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Tiny Protein Interacts with Ion Channels to Make Our Eyes Sensitive to Dim Light

Using cryo-electron microscopy and mass spectrometry, researchers from PSI have deciphered the structure of an ion channel found in the eye while it interacts with the protein calmodulin – a structure that has eluded scientists for three decades.

4 Apr 2023

Potential Treatment Pathway for IBD Emerges from Microbe-Gut Signaling Study

Fresh insights into how our bodies interact with the microbes living in our guts suggest that a two-drug combination may offer a new way to treat inflammatory bowel diseases such as Crohn's disease and ulcerative colitis.

4 Apr 2023

Endothelial Deletion of Wt1 Gene During Coronary Vessel Formation Affects Embryonic Heart Development

How is the mammals' heart formed? What role do endothelial cells play? Do the same pathways and genes involved in the formation of the embryonic heart also play a role in repair processes?

4 Apr 2023

Researchers Explain How a Single Mutation Causes Ataxia

Worldwide, only a handful of patients are known to suffer from episodic ataxia type 6, a neurological disease that causes transient loss of muscle control.

4 Apr 2023

Triglyceride Cycling Process Modifies Stored Fatty Acids

Fat molecules serve as energy storage for fat cells. They consist of three fatty acids attached to a backbone of glycerol.

4 Apr 2023

SARS-CoV-2 Spike Protein Induces Memory Loss After COVID-19

Patients diagnosed with post-COVID-19 syndrome often experience cognitive and memory impairments.

4 Apr 2023

Jumping Genes in Various Cancers may be Used to Direct Novel Immunotherapies to Tumors

New research from Washington University School of Medicine in St. Louis suggests that transposable elements in various cancers potentially may be used to harness novel immunotherapies against tumors that don't typically respond to immune-based treatments. Shown is a 3D rendering of cancer cells.

4 Apr 2023

Designing a Lipid Nanoparticle to Safely Deliver mRNA to the Pancreas

Therapeutics that use mRNA-;like some of the COVID-19 vaccines-;have enormous potential for the prevention and treatment of many diseases.

4 Apr 2023

New Resource Provides a Better Annotation of the Genome and Understanding of Variant Impact

Each person has about 4 million sequence differences in their genome relative to the reference human genome.

4 Apr 2023

MET+LEU Cocktail Prevents Cellular Senescence and Disrupted Proteostasis Induced by Myotube Atrophy

A new research paper was published on the cover of Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 6, entitled, "Cellular senescence and disrupted proteostasis induced by myotube atrophy are prevented with low-dose metformin and leucine cocktail."

3 Apr 2023

Newly Identified Rare Genetic Variants Could Point to One of the General Mechanisms Driving AMD

A study from the National Eye Institute (NEI) identified rare genetic variants that could point to one of the general mechanisms driving age-related macular degeneration (AMD), a common cause of vision loss in older adults.

3 Apr 2023

Astrocytes in the Brain may Play a Key Role in Regulating Information

Long thought of as "brain glue," the star-shaped cells called astrocytes-;members of a family of cells found in the central nervous system called glial that help regulate blood flow, synaptic activity, keep neurons healthy, and play an important role in breathing.

3 Apr 2023

First Steps Driving Antibiotic Resistance Discovered

Antibiotic resistance is a global health threat. In 2019 alone, an estimated 1.3 million deaths were attributed to antibiotic resistant bacterial infections worldwide.

3 Apr 2023

New, Effective Method can Make Rare Cell Types and Disease Patterns Visible in Tissue

The human body contains more than 30 trillion cells. Until recently, the sheer number of cells in the organism meant that approaches to understanding human diseases and developmental processes based on the analysis of single cells were a futuristic vision.

3 Apr 2023

Cell News and Research

Tiny Protein Interacts with Ion Channels to Make Our Eyes Sensitive to Dim Light

Potential Treatment Pathway for IBD Emerges from Microbe-Gut Signaling Study

Endothelial Deletion of Wt1 Gene During Coronary Vessel Formation Affects Embryonic Heart Development

Researchers Explain How a Single Mutation Causes Ataxia

Triglyceride Cycling Process Modifies Stored Fatty Acids

SARS-CoV-2 Spike Protein Induces Memory Loss After COVID-19

Jumping Genes in Various Cancers may be Used to Direct Novel Immunotherapies to Tumors

Designing a Lipid Nanoparticle to Safely Deliver mRNA to the Pancreas

New Resource Provides a Better Annotation of the Genome and Understanding of Variant Impact

MET+LEU Cocktail Prevents Cellular Senescence and Disrupted Proteostasis Induced by Myotube Atrophy

Newly Identified Rare Genetic Variants Could Point to One of the General Mechanisms Driving AMD

Astrocytes in the Brain may Play a Key Role in Regulating Information

First Steps Driving Antibiotic Resistance Discovered

New, Effective Method can Make Rare Cell Types and Disease Patterns Visible in Tissue

CrestOptics Launches CICERO System to Provide All-in-One Solution for Widefield and Spinning Disk Confocal Microscopy

Two types of immune cells interact to give natural protection from tuberculosis

Study brings into sharper focus the structural details of SARS-COV-2 virus

UConn Health scientists explain why Shigella bacteria can infect humans but not mice

Newly developed toolkit uses small molecules to control the activity of synthetic RNA

New cold "coping" mechanism of plants could offer solutions to breeding more climate resilient crops

Driving Support for Pharmaceutical Testing Through Continuous Innovation

From Memory to Metaplasticity: Unraveling the Brain's Secrets

Revolutionizing Mass Spectrometry: A Deep Dive into Plasmion’s SICRIT® Technology

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