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Discovery of Novel Adrenal Cell Type Linked to Monogamy in Oldfield Mice

What makes the oldfield mouse steadfastly monogamous throughout its life while its closest rodent relatives are promiscuous? The answer may be a previously unknown hormone-generating cell, according to a new study published online today in Nature from scientists at Columbia's Zuckerman Institute.

16 May 2024

The Adrenaline Puzzle Solved: Scientists Untangle Key Cell Receptor's Inner Workings

Through an international collaboration, scientists at St. Jude Children's Research Hospital leveraged data science, pharmacology and structural information to conduct an atomic-level investigation into how each amino acid in the receptor that binds adrenaline contributes to receptor activity in the presence of this natural ligand.

26 Dec 2023

Scientists Unlock the Structure of Vesicular Monoamine Transporter 2

Neurons talk to each other using chemical signals called neurotransmitters. Scientists at St. Jude Children's Research Hospital have drawn on structural biology expertise to determine structures of vesicular monoamine transporter 2 (VMAT2), a key component of neuronal communication.

2 Nov 2023

Astrocytes Pull the Handbrake to Drive the Brain to a More Relaxed State

A brimming inbox on Monday morning sets your head spinning. You take a moment to breathe and your mind clears enough to survey the emails one by one.

5 Apr 2023

Flavanols enhance browning of adipose tissue by activating the sympathetic nervous system

In cold conditions, brown adipose tissue (BAT) or brown fat generates heat to keep the body warm. Compared with white adipose tissue, BAT has more mitochondria-;subcellular organelles associated with energy production-;which allows it to burn calories and produce heat by activating the mitochondrial uncoupling protein 1 (Ucp-1).

3 Feb 2022

Study suggests dietary intake of flavan-3-ols could help prevent obesity

14 Dec 2021

Molecular dynamic simulations may contribute to structure-based drug design

Uppsala University scientists have reported that they have developed a new way to predict how unique molecules that can be employed in novel immunotherapy.

26 Jun 2020