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Study Unveils Key Genetic Mechanism Behind Antibiotic Resistance in Bacteria

An international collaboration has achieved an important breakthrough in understanding the genetic mechanisms that allow bacteria to build resistance to drugs.

24 Jan 2025

New Insights into the Biological Basis of Bipolar Disorder

According to research published in Nature on January 22nd, 2025, an international team of psychiatric genetics researchers has discovered 298 regions of the genome with DNA variations that increase the risk for bipolar disorder, more than four times the number previously found.

24 Jan 2025

AI-designed proteins revolutionize snakebite treatment

Research highlights the potential of deep learning in creating proteins that neutralize snake venom, offering new solutions for neglected tropical diseases.

24 Jan 2025

Study Reveals How Immune Cells Adapt to Defend the Gut

Your gut is a battleground. The cells that line your small intestine have to balance two seemingly contradictory jobs: absorbing nutrients from food, while keeping a wary eye out for pathogens trying to invade your body.

23 Jan 2025

Breakthrough Achieved in Completing the Creation of First Synthetic Yeast Genome

Macquarie University researchers have worked with an international team of scientists to achieve a major milestone in synthetic biology by completing the creation of the final chromosome in the world's first synthetic yeast genome.

23 Jan 2025

OGT Delivers Superior MRD Detection Capabilities with New SureSeq Myeloid MRD Panel

Today, OGT announces the North American launch of its new next-generation sequencing (NGS) SureSeq™ Myeloid MRD Panel, which provides a flexible NGS workflow for the detection of ultra-low frequency measurable residual disease (MRD)-associated biomarkers in acute myeloid leukemia (AML).

23 Jan 2025

Genetic Mutations May Be Behind Epigenetic Clock of Aging

Researchers at University of California San Diego School of Medicine have published results that shed new light on an old question: what causes aging at the molecular level? Their findings, published in Nature Aging, describe a never-before-seen link between the two most accepted explanations: random genetic mutations and predictable epigenetic modifications.

22 Jan 2025

Ancient Viral DNA Plays a Key Role in Embryonic Development

More than half of the human genome is made up of thousands of remnants of ancient viral DNA, known as transposable elements, which are pervasive across the tree of life.

21 Jan 2025

Immune System Insights Could Lead to Tailored Treatments for Childhood Cancer

Researchers at Karolinska Institutet and the Astrid Lindgren Children's Hospital in Sweden have determined how children's immune systems react to different kinds of cancer depending on their age.

21 Jan 2025

Mapping Global Microbial Diversity Using Genomic Sequencing Data

Metagenomic datasets could help map out microbial diversity hotspots. Published January 17, 2025 in Science Advances, researchers at the U.S. Department of Energy (DOE) Joint Genome Institute (JGI), a DOE Office of Science User Facility located at Berkeley Laboratory, have taken stock of the current state of microbial genomic biodiversity.

20 Jan 2025

Unveiling the Interplay of DNA and RNA Epigenetics

The genes contain all the instructions the human body needs to function, but their expression must be carefully regulated to guarantee that each cell performs its function as best it can.

20 Jan 2025

Understanding the Impact of Microbial Associations on Insect Evolution

The evolutionary success of leaf beetles, the most varied herbivores on Earth, was investigated by researchers from the Max Planck Institute for Chemical Ecology in Jena, Max Planck Institute of Biology in Tübingen, Germany, and a group of scientists from around the world.

20 Jan 2025

Researchers Develop Method to Produce Strigolactones Using Microbial Cell Factories

Sometimes just using a different tool makes the job a whole lot easier. A team of researchers co-led by the University of California San Diego has developed a method to produce a special class of plant hormones, known as strigolactones, at unprecedented levels using microbial cell factories.

17 Jan 2025

Scientists Discover Surprising Directional Flexibility in DNA-Shaping Motors

Scientists from Delft, Vienna, and Lausanne discovered that the protein machines that shape our DNA can switch direction.

17 Jan 2025

Study Unveils Surprising Cause of Brain Cell Death in Huntington's Disease

Scientists at the Broad Institute of MIT and Harvard, Harvard Medical School, and McLean Hospital have discovered a surprising mechanism by which the inherited genetic mutation known to cause Huntington's disease leads to the death of brain cells.

17 Jan 2025

New study reveals how genes switch on and off in human cells

An international group of scientists has made a significant advancement in their understanding of the regulation of gene expression throughout the human genome.

17 Jan 2025

New Approach Aims to Make CRISPR Therapy Safer and More Effective

CRISPR is a powerful gene-editing tool that holds enormous potential for treating genetic diseases by allowing scientists to cut, replace, or delete mutations in DNA.

16 Jan 2025

Researchers Develop Strategy to Boost Pharmaceutical Production in CHO Cells

An international team of researchers led by the University of California San Diego has developed a new strategy to enhance pharmaceutical production in Chinese hamster ovary (CHO) cells, which are commonly used to manufacture protein-based drugs for treating cancer, autoimmune diseases and much more.

16 Jan 2025

Researchers Develop Method to Visualize Nanocarriers at Single-Cell Level

How can we ensure that life-saving drugs or genetic therapies reach their intended target cells without causing harmful side effects? Researchers at Helmholtz Munich, Ludwig-Maximilians-Universität (LMU) and Technical University Munich (TUM) have taken an important step to answer this question.

16 Jan 2025

Epigenetic Mechanism Controls Placental Blood Vessel Formation

If the development of blood vessels in the placenta is impaired, fetal growth retardation may result. Scientists from the German Cancer Research Center (DKFZ) and the Mannheim Medical Faculty of Heidelberg University discovered that the correct development of functioning blood vessels in the mouse placenta is controlled epigenetically: One of the enzymes that modify gene activity using methyl groups is responsible.

16 Jan 2025