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New stem cell therapy shows promise to help patients with non-healing diabetic foot ulcers

According to the results of a phase 1 clinical trial just published in STEM CELLS Translational Medicine, a new stem cell therapy shows promise of making diabetes-related amputations a thing of the past.

8 Apr 2021

Novel, non-invasive biomarker test could help measure, track performance of senolytics

Scientists from Buck Institute have identified and are now developing an innovative, non-invasive biomarker test that could help quantify and track the performance of senolytics—a class of drugs that selectively destroy senescent cells.

5 Apr 2021

New label-free immune profiling assay to assess rapidly changing host immune response

Researchers from Critical Analytics for Manufacturing Personalized-Medicine (CAMP), an Interdisciplinary Research Group (IRG) at the Singapore-MIT Alliance for Research and Technology (SMART), MIT's research enterprise in Singapore, have developed a new label-free immune profiling assay that profiles the rapidly changing host immune response in case of infection, in a departure from existing methods that focus on detecting the pathogens themselves, which can often be at low levels within a host.

26 Mar 2021

Study maps structure, mechanism of membrane enzyme that has a role in chronic inflammation, cancer

A majority of the drugs work through the membranes surrounding the cells of the body.

22 Mar 2021

Psychoactive component of marijuana stays in breast milk for up to six weeks, study finds

In a new study published in JAMA Pediatrics, researchers at Children's Hospital Colorado have found that tetrahydrocannabinol (THC), the psychoactive component of marijuana, stays in breast milk for up to six weeks, further supporting the recommendations of the American Academy of Pediatrics, the American College of Obstetricians and Gynecologists and the Academy of Breastfeeding Medicine to abstain from marijuana use during pregnancy and while a mother is breastfeeding.

9 Mar 2021

Study explores factors that influence the disparities in sickle cell disease

Even a single letter variation in a single gene, acquired from both parents, could mean a lifetime of pain and anemia for 20 million individuals across the world.

2 Mar 2021

Study may lead to alternative treatment for potentially addictive opioid pain killers

When two naturally occurring lipids are altered using a process called epoxidation, they are transformed into powerful agents that target numerous cannabinoid receptors in neurons, disrupting pathways that promote inflammation and pain.

11 Feb 2021

An outlook on latest trends in peptide drug discovery and development

Currently, there are more than 80 peptide drugs on the global market and about twice as many in clinical development. Due to their beneficial properties, these biomolecules play already an important role in the treatment of diseases such as diabetes, cancer, hormone disorders, HIV infection, and multiple sclerosis.

11 Feb 2021

Using insights from neuroscience to build modern robots

Today, neuroscience and robotics are developing hand in hand. Mikhail Lebedev, Academic Supervisor at HSE University's Centre for Bioelectric Interfaces, spoke about how studying the brain inspires the development of robots.

4 Feb 2021

Cancer survivors face barriers in maintaining a healthy diet

New research and analysis appearing in the Journal of the Academy of Nutrition and Dietetics, published by Elsevier, highlights the barriers cancer survivors face in maintaining a healthy diet, as well as the role nutrition may play in cancer risk and treatment.

4 Feb 2021

Metabolites may be predictive indicators for recurrent major depressive disorder

Researchers at University of California San Diego School of Medicine, in collaboration with Dutch scientists, have found that certain metabolites -- small molecules produced by the process of metabolism -- may be predictive indicators for persons at risk for recurrent major depressive disorder.

13 Jan 2021

Gene expression database sheds light on pneumococcal infection

Researchers at the University of Maryland School of Medicine published one of the most comprehensive analyses of how genes get expressed during infection (known as a transcriptome).

16 Dec 2020

Specific cellular pathways in the fetal gut may reactivate Crohn’s Disease

Researchers have successfully monitored the initial stages of gut development in a human fetus, in explicit detail.

8 Dec 2020

Environmental and exogenous compounds can interact with therapeutic drugs, shows study

According to scientific estimations, humans are exposed to at least 10,000 to 100,000 environmental and exogenous compounds in an individual lifetime, which are mainly absorbed through our dietary.

3 Dec 2020

Study: Painkillers interfere with auxin flow essential for developmental processes in plants

For centuries humans were using willow barks to treat a headache or an inflamed tooth. Later, the active ingredient, the plant hormone salicylic acid, was used to develop painkillers like Aspirin.

2 Dec 2020

Ultra-processed foods increase risk of muscle pain

A research team from the Universitat Rovira i Virgili (Tarragona - Spain) has observed that following a diet rich in fats and sugars from ultra-processed foods (such as sweet rolls and pastries) for a six-week period increases the number of inflammatory molecules in the organism, which increases the excitability of the muscle nerves.

16 Nov 2020

Researchers identify potential genetic target for treating painful, invasive form of endometriosis

Michigan State University researchers have identified a potential genetic target for treating an especially painful and invasive form of endometriosis.

12 Nov 2020

Genetically edited form of herpes simplex virus outperforms key vaccine candidate

A genetically edited form of a herpes simplex virus -- rewired to keep it from taking refuge in the nervous system and eluding an immune response -- has outperformed a leading vaccine candidate in a new study from the University of Cincinnati, Northwestern University and the University of Nebraska-Lincoln.

9 Nov 2020

Study shows statins have different effects on different parts of the body

Contrary to expectation, treatment with statins has a different effect on blood cells than on muscle cells, a new study from the University of Copenhagen reveals.

2 Nov 2020

Severe ulcerative colitis linked to newly-discovered strain of oral bacteria

Severe ulcerative colitis - a form of inflammatory bowel disease (IBD) - has been linked to a newly-discovered strain of oral bacteria, a study led by UNSW Sydney has found.

From The University of New South Wales (UNSW) 30 Oct 2020