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Molecular dynamic simulations may contribute to structure-based drug design

Uppsala University scientists have reported that they have developed a new way to predict how unique molecules that can be employed in novel immunotherapy.

26 Jun 2020

Scientists pinpoint mutations that makes bacteria deadlier

As far as humans are concerned, bacteria can be classified as either harmful, pathogenic bacteria and harmless or beneficial non-pathogenic bacteria.

26 Jun 2020

Lesion segregation can drive complex patterns of mutations in tumor genomes

Researchers from the German Cancer Research Center, Cambridge, and Edinburgh have been analyzing the evolution of tumors after chemical damage.

26 Jun 2020

Researchers discover new druggable pathway linked with tuberous sclerosis

Tuberous sclerosis complex (TSC) is a neurological disorder causing non-cancerous tumors, called cortical tubers, to grow throughout the brain and body, as well as other conditions like epilepsy and autism.

25 Jun 2020

Turning biomass DNA into degradable materials

DNA has a lot of handy uses. It stores the blueprint of genetic code. It helps usher along the evolution of species.

25 Jun 2020

Study shows how chemicals cause complex cell mutations

Fresh insights into why some harmful substances are so efficient at causing cancer could aid the quest for better treatments.

25 Jun 2020

Newly designed vesicles can help deliver drugs

Researchers have produced spherical and hollow sacks called vesicles using RNA and protein.

24 Jun 2020

Researchers discover unknown enzyme activity towards human endogenous substrates

Scientists have identified an enzymatic activity towards common drugs as well as significant human endogenous substrates, that was previously not known.

24 Jun 2020

Chemist Develops Potential Drug To Treat Type 2 Diabetes Without Harsh Side Effects

Professor Dr. Robert P. Doyle has developed a new drug to treat type 2 diabetes in millions of patients who are seeking to better control their blood sugar.

24 Jun 2020

University of Kentucky collaborates with Atomwise to explore potential COVID-19 therapies

The University of Kentucky announced a research collaboration with Atomwise, an industry leader in using artificial intelligence (AI) for small molecule discovery, to explore potential COVID-19 therapies.

24 Jun 2020

Research unravels molecular circuitry that controls cancer growth and spread

Research led by Queen Mary University of London has revealed novel insights into the molecular circuitry controlling cancer cell growth and spread. The findings highlight new pathways involved in these key processes of cancer progression that may represent targets for therapies.

24 Jun 2020

Preventing sugar uptake increases cancer cells' sensitivity to chemotherapy

By preventing sugar uptake, researchers succeeded in increasing the cancer cells' sensitivity to chemotherapeutic treatment.

24 Jun 2020

Novel precision medicine targets cancer's DNA defenses

A new precision medicine targeting cancer's ability to repair its DNA has shown promising results in the first clinical trial of the drug class.

23 Jun 2020

New LI383 molecule can help treat opioid-related disorders

A novel molecule LIH383 developed by scientists at the Luxembourg Institute of Health binds to and inhibits a formerly unknown opioid receptor in the brain.

22 Jun 2020

Researchers unlock a weakness in common type of cancer cells

Like any cells in the body, cancer cells need sugar - namely glucose - to fuel cell proliferation and growth. Cancer cells in particular metabolize glucose at a much higher rate than normal cells.

19 Jun 2020

Discovery could lead to a new toolset for cancer drug development

In the watery inside of a cell, complex processes take place in tiny functional compartments called organelles. Energy-producing mitochondria are organelles, as is the frilly golgi apparatus, which helps to transport cellular materials. Both of these compartments are bound by thin membranes.

19 Jun 2020