in cells has been developed by researchers from Massachusetts General Hospital (MGH) and the Academia Sinica in Taiwan.

24 Aug 2020

Cashew shell compound shows therapeutic potential for demyelinating diseases

In laboratory experiments, a chemical compound found in the shell of the cashew nut promotes the repair of myelin, a team from Vanderbilt University Medical Center reports today in the Proceedings of the National Academy of Sciences.

From Vanderbilt University 19 Aug 2020

Single-cell analysis uncovers new details concerning mitochondrial diseases

Investigators led by a team at Massachusetts General Hospital (MGH) have made discoveries at the single cell level to uncover new details concerning mitochondrial diseases-- inherited disorders that interfere with energy production in the body and currently have no cure.

14 Aug 2020

Researchers develop new method to diagnose brain tumor without incisions

Brain tumors are typically diagnosed using MRI imaging, as taking a sample for a tissue biopsy is risky and may not be possible due to tumor location or a patient's poor health conditions.

10 Aug 2020

Study shows how neurons communicate when confronted with stroke

Research led by Nicolas Bazan, MD, PhD, Boyd Professor and Director of the Neuroscience Center of Excellence at LSU Health New Orleans School of Medicine, and Ludmila Belayev, MD, LSU Health New Orleans Professor of Neuroscience, Neurology and Neurosurgery, has unlocked a key fundamental mechanism in the communication between brain cells when confronted with stroke.

7 Aug 2020

Rutgers expert highlights the effects of climate change on allergies, autoimmunity and the microbiome

Climate change and disruption of the ecosystem have the potential to profoundly impact the human body. Xue Ming, professor of neurology at Rutgers New Jersey Medical School, who recently published a paper in the International Journal of Environmental Research and Public Health on the effects of climate change on allergies, autoimmunity and the microbiome -- the beneficial microorganisms that live on and inside the human body -- discusses how the delicate balance of the environment affects conditions such as allergies, autism and immune disorders.

6 Aug 2020

Identifying a new genetic cause of inherited neuropathy

Inherited mutations in a gene that keeps nerve cells intact were shown, for the first time, to be a driver of neuropathy known as Charcot-Marie-Tooth disease.

4 Aug 2020

Grotesque side effects from unproven stem cell therapies more common than thought

Grotesque side effects from unproven 'stem cell' therapies are more common than we realized, reports a team of researchers led by UConn Health in Annals of Neurology on July 29.

30 Jul 2020

Specific protein found at high levels in the blood of people with early signs of Alzheimer's

Two decades or more before symptoms arise, plaques of a sticky protein called amyloid begin forming in the brains of people later diagnosed with Alzheimer's disease.

29 Jul 2020

Virginia Tech scientists reveal molecular cause underlying rare genetic disorder

Virginia Tech scientists have revealed how a nonfunctioning version of an ordinary gene impairs brain structure and function. The findings help explain a genetic form of microcephaly -- a condition where babies' heads are small and grow more slowly than their peers.

28 Jul 2020

Computational tool can help study APA mechanism that regulates gene expression

Scientists keen on solving the regulation of genes implicated in human health and disease are widening their horizons by closely APA.

27 Jul 2020

Genes and cardiovascular health contribute to a person's dementia risk

Genes and cardiovascular health each contribute in an additive way to a person's risk of dementia, U.S. researchers including Sudha Seshadri, MD, and Claudia Satizabal, PhD, of The University of Texas Health Science Center at San Antonio (UT Health San Antonio) reported July 20 in the journal Neurology.

21 Jul 2020

High concentrations of blood sodium can influence the biological clock of mice

A new study from McGill University shows that increases in the concentrations of blood sodium can have an influence on the biological clock of mice, opening new research avenues for potentially treating the negative effects associated with long-distance travel or shift work.

10 Jul 2020

How upregulation of a single gene by SARs-CoV-2 can trigger cytokine storm

The SARS-CoV-19 virus initially has a limited capability to invade, attacking only one intracellular genetic target, the aryl hydrocarbon receptors (AhRs).

29 Jun 2020

Alzheimer's: New Gene May Drive Earliest Brain Changes

A newly discovered Alzheimer's gene may drive the first appearance of amyloid plaques in the brain, according to a study led by researchers.

23 Jun 2020

Disrupted circadian rhythms in older adults linked to increased risk of Parkinson's disease

Older men who have a weak or irregular circadian rhythm guiding their daily cycles of rest and activity are more likely to later develop Parkinson's disease, according to a new study by scientists at the UC San Francisco Weill Institute for Neurosciences who analyzed 11 years of data for nearly 3,000 independently living older men.

16 Jun 2020

Toxic tau may spread in the brain via connected neurons

Toxic versions of the protein tau are believed to cause the death of neurons of the brain in Alzheimer's disease.

1 Jun 2020