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Japanese Researchers Develop New Assay to Detect Epigenetic Toxicity

Chemicals used as food preservatives, flavoring agents, dyes, pesticides, cosmetics, cleaners, and other industrial materials are being increasingly recognized as a health hazard.

11 Apr 2025

Flies Get Drunk on Purpose—But Not for the Reasons You Think

Drosophila flies show a strong attraction to ethanol and methanol, driven by evolutionary benefits in mating success rather than psychological responses.

11 Apr 2025

IBL International Collaborates with Grifols on Advanced Biomarker Panels

IBL International GmbH, a Tecan company, which develops, manufactures and offers specialty diagnostics, today announced a strategic partnership with Grifols, a global healthcare company and leading producer of plasma-derived medicines and innovative diagnostic solutions, to transform the specialty diagnostics market.

9 Apr 2025

Researchers Identify Promising Drug Candidates for Previously “undruggable” Cancer Target

For the first time scientists have identified promising drug candidates that bind irreversibly with a notoriously “undruggable” cancer protein target, permanently blocking it.

21 Mar 2025

Structural Insights into uMtCK Offer New Pathways for Targeting Cancer Energy Mechanisms

Cancer cells have an insatiable appetite for energy as they multiply more rapidly than normal cells. Greedy cancer cells hijack various cellular functions to find and exploit energy and other resources, including a group of enzymes that help normal cells maintain a balance of energy.

8 Mar 2025

New ctDNA Model Enhances Metastatic Cancer Surveillance

In metastatic cancer surveillance, monitoring the actual concentrations of circulating tumor DNA (ctDNA) may be critical. Researchers showed that absolute ctDNA concentration thresholds can be defined to rule out or predict impending cancer progression.

25 Feb 2025

Mismatch Repair Genes Found to be Key Drivers of Huntington's Disease

A new UCLA Health study has discovered in mouse models that genes associated with repairing mismatched DNA are critical in eliciting damages to neurons that are most vulnerable in Huntington's disease and triggering downstream pathologies and motor impairment, shedding light on disease mechanisms and potential new ways to develop therapies.

12 Feb 2025

CN Bio Introduces PhysioMimix DILI Assay Kit to Enhance Drug Safety Testing

CN Bio, a leading provider of Organ-on-a-chip (OOC) Systems and solutions that accelerate drug discovery and development workflows, today announced the launch of its PhysioMimix® DILI assay kit: Human 24.

10 Feb 2025

The Cost of Being King: Alpha Baboons Trade Power for Survival

Research on male baboons reveals that alpha males face higher energetic costs and chronic stress, challenging assumptions about dominance and well-being.

3 Feb 2025

GET Model Unveils Gene Regulation with Unmatched Accuracy Across Cell Types

GET, a novel computational model, accurately predicts gene activity by analyzing chromatin accessibility and DNA sequences across diverse human cell types.

20 Jan 2025

New study reveals how genes switch on and off in human cells

An international group of scientists has made a significant advancement in their understanding of the regulation of gene expression throughout the human genome.

17 Jan 2025

Researchers Uncover Genetic and Environmental Interplay in Bacterial Growth

Genetic and environmental factors influence cell growth. Although previous studies have evaluated the influence of these factors on growth, conducting studies that assess such factors in a cross-talk manner is necessary.

8 Jan 2025

PlantRNA-FM: Bridging the Gap Between RNA Structure and Function

With PlantRNA-FM, researchers can systematically analyze plant RNA, uncovering functional motifs that play key roles in gene expression and stress responses.

23 Dec 2024

ALS Stem Cell Model Reveals Increased Susceptibility to Cell Death

Amyotrophic lateral sclerosis (ALS) is a fast-progressing neurodegenerative disease with an average survival time of three years. In ALS, certain types of neurons called motor neurons that are required for muscle contractions die off, leading to progressive paralysis affecting most muscles of the body. The molecular causes of ALS are poorly understood, and effective treatments are missing.

20 Dec 2024

From Yeast to Humans: Decoding the Link Between Nucleolar Size and Aging

Research reveals that nucleolar enlargement in yeast disrupts genomic integrity, linking size to lifespan and offering insights into aging mechanisms.

5 Dec 2024

Reduced Protein Mobility Linked to Chronic Diseases and Their Complications

Chronic diseases like type 2 diabetes and inflammatory disorders have a huge impact on humanity. They are a leading cause of disease burden and deaths around the globe, are physically and economically taxing, and the number of people with such diseases is growing.

28 Nov 2024