Pathology News and Research

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Pathology is the study and diagnosis of disease through examination of organs, tissues, bodily fluids, and whole bodies (autopsies). The term also encompasses the related scientific study of disease processes, called General pathology. Medical pathology is divided in two main branches, Anatomical pathology and Clinical pathology. Veterinary pathology is concerned with animal disease whereas Phytopathology is the study of plant diseases.

Blending multiple maps uncover new genetic causes of blindness

In a new study, Ran Elkon and Ruth Ashery-Padan of Tel Aviv University, Israel, and colleagues discovered a new genetic risk factor for adult-onset macular degeneration (AMD) by combining a map of gene regulatory sites with disease-associated loci.

18 Jan 2023

Plankton could hold key for understanding link between ocean pollution and human health

Plankton may offer a way to monitor historical marine pollution trends, and could be used to predict trends in human health, according to new research.

10 Jan 2023

Marine plankton samples can help understand the link between ocean pollution and chronic illnesses

Using samples from an almost century-old, ongoing survey of marine plankton, researchers at University of California San Diego School of Medicine suggest that rising levels of manmade chemicals found in parts of the world's oceans might be used to monitor the impact of human activity on ecosystem health, and may one day be used to study the connections between ocean pollution and land-based rates of childhood and adult chronic illnesses.

9 Jan 2023

New technologies reveal cross-cutting breakdowns in Alzheimer’s disease

A figure from the paper depicts pathways perturbed in Alzheimer's disease. Below examples are listed for each pathway by major brain cell type. Image Credit: The Picower Institute.

4 Jan 2023

Common food dye can be a potential dietary trigger for IBDs, study shows

Long-term consumption of Allura Red food dye can be a potential trigger of inflammatory bowel diseases (IBDs), Crohn's disease and ulcerative colitis, says McMaster University's Waliul Khan.

21 Dec 2022

Major development in re-treatment with CAR T therapy

At the American Society of Hematology (ASH) Annual Meeting in 2022 (Abstract 2016), researchers from the Abramson Cancer Center at the University of Pennsylvania presented preliminary findings from an ongoing Phase I clinical trial demonstrating effective re-treatment with CAR T cell therapy for patients whose cancers relapsed after prior CAR T therapy.

12 Dec 2022

New 3D organoid model reveals a possible biological target for treating GEJ cancers

Researchers at Johns Hopkins Medicine say they have created a laboratory-grown three-dimensional "organoid" model that is derived from human tissue and designed to advance understanding about how early stages of cancer develop at the gastroesophageal junction (GEJ) — the point where the digestive system's food tube meets the stomach.

2 Dec 2022

Acute infection disrupts the healthy balance between the good and bad gut microbes

Rutgers researchers examined the impact of COVID-19 on patients’ microbiomes, the group of microbes that live in and on the human body.

From Rutgers University 30 Nov 2022

Tackling epilepsy with a potential new drug

One of the epilepsy types that are most prevalent worldwide is temporal lobe epilepsy (TLE). Although there are symptomatic medications available, one-third of TLE patients are still not responding to the current course of treatment, necessitating the urgent need for new drug targets.

25 Nov 2022

Improving potential of cellular therapies with CAR T therapy

CAR T cells, or engineered immune cells, have demonstrated to the world the potential of customized immunotherapies to treat blood cancers. Researchers have just released highly encouraging preliminary data for CAR T therapy in a small group of lupus patients.

25 Nov 2022

Revitalized immune cells improve waste removal from the brain

Damaged protein clusters in the brain are a hallmark of many neurodegenerative diseases, including Parkinson’s, Alzheimer’s, and others. Although they have made significant efforts, scientists have only partially succeeded in finding treatments for these conditions by removing these toxic clusters.

11 Nov 2022

RNA-edited regions in brain shed light on neurodevelopment and disease

Numerous sites in the brain where RNA is altered over the course of a person’s lifespan through a process known as adenosine-to-inosine (A-to-I) editing have been identified by Mount Sinai researchers.

3 Nov 2022

New tool advances potential means to deliver gene therapy

Researchers from Johns Hopkins Medicine claim to have successfully “slid” genetic instructions into a cell and produced essential proteins that were lacking from those cells using a cell’s normal process for creating proteins.

1 Nov 2022

Gene governing cell division could shield against Alzheimer’s

According to a recent study by researchers at the University of Colorado Anschutz Medical Campus, the overexpression of a gene linked to cell division and the structure and function of neurons could prevent and protect against cognitive deterioration in both mice and people with Alzheimer’s disease (AD).

28 Oct 2022

NATA accreditation for BGI Australia to perform whole exome sequencing

The National Association of Testing Authorities (NATA) has accredited BGI Australia’s lab to conduct clinical Whole Exome Sequencing in Australia, opening the door for the multinational life sciences company to offer clinical sequencing services for locating potential disease-causing genetic changes.

25 Oct 2022

The influence of fatty acid metabolism on plant immunity

Most people do not realize that fatty acids can be found in a nutritious salad. Although fatty acids, lipids, and fats may seem unappealing, they are essential to human life and to the plants that are consumed.

17 Oct 2022

Fungus can be used for biological control of banana borers and Fusarium wilt

The banana borer Cosmopolites sordidus and the disease Fusarium wilt, caused by the soil-borne fungus Fusarium oxysporum, are among the most harmful pests that threaten the livelihoods of banana growers, who face major challenges in attempting to control them.

29 Sep 2022

The exchange of nutrients between the mother and fetus mirrored by ‘placenta-on-a-chip’

Plasmodium falciparum infections can result in placental malaria, which can have serious consequences for both mother and child. Nearly 200,000 newborn fatalities annually from placental malaria, primarily as a result of low birth weight, as well as 10,000 maternal deaths.

27 Sep 2022

The master regulator behind the fungal infection of wheat identified

The most damaging fungal disease of wheat farmed in temperate regions worldwide, Septoria tritici blotch, is brought on by the fungus Zymoseptoria tritici.

From University of Exeter 27 Sep 2022

WEHI receives $2.5 million fund to develop personalized cancer treatments

With a $2.5 million fund received from the Medical Research Future Fund (MRFF), a new genomics project led by WEHI will develop precision medicine and customized cancer therapy for Australians.

From Walter and Eliza Hall Institute of Medical Research (WEHI) 27 Sep 2022