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Advanced Sequencing Uncovers Cause of Rare Mitochondrial Encephalopathy

Mitochondrial diseases are among the most prevalent hereditary metabolic disorders, known to occur in one out every 5000 births.

19 Nov 2024

Study Links Archaic Gene Variant to Health Risks in First Nations Oceanians

An ancient gene mutation among First Nations inhabitants of Oceania may make them more susceptible to infectious diseases like influenza, according to a new study by scientists at the University of Colorado Anschutz Medical Campus.

30 Oct 2024

New Approach for Targeted Genome Editing in Wild Populations

Researchers from Macquarie University and the California Institute of Technology have discovered a novel method that, when published in Nature Communications on August 13th, 2024, might make it easier and more controllable for scientists to modify the genetic composition of wild populations than when using gene drives.

14 Aug 2024

Genetic Analysis of Potato and Phytophthora infestans During and After the Irish Potato Famine

In an examination of the genetic material found in historic potato leaves, North Carolina State University researchers reveal more about the tit-for-tat evolutionary changes occurring in both potato plants and the pathogen that caused the 1840s Irish potato famine.

6 Aug 2024

New RNA Sequencing Dataset Reveals Genetic Diversity Across Global Populations

An open-access dataset of RNA sequences from lymphoblastoid cell lines of 731 individuals spanning 26 populations and five continental groups.

24 Jul 2024

Study Offers Insights Genetic Variants Influencing Pubertal Timing

Genes can indirectly influence the age at which girls have their first period by accelerating weight gain in childhood, a known risk factor for early puberty, a Cambridge-led study has found.

2 Jul 2024

GSE3 Gene Editing Paves the Way for Mechanized Hybrid Rice Breeding

In a study published in Nature Plants, Prof. LI Yunhai from the Institute of Genetics and Developmental Biology (IGDB) of the Chinese Academy of Sciences and Profs. ZHU Xudong and WANG Yuexing from the China National Rice Research Institute have identified an ideal small grain size gene, GSE3.

5 Jun 2024

Study Reveals Allele-Specific DNA Methylation in Hybrid Poplar Regeneration

Understanding plant regeneration at the molecular level is pivotal for advancements in genetic transformation and genome editing.

27 May 2024

Glycosylation and its Role in Human Health and Disease

The current understanding of glycosylation genetics in mammals and the consequences of mutations that impact glycosylation.

16 May 2024

Researchers Identify RNA-Regulator Brat as Key Player in Restraining Tissue Regeneration

Some animals possess the remarkable ability to regenerate lost structures, exemplified by a lizard regrowing its tail.

20 Mar 2024

Paleogenomics Unveils the Evolutionary Journey of Modern Humans

Writing a commentary in the 50th anniversary issue of Cell, FU Qiaomei and E. Andrew Bennett, both of the Institute of Vertebrate Paleontology and Paleoanthropology (IVPP) of the Chinese Academy of Sciences, explored the contribution of paleogenomics to our understanding of the evolution of modern humans.

1 Mar 2024

Study Identifies Risk Genes and Regulatory Variants for Colorectal Cancer by Integrating Multi-Omics Data

This study was led by Prof. Xiao-Ping Miao' team from the School of Public Health, Wuhan University, in collaboration with Prof. Shaokai Zhang from the Henan Cancer Hospital.

2 Nov 2023

The Recognition of Polymorphic Csd Proteins Defines Sex in Honeybees

Until now, it has been unknown how a bee’s sex is decided. A team of biologists and chemists from Heinrich Heine University Düsseldorf (HHU) has found a critical gene and the chemical process that goes with it. They describe how this process is analogous to a dice game in the current edition of the scholarly journal Science Advances.

5 Oct 2023

New Halophyte Genome Sequence Sheds Light on Salt Tolerance Mechanisms

A Recent study conducted by Professor Qin Yuan's team from the Center for Genomics at the Haixia Institute of Science and Technology (Future Technology College) at Fujian Agriculture and Forestry University has been published in the prestigious journal Horticulture Research, which is a leading publication in the field of horticultural science.

25 Sep 2023

Linking Alzheimer's Genetic Marker and Higher Female Fertility

The Apolipoprotein-ε4 (APOE-ε4) allele has been linked to an increased risk for several types of diseases in aging populations, particularly Alzheimer’s and cardiovascular disease.

10 Aug 2023

Study Identifies a Gene That Largely Controls Weeping Growth in Apple

Plant geneticists have identified a mutation in a gene that causes the "weeping" architecture – branches growing downwards – in apple trees, a finding that could improve orchard fruit production.

21 Jul 2023

New Method can Help Identify Genome Differences Responsible for Variation in Plant Traits

Plants show enormous variety in traits relevant to breeding, such as plant height, yield and resistance to pests.

23 May 2023

A High-Throughput Assay for Identifying and Validating ECHS1 Enzyme Genetic Variants

The enzyme variations of mitochondrial enoyl-CoA hydratase short-chain 1 (ECHS1) are dysfunctional. In Japan, they are mostly responsible for mitochondrial disease.

19 May 2023

Genetic Study Sheds New Light on the Into- and Out-of-Taiwan Dispersals

The Austronesian language family is one of the largest in the world, comprising over 1,200 languages spoken from Madagascar to Hawaii. Dang Liu, Albert Min-Shan Ko and Mark Stoneking collected genome-wide data from 55 individuals from seven Taiwanese Austronesian groups and two Han-Taiwanese groups to study the genetic structure of Taiwan, the point of origin for all Austronesian-speaking peoples.

17 May 2023

Breakthrough "Gene Silencing" Technology Could Revolutionize the Development of DNAzymes

Researchers from the University of California, Irvine have developed a DNA enzyme – or DNAzyme – that can distinguish between two RNA strands inside a cell and cut the disease-associated strand while leaving the healthy strand intact.

9 May 2023